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The map label for this gene is ubiA [H]

Identifier: 148284149

GI number: 148284149

Start: 269063

End: 269941

Strand: Direct

Name: ubiA [H]

Synonym: OTBS_0274

Alternate gene names: 148284149

Gene position: 269063-269941 (Clockwise)

Preceding gene: 148284146

Following gene: 148284152

Centisome position: 12.65

GC content: 28.67

Gene sequence:

>879_bases
ATGACTACTTTTTTAAGAATAATATACCAATTTAATCTTTTAATAAAGCTATCTCGTTTAAACAATCCAGTTGGTATTTT
TTTGTTATTTTTTCCGTGTTGTTTTGGAATAGGATTAGTTTCATTAGAACAAGTCAAATATAACAGTTTAGTTATTCTTT
TCCTTGGTAGTATATTAATGCGTAGTTTTGGCTGCATAGTAAATGATATTGTAGATAAAGATATTGACTGTAGAGTTGCT
AGAACTAAACTTCGCCCACTTGCAAACAATCAAATAACAGTTACTAATGCAATTATATATCTAATGGTTATCTCAATGGT
TGCGTTAATGCTACTAATGCAACTATCAAATTTAGCTATTTTTTTAGCTATTTTAGCATCAACATTAATCTTTATTTACC
CATTTATGAAGCGTATTACTTATTATCCTCAAGTTGTTTTAGGTATTATTTTTAATTCTGGCGCTTTGATATCTTATGCT
AACGTCACCAATAATTTAACTATAGCAAGTGTTGTAATGTATATTGGCTGTATTTTTTGGACTATTGGTTATGATACAAT
CTATGCCTTTGCAGATGCTGCTGATGATGAAAAGATAAAGGTTAAATCTTTAGCTTTAGTGCTTAAAAATAACAAGTATA
AGCTATGGATTTTAGCATCACTATATCTTACATTTATCAGTATGTTCGTTGAATCGATATTATTATCTGCATTTAAATTA
TCAATTTTTGCTGTGCTGTTTATAGTTGCTGCTACAGCATTATTAATGTGGCAAATTGTTACATTAGATGTTACTCAACC
ACTGAATTGTTTAACACGGTTTAAAGCAAATACTATTGTCGGGTTGTTACTTTTTATAGCTATGATTTTGCTACAATAA

Upstream 100 bases:

>100_bases
TTTTTCTGCCAATCATCTTGCCACTTTGGTTCATTTTCTAAATAGTTGTAATTTGCTGACAATTCGGCCATAATTTTCCT
TTACATTTGATAGATAATAA

Downstream 100 bases:

>100_bases
CACAAGTTTGATATAGAAATAGGCTTTGTTCAAAAGTTACTTCAAAATTGCTTTTTTAAAGCCAATGCCAAAGCTTTATT
CCTAATGACAATAATAAAAG

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVILFLGSILMRSFGCIVNDIVDKDIDCRVA
RTKLRPLANNQITVTNAIIYLMVISMVALMLLMQLSNLAIFLAILASTLIFIYPFMKRITYYPQVVLGIIFNSGALISYA
NVTNNLTIASVVMYIGCIFWTIGYDTIYAFADAADDEKIKVKSLALVLKNNKYKLWILASLYLTFISMFVESILLSAFKL
SIFAVLFIVAATALLMWQIVTLDVTQPLNCLTRFKANTIVGLLLFIAMILLQ

Sequences:

>Translated_292_residues
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVILFLGSILMRSFGCIVNDIVDKDIDCRVA
RTKLRPLANNQITVTNAIIYLMVISMVALMLLMQLSNLAIFLAILASTLIFIYPFMKRITYYPQVVLGIIFNSGALISYA
NVTNNLTIASVVMYIGCIFWTIGYDTIYAFADAADDEKIKVKSLALVLKNNKYKLWILASLYLTFISMFVESILLSAFKL
SIFAVLFIVAATALLMWQIVTLDVTQPLNCLTRFKANTIVGLLLFIAMILLQ
>Mature_291_residues
TTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVILFLGSILMRSFGCIVNDIVDKDIDCRVAR
TKLRPLANNQITVTNAIIYLMVISMVALMLLMQLSNLAIFLAILASTLIFIYPFMKRITYYPQVVLGIIFNSGALISYAN
VTNNLTIASVVMYIGCIFWTIGYDTIYAFADAADDEKIKVKSLALVLKNNKYKLWILASLYLTFISMFVESILLSAFKLS
IFAVLFIVAATALLMWQIVTLDVTQPLNCLTRFKANTIVGLLLFIAMILLQ

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=34.4086021505376, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=30.9090909090909, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17553718, Length=278, Percent_Identity=37.410071942446, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=36.2007168458781, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17553720, Length=339, Percent_Identity=29.4985250737463, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=39.4160583941606, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=38.9705882352941, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=274, Percent_Identity=30.2919708029197, Blast_Score=133, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=37.6344086021505, Blast_Score=190, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 32877; Mature: 32746

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVILFLGSILM
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFGCIVNDIVDKDIDCRVARTKLRPLANNQITVTNAIIYLMVISMVALMLLMQLSNLAI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLAILASTLIFIYPFMKRITYYPQVVLGIIFNSGALISYANVTNNLTIASVVMYIGCIFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TIGYDTIYAFADAADDEKIKVKSLALVLKNNKYKLWILASLYLTFISMFVESILLSAFKL
HHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
SIFAVLFIVAATALLMWQIVTLDVTQPLNCLTRFKANTIVGLLLFIAMILLQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTFLRIIYQFNLLIKLSRLNNPVGIFLLFFPCCFGIGLVSLEQVKYNSLVILFLGSILM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSFGCIVNDIVDKDIDCRVARTKLRPLANNQITVTNAIIYLMVISMVALMLLMQLSNLAI
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLAILASTLIFIYPFMKRITYYPQVVLGIIFNSGALISYANVTNNLTIASVVMYIGCIFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
TIGYDTIYAFADAADDEKIKVKSLALVLKNNKYKLWILASLYLTFISMFVESILLSAFKL
HHHHHHHHHHHCCCCCCHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
SIFAVLFIVAATALLMWQIVTLDVTQPLNCLTRFKANTIVGLLLFIAMILLQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA