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The map label for this gene is sdhB [H]

Identifier: 148284922

GI number: 148284922

Start: 1653107

End: 1653898

Strand: Direct

Name: sdhB [H]

Synonym: OTBS_1699

Alternate gene names: 148284922

Gene position: 1653107-1653898 (Clockwise)

Preceding gene: 148284921

Following gene: 148284923

Centisome position: 77.72

GC content: 34.72

Gene sequence:

>792_bases
ATGCAAATGGTAGAATTTAGATTACCACCAAATTCAAAAGTTAAAGTAGGTAAGCGCTATGTTGCTAAAGACAGCGTTAA
GCGAGTAAAAAGAGTAAGTGTTTATCGTTATAGTCCTGATACTGGCGATAATCCTCGTATAGATATCTTTGAAATTGATA
TGGAAAATTGCGGACCTATGGTGCTTGATGCATTAATTAAAATTAAAAATGAGATTGATCCTACATTGACTTTTAGAAGA
TCGTGTCGTGAAGGCATTTGTGGCAGCTGTTCAATGAATATTAATGGTACTAATGGGTTAGCTTGTATTAAGGCTATAAA
TGATATTAAAGGTGATGTTATAATATATCCATTACCGCATATGAGTGTAATAAAGGACTTAGTATCTGATATGACACATT
TTTATGCTCAATATCAATCGATAGAGCCTTGGTTAAAAGCAGAAACTATAGATATAACTAGCGGTGAGAGACTACAAACT
CCAGAAGATAGGGATAAGTTAGATGGTCTATATGAATGTATATTATGCGCTTGTTGTTCTACAGCTTGTCCAAGTTATTG
GTGGAATGCGGACAAATATCTAGGACCTGCAGTATTGTTGCAAGCATACCGTTGGATTATCGATTCTAGGGATGAATATG
CATCAGAAAGGCTAGATCAACTTGAAGACTCTTTTAAGCTGTATAGATGTCATACTATTATGAATTGTACAAAAACTTGC
CCAAAAGGATTAAACCCTGCAAAGGCAATTAGCGAAATTAAGAAAAAAATGTTTGAACGGCATGGAGTATAG

Upstream 100 bases:

>100_bases
TATAGAGACGTAGTATTAGATCCAAAAAATGATGAAATGATGTCTATAGTTCCTAAAAAGCGAGTATATTAACTAGTGAT
TAGCAAGTAATAAATGAGTC

Downstream 100 bases:

>100_bases
AAAGAAATACTTATAATAGAACAGAACTACTGTGGAAATAGATTTGTGCCACAAATATATATGTTGTTGGCTGTGCACGA
TGCAAGATTATGTATATAAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MQMVEFRLPPNSKVKVGKRYVAKDSVKRVKRVSVYRYSPDTGDNPRIDIFEIDMENCGPMVLDALIKIKNEIDPTLTFRR
SCREGICGSCSMNINGTNGLACIKAINDIKGDVIIYPLPHMSVIKDLVSDMTHFYAQYQSIEPWLKAETIDITSGERLQT
PEDRDKLDGLYECILCACCSTACPSYWWNADKYLGPAVLLQAYRWIIDSRDEYASERLDQLEDSFKLYRCHTIMNCTKTC
PKGLNPAKAISEIKKKMFERHGV

Sequences:

>Translated_263_residues
MQMVEFRLPPNSKVKVGKRYVAKDSVKRVKRVSVYRYSPDTGDNPRIDIFEIDMENCGPMVLDALIKIKNEIDPTLTFRR
SCREGICGSCSMNINGTNGLACIKAINDIKGDVIIYPLPHMSVIKDLVSDMTHFYAQYQSIEPWLKAETIDITSGERLQT
PEDRDKLDGLYECILCACCSTACPSYWWNADKYLGPAVLLQAYRWIIDSRDEYASERLDQLEDSFKLYRCHTIMNCTKTC
PKGLNPAKAISEIKKKMFERHGV
>Mature_263_residues
MQMVEFRLPPNSKVKVGKRYVAKDSVKRVKRVSVYRYSPDTGDNPRIDIFEIDMENCGPMVLDALIKIKNEIDPTLTFRR
SCREGICGSCSMNINGTNGLACIKAINDIKGDVIIYPLPHMSVIKDLVSDMTHFYAQYQSIEPWLKAETIDITSGERLQT
PEDRDKLDGLYECILCACCSTACPSYWWNADKYLGPAVLLQAYRWIIDSRDEYASERLDQLEDSFKLYRCHTIMNCTKTC
PKGLNPAKAISEIKKKMFERHGV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=240, Percent_Identity=66.25, Blast_Score=341, Evalue=3e-94,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=55.5555555555556, Blast_Score=276, Evalue=8e-76,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.9285714285714, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=236, Percent_Identity=65.6779661016949, Blast_Score=333, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=62.0689655172414, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17137106, Length=260, Percent_Identity=60.3846153846154, Blast_Score=338, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643156, Length=231, Percent_Identity=63.6363636363636, Blast_Score=322, Evalue=1e-88,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30058; Mature: 30058

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMVEFRLPPNSKVKVGKRYVAKDSVKRVKRVSVYRYSPDTGDNPRIDIFEIDMENCGPM
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEECHHCCCHH
VLDALIKIKNEIDPTLTFRRSCREGICGSCSMNINGTNGLACIKAINDIKGDVIIYPLPH
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCC
MSVIKDLVSDMTHFYAQYQSIEPWLKAETIDITSGERLQTPEDRDKLDGLYECILCACCS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TACPSYWWNADKYLGPAVLLQAYRWIIDSRDEYASERLDQLEDSFKLYRCHTIMNCTKTC
HCCCCHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKGLNPAKAISEIKKKMFERHGV
CCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQMVEFRLPPNSKVKVGKRYVAKDSVKRVKRVSVYRYSPDTGDNPRIDIFEIDMENCGPM
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEECHHCCCHH
VLDALIKIKNEIDPTLTFRRSCREGICGSCSMNINGTNGLACIKAINDIKGDVIIYPLPH
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEEECCC
MSVIKDLVSDMTHFYAQYQSIEPWLKAETIDITSGERLQTPEDRDKLDGLYECILCACCS
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TACPSYWWNADKYLGPAVLLQAYRWIIDSRDEYASERLDQLEDSFKLYRCHTIMNCTKTC
HCCCCHHCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKGLNPAKAISEIKKKMFERHGV
CCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA