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The map label for this gene is yfnA [H]

Identifier: 148358166

GI number: 148358166

Start: 31779

End: 33170

Strand: Direct

Name: yfnA [H]

Synonym: LPC_0027

Alternate gene names: 148358166

Gene position: 31779-33170 (Clockwise)

Preceding gene: 148358162

Following gene: 148358169

Centisome position: 0.89

GC content: 39.87

Gene sequence:

>1392_bases
ATGGACTTGTTTCGTAAAAAAGATATAAAAGGGTCGCTAGACAATGAATCACATTTAGCTAAATGCCTTAGTGTTTTTGA
CCTTACCTTTTTGGGAGTGGGCGCGATTATAGGTGCTGGTATTTTCGTTCTTACAGGAATAGTAGCTGCCACTATAAGCG
GACCAGCCGTGATATTCTCCTATGTTGTTGCCGGATTTGCCTGCGCTTTTGCTGCCTTATCCTATGCTGAGTTGGCTGCC
AGCATAGGAGGATGTGGCAGTGCTTATGGATATGCTTACGCAGGATTTGGTGAATTAATCGCGTGGATCGTCGGATGGGA
TTTGTTATTGGAATATTCTATTGCTGTATCGGCTGTTTCTATCGGCTGGAGTGGTTATGCCAATGATTTTTTAATGGCTC
TGAAAATATTTATTCCGGCTAATTTATTACATGGTCCTGCTGACGGTGGGGATCTCAATATTTTAGCCATTTTGATCATA
GCTGTTTTAACTACATTATTAATTGTTGGTGTGAAATCCAGTTCTCGATTTAATAATATCATGGTGCTTGTTAAGCTTTT
GGTTATTTTTATTTTCATAGCTGTCGCATTTGGTGAAGTGAAGGTTGAAAATTGGTCTTCTTTCATGCCCTATGGTTGGG
CTGGTGTTATGAAAGGTGCTTCAATCATCTTTTTTGCCTACGTGGGGTTTGATGCTGTTTCTACTGCTGCTGAAGAAGCA
ATTAATCCTCAACGGGATTTGCCCATAGGGATAATCGCTTCTCTGGCTATTTGTACAGTGATCTATATTCTGGTTTCAGG
TTTATTAACCGGGATTGCTCATTACACTACTCTTAACGTTTCATCACCAATCAGTCATGTCCTGCTTGTCTTGGGTTATA
AAACAGCAGCCGGACTGGTCGGTGTAGGCGCAATTGCTGGTTTAACCACGGTTATGTTGGTTCTGTTCTATGGATTAACC
AGAGTATTTTTAGCAATGTCAAGGGATGGCTTATTGCCAAGGTTCTTATCCAAAACGAACGAACACACTAAAACACCAAT
TCGAATTATATTGCTATGTGGCATATTAATGGCATCTCTCGCTTCAGTAACTCCAATTGGTACCTTGGCCGAGCTGGTTA
ATATTGGAACCTTGTTTGCCTTTATTGTTGTTTGTGGAGGTGTTTTATATTTAAGGCGAACTCATCCTGATATGGAAAGG
CCATTCAAAACACCTTTTATGCCTTATGTTCCTATATTAGGTATAATAAGCTGTTTTTATTTAATTTTGAATTTGCCATG
GGTAACGATATTGCGTTTTATAATTTGGATGCTAGTTGGTATAGCGGTCTATTTTGCATTTAGCAGGACAAATAGTGCCT
TAAGTGTTGAGGGAGATTGTGCTGCTGAGTGA

Upstream 100 bases:

>100_bases
TGTAAGGTTTTGTTAGATGGAAGATAACCGGAGTTTATGTTTATTGATAACTTAAATTTTGGAAATAAACAATAAAAAAT
AAACCTGAGAGCATACTATC

Downstream 100 bases:

>100_bases
CGCCATAATCTAGGCAGTTGGTGAGATGGTCATAATAGCGGCAGCAACTAATGCTGCTGCTGGAATGGTAAGCAACCAAG
AGTAGAATATCCTGCGTAAA

Product: amino acid transporter PotE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDLFRKKDIKGSLDNESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPANLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAVAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE

Sequences:

>Translated_463_residues
MDLFRKKDIKGSLDNESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPANLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAVAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
>Mature_463_residues
MDLFRKKDIKGSLDNESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFSYVVAGFACAFAALSYAELAA
SIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVSIGWSGYANDFLMALKIFIPANLLHGPADGGDLNILAILII
AVLTTLLIVGVKSSSRFNNIMVLVKLLVIFIFIAVAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLVGVGAIAGLTTVMLVLFYGLT
RVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASLASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMER
PFKTPFMPYVPILGIISCFYLILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=35.6979405034325, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=35.2245862884161, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI258614005, Length=423, Percent_Identity=35.6973995271868, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI258614003, Length=423, Percent_Identity=35.6973995271868, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI181337167, Length=386, Percent_Identity=38.0829015544041, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI114326544, Length=429, Percent_Identity=34.7319347319347, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI114326550, Length=429, Percent_Identity=34.7319347319347, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI110347453, Length=399, Percent_Identity=37.0927318295739, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI7657683, Length=416, Percent_Identity=27.4038461538462, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI115648063, Length=446, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI115648022, Length=446, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI186910308, Length=412, Percent_Identity=27.9126213592233, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI186910306, Length=412, Percent_Identity=27.9126213592233, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI186910304, Length=412, Percent_Identity=27.9126213592233, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI71979932, Length=439, Percent_Identity=27.1070615034169, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI33286428, Length=449, Percent_Identity=26.0579064587973, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI187423910, Length=474, Percent_Identity=25.5274261603376, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI7657591, Length=474, Percent_Identity=25.5274261603376, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI87081869, Length=462, Percent_Identity=25.3246753246753, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082023, Length=445, Percent_Identity=26.0674157303371, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI2367353, Length=407, Percent_Identity=25.0614250614251, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789017, Length=357, Percent_Identity=24.0896358543417, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081708, Length=451, Percent_Identity=19.7339246119734, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790653, Length=418, Percent_Identity=21.0526315789474, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786694, Length=382, Percent_Identity=22.2513089005236, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788480, Length=456, Percent_Identity=23.4649122807018, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786789, Length=419, Percent_Identity=21.4797136038186, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=403, Percent_Identity=36.9727047146402, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17531343, Length=401, Percent_Identity=36.6583541147132, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17533459, Length=405, Percent_Identity=35.0617283950617, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17540018, Length=454, Percent_Identity=27.7533039647577, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17568033, Length=478, Percent_Identity=27.6150627615063, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17537453, Length=416, Percent_Identity=22.3557692307692, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=25.4010695187166, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71993915, Length=392, Percent_Identity=25, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=37.2596153846154, Blast_Score=263, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=37.2596153846154, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24667468, Length=402, Percent_Identity=37.3134328358209, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24668806, Length=410, Percent_Identity=36.3414634146341, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356285, Length=410, Percent_Identity=36.3414634146341, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24668802, Length=410, Percent_Identity=36.3414634146341, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI161077963, Length=400, Percent_Identity=34.25, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI281366235, Length=411, Percent_Identity=32.1167883211679, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI116007820, Length=411, Percent_Identity=32.1167883211679, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=32.1167883211679, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=32.1167883211679, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI45550968, Length=466, Percent_Identity=27.0386266094421, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921172, Length=466, Percent_Identity=27.0386266094421, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357367, Length=437, Percent_Identity=25.858123569794, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221331183, Length=460, Percent_Identity=26.7391304347826, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17647653, Length=460, Percent_Identity=26.7391304347826, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24664379, Length=460, Percent_Identity=26.7391304347826, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24651635, Length=417, Percent_Identity=25.8992805755396, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651633, Length=417, Percent_Identity=25.8992805755396, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49366; Mature: 49366

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFRKKDIKGSLDNESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YVVAGFACAFAALSYAELAASIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWSGYANDFLMALKIFIPANLLHGPADGGDLNILAILIIAVLTTLLIVGVKSSSRFNNI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MVLVKLLVIFIFIAVAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GVGAIAGLTTVMLVLFYGLTRVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMERPFKTPFMPYVPILGIISCFY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC
>Mature Secondary Structure
MDLFRKKDIKGSLDNESHLAKCLSVFDLTFLGVGAIIGAGIFVLTGIVAATISGPAVIFS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
YVVAGFACAFAALSYAELAASIGGCGSAYGYAYAGFGELIAWIVGWDLLLEYSIAVSAVS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGWSGYANDFLMALKIFIPANLLHGPADGGDLNILAILIIAVLTTLLIVGVKSSSRFNNI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MVLVKLLVIFIFIAVAFGEVKVENWSSFMPYGWAGVMKGASIIFFAYVGFDAVSTAAEEA
HHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
INPQRDLPIGIIASLAICTVIYILVSGLLTGIAHYTTLNVSSPISHVLLVLGYKTAAGLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GVGAIAGLTTVMLVLFYGLTRVFLAMSRDGLLPRFLSKTNEHTKTPIRIILLCGILMASL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ASVTPIGTLAELVNIGTLFAFIVVCGGVLYLRRTHPDMERPFKTPFMPYVPILGIISCFY
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LILNLPWVTILRFIIWMLVGIAVYFAFSRTNSALSVEGDCAAE
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]