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The map label for this gene is mpg

Identifier: 148285171

GI number: 148285171

Start: 2115985

End: 2116521

Strand: Direct

Name: mpg

Synonym: OTBS_2169

Alternate gene names: NA

Gene position: 2115985-2116521 (Clockwise)

Preceding gene: 148285170

Following gene: 148285172

Centisome position: 99.48

GC content: 29.8

Gene sequence:

>537_bases
ATGGTTTTAGGTAGAGAATTTTTTTTGCAGGATACAAATATAGTTAGTACTAATTTGATTGGTAAGCTGTTATGTTATAA
GAATTTCTGTGGTATTATTACTGAGACAGAAAGCTATATTGGACAAGATGATCCTGCTTGTCATGCTGCTAAAGGTATGA
CAAAAAGAACTAAAATTATGTTTGGGCAGGCTGGATTTAGTTATGTATACTTTATCTATGGTATGTACTATTGTCTAAAT
ATTGTTACTGAGGCTTTAAATTTTCCAGCTGCCACTTTAATTAGAGGAATAAAATTAATTCATCCTCCATATACCCATCT
TAATGGGCCAGGTAAAGTTTGCAAATTTTTAGGTATTAATTTAACTCATAATGCTATCGATATTACTTTATCAAAAGAAT
TATACATTAAGGACATAAGCTGCACATTAAATTATATATCTACACCTAGAATAGGTATTTCTAAGGGATTAAATAAAATG
TGGCGCTATGTTATTACTGATAAAGAATTTCCTTCAAATATTTTCCTACCTTCTTAG

Upstream 100 bases:

>100_bases
AAGAAAAATACTCAATCTAAAATAAATGTCGCTTCTGAAAAAAATGAGGAAGCTGCGGCAGGATAAATAAATTTTGTTTT
CTTGAAATAGAAAAGACCAA

Downstream 100 bases:

>100_bases
AAGTGATATATCGAGATGGTTGAAATAAAATTAGGAAATCGAAGTGCAACTAAAGCTTTTGCTCAGCACTTAGCTGTAAA
TTTGAAGCCAGGATCAATAG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MVLGREFFLQDTNIVSTNLIGKLLCYKNFCGIITETESYIGQDDPACHAAKGMTKRTKIMFGQAGFSYVYFIYGMYYCLN
IVTEALNFPAATLIRGIKLIHPPYTHLNGPGKVCKFLGINLTHNAIDITLSKELYIKDISCTLNYISTPRIGISKGLNKM
WRYVITDKEFPSNIFLPS

Sequences:

>Translated_178_residues
MVLGREFFLQDTNIVSTNLIGKLLCYKNFCGIITETESYIGQDDPACHAAKGMTKRTKIMFGQAGFSYVYFIYGMYYCLN
IVTEALNFPAATLIRGIKLIHPPYTHLNGPGKVCKFLGINLTHNAIDITLSKELYIKDISCTLNYISTPRIGISKGLNKM
WRYVITDKEFPSNIFLPS
>Mature_178_residues
MVLGREFFLQDTNIVSTNLIGKLLCYKNFCGIITETESYIGQDDPACHAAKGMTKRTKIMFGQAGFSYVYFIYGMYYCLN
IVTEALNFPAATLIRGIKLIHPPYTHLNGPGKVCKFLGINLTHNAIDITLSKELYIKDISCTLNYISTPRIGISKGLNKM
WRYVITDKEFPSNIFLPS

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=162, Percent_Identity=29.0123456790123, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI62632771, Length=162, Percent_Identity=29.0123456790123, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI62632765, Length=162, Percent_Identity=29.0123456790123, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 20085; Mature: 20085

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGREFFLQDTNIVSTNLIGKLLCYKNFCGIITETESYIGQDDPACHAAKGMTKRTKIM
CCCCCHHEECCCCCHHHHHHHHHHHHHHHCCEEECCHHHCCCCCCCHHHHCCCCHHHEEE
FGQAGFSYVYFIYGMYYCLNIVTEALNFPAATLIRGIKLIHPPYTHLNGPGKVCKFLGIN
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
LTHNAIDITLSKELYIKDISCTLNYISTPRIGISKGLNKMWRYVITDKEFPSNIFLPS
EECCEEEEEEECEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVLGREFFLQDTNIVSTNLIGKLLCYKNFCGIITETESYIGQDDPACHAAKGMTKRTKIM
CCCCCHHEECCCCCHHHHHHHHHHHHHHHCCEEECCHHHCCCCCCCHHHHCCCCHHHEEE
FGQAGFSYVYFIYGMYYCLNIVTEALNFPAATLIRGIKLIHPPYTHLNGPGKVCKFLGIN
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
LTHNAIDITLSKELYIKDISCTLNYISTPRIGISKGLNKMWRYVITDKEFPSNIFLPS
EECCEEEEEEECEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA