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The map label for this gene is iscA [C]

Identifier: 148284333

GI number: 148284333

Start: 543163

End: 543507

Strand: Direct

Name: iscA [C]

Synonym: OTBS_0572

Alternate gene names: 148284333

Gene position: 543163-543507 (Clockwise)

Preceding gene: 148284330

Following gene: 148284336

Centisome position: 25.54

GC content: 31.3

Gene sequence:

>345_bases
ATGAGTAACTCGAAATTTAATATCACAATAAGTGATACAGTATATAAGAGAATTCATGAATTAAACGAAGAAGCAAATGA
ACAACAGCCTCTTATGTTAAGAATTAGAGTTGATGCGGGTGGATGTTCAGGTTTTATTTATGAGTATGATCTTGTTATGG
AATATGAACCAGGGGATTTTATAGCTGAGAAAGATAATGCTATAGTAGTAATTGATTCATTATCACAAAATTTTATTAAT
GGTGCTATTATTGAGTATATAGAAGAGTTAGGACGCTCATATTTTAAAATTACTAATCCAGCAGCTCAAGCTAAATGTGG
CTGTGGTAACTCTTTTGCACTGTAA

Upstream 100 bases:

>100_bases
TATAAACAAAGCTACCACTATTATTAAAAAATAACATTATTAATCTTTATATCAATACAAAATTAACTATAATAATTGCC
AACATAAAACAATAGAAAGA

Downstream 100 bases:

>100_bases
TTACACTAAAGTTTGATTATTTGATTTTATAGCTTTGATACCAGCTAAACGTTTAATTGTATGTATTTTACCTAATATTG
GAATAACTTCAAATATACTA

Product: iron-binding protein IscA/HesB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSNSKFNITISDTVYKRIHELNEEANEQQPLMLRIRVDAGGCSGFIYEYDLVMEYEPGDFIAEKDNAIVVIDSLSQNFIN
GAIIEYIEELGRSYFKITNPAAQAKCGCGNSFAL

Sequences:

>Translated_114_residues
MSNSKFNITISDTVYKRIHELNEEANEQQPLMLRIRVDAGGCSGFIYEYDLVMEYEPGDFIAEKDNAIVVIDSLSQNFIN
GAIIEYIEELGRSYFKITNPAAQAKCGCGNSFAL
>Mature_113_residues
SNSKFNITISDTVYKRIHELNEEANEQQPLMLRIRVDAGGCSGFIYEYDLVMEYEPGDFIAEKDNAIVVIDSLSQNFING
AIIEYIEELGRSYFKITNPAAQAKCGCGNSFAL

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=109, Percent_Identity=38.5321100917431, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786351, Length=91, Percent_Identity=39.5604395604396, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=72, Evalue=6e-15,
Organism=Escherichia coli, GI1787974, Length=110, Percent_Identity=33.6363636363636, Blast_Score=64, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71998452, Length=109, Percent_Identity=34.8623853211009, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325324, Length=129, Percent_Identity=31.0077519379845, Blast_Score=63, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323001, Length=109, Percent_Identity=33.9449541284404, Blast_Score=61, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649697, Length=114, Percent_Identity=34.2105263157895, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12783; Mature: 12651

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSKFNITISDTVYKRIHELNEEANEQQPLMLRIRVDAGGCSGFIYEYDLVMEYEPGDF
CCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCE
IAEKDNAIVVIDSLSQNFINGAIIEYIEELGRSYFKITNPAAQAKCGCGNSFAL
EECCCCEEEEEECCCCCCCCHHHHHHHHHHCHHHEEECCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
SNSKFNITISDTVYKRIHELNEEANEQQPLMLRIRVDAGGCSGFIYEYDLVMEYEPGDF
CCCEEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCE
IAEKDNAIVVIDSLSQNFINGAIIEYIEELGRSYFKITNPAAQAKCGCGNSFAL
EECCCCEEEEEECCCCCCCCHHHHHHHHHHCHHHEEECCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]