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The map label for this gene is ywlC [H]

Identifier: 148284357

GI number: 148284357

Start: 584546

End: 585514

Strand: Direct

Name: ywlC [H]

Synonym: OTBS_0605

Alternate gene names: 148284357

Gene position: 584546-585514 (Clockwise)

Preceding gene: 148284356

Following gene: 148284359

Centisome position: 27.48

GC content: 34.47

Gene sequence:

>969_bases
ATGTTAGCAAATATGAACAGTAATAATAATGATATAAATGTTGCTGCACAATTTATTGAACAAGGGAAATTAGTTATATT
CCCTACTGAAACAGTGTATGGCATAGGAGCTGATGCAACTAATGACAATGCTTGTCAAAGCATTTATAAAATCAAAAACA
GACCAATGAATAATCCATTAATTATTCATGTCAGCAATATACAAGCTGCTCAAACTATAGGCATATTTAACAATCTTGCT
ATTAAACTAGCAACCTTATGGCCAGGCCCAATTAGCTTAGTTGTACCACTTAATCAATCAGCAGGAATTAGCAGAACAGC
AACAGCAAATCTTGATACTGTAGCAATTAGAATTCCATCTCATAAGGTAGCTCTCATGTTGCTACAGTTAACACAAAAAC
CTATAGCTGCTCCAAGCGCAAACCCATCAGGCTATCTCAGCCCTACTACCTATCAACATGCCAATATCCATTTCCAAAAT
TCTCCAGACATATTCATTCTTAAGGGCGCTCAATCAACTTATGGATTAGAATCTACTATAATTGATACTACTGCTGATAG
ACCAACAATATTACGCCATGGATTCATTACAACAGAAATAATAAAGACTATTACTGGGCAAAACCCTATTATAGCAGAAA
AACATAACAAGCTTTTAAAAGCTCCAGGAATGATGTTAAAGCATTATTCTCCTATTACTAAAATTAGGTTAAATGCAACA
AAGCTTCTTCCAAAAGAAGTAGGATTAAATTATGGGCCTAATACTCTAACTGGAAAATACTGCCTAAATCTTAGCCCAAA
CAGTAATTTAATGAATGCAGCAGCAAACTTATATCATATGCTTCATCAACTTGACAACTATGCACAAAATCCTATCAATG
AGGTTGAGACTATCGCTATAGCTCAAATACCAAATATAGGCATAGGAATTGCTATCAATGACAAGCTTAATCGCGCAAGC
TCATATTAA

Upstream 100 bases:

>100_bases
ACTACTGATCAGTATCTTACTGATACTCGCAAGCTTATATTACAATATGTAGTACAGTTTTGCAATAATATAGCACCATT
TGACAAAGTAATAAAACATT

Downstream 100 bases:

>100_bases
CCCCAGAATAAGACAAGAGAAAGTATAAAAGGTATAGAATAAAAGATATACAAAGATAAAATGTTGAGTTACAAAGAAAA
TTTAAATAAAAATAAAATAA

Product: putative translation factor protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLANMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQSIYKIKNRPMNNPLIIHVSNIQAAQTIGIFNNLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPSHKVALMLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPDIFILKGAQSTYGLESTIIDTTADRPTILRHGFITTEIIKTITGQNPIIAEKHNKLLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAS
SY

Sequences:

>Translated_322_residues
MLANMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQSIYKIKNRPMNNPLIIHVSNIQAAQTIGIFNNLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPSHKVALMLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPDIFILKGAQSTYGLESTIIDTTADRPTILRHGFITTEIIKTITGQNPIIAEKHNKLLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAS
SY
>Mature_322_residues
MLANMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQSIYKIKNRPMNNPLIIHVSNIQAAQTIGIFNNLA
IKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPSHKVALMLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQN
SPDIFILKGAQSTYGLESTIIDTTADRPTILRHGFITTEIIKTITGQNPIIAEKHNKLLKAPGMMLKHYSPITKIRLNAT
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAIAQIPNIGIGIAINDKLNRAS
SY

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=167, Percent_Identity=26.9461077844311, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081864, Length=185, Percent_Identity=22.1621621621622, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=247, Percent_Identity=38.0566801619433, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI78707274, Length=144, Percent_Identity=34.7222222222222, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35034; Mature: 35034

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQSIYKIKNRPMNNPL
CCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCE
IIHVSNIQAAQTIGIFNNLAIKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPS
EEEECCCCCHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCEEEEEEECC
HKVALMLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQNSPDIFILKGAQSTYGLESTI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCEE
IDTTADRPTILRHGFITTEIIKTITGQNPIIAEKHNKLLKAPGMMLKHYSPITKIRLNAT
EECCCCCCEEEECCCHHHHHHHHHCCCCCEEEHHHCHHHHCCCHHHHHCCCCEEEEECHH
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAI
HHCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEE
AQIPNIGIGIAINDKLNRASSY
EECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLANMNSNNNDINVAAQFIEQGKLVIFPTETVYGIGADATNDNACQSIYKIKNRPMNNPL
CCCCCCCCCCCHHHHHHHHHCCCEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCE
IIHVSNIQAAQTIGIFNNLAIKLATLWPGPISLVVPLNQSAGISRTATANLDTVAIRIPS
EEEECCCCCHHHHHHHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCEEEEEEECC
HKVALMLLQLTQKPIAAPSANPSGYLSPTTYQHANIHFQNSPDIFILKGAQSTYGLESTI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCCCCCCCCEE
IDTTADRPTILRHGFITTEIIKTITGQNPIIAEKHNKLLKAPGMMLKHYSPITKIRLNAT
EECCCCCCEEEECCCHHHHHHHHHCCCCCEEEHHHCHHHHCCCHHHHHCCCCEEEEECHH
KLLPKEVGLNYGPNTLTGKYCLNLSPNSNLMNAAANLYHMLHQLDNYAQNPINEVETIAI
HHCHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEE
AQIPNIGIGIAINDKLNRASSY
EECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]