Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 148261169

GI number: 148261169

Start: 2404958

End: 2405746

Strand: Reverse

Name: ompR [H]

Synonym: Acry_2179

Alternate gene names: 148261169

Gene position: 2405746-2404958 (Counterclockwise)

Preceding gene: 148261174

Following gene: 148261168

Centisome position: 70.98

GC content: 68.44

Gene sequence:

>789_bases
ATGATCATTTTGCGTAAGGAAATGCAACGGCGCGCCCAAAGTGAAACGATCCCGGCTATTGTAACAGCCATGGACATCAT
GCCGCACATCCTCGTGGTCGACGATGACCGCGAAATCCGTGAACTGCTCGCCCGCTTTCTCGAACGCCAGCGCTTCCGCG
TCACCGCCGTGCGGGATGCGCGCGAGGCGCGGCGGGCCTACCTCAACGGCCATTACCAGCTCGTCGTGCTCGATCTCATG
CTGCCCGGCGAATCGGGGATCGATTTCGCTCGCTGGCTGCGCGGGGAATCGCAGGTGCCGATCATCATGCTCACGGCGCT
GGGCGAGGAGCCGGACCGGATCATCGGCCTCGAACTCGGCGCCGACGACTATGTGACGAAGCCGTTCAACCCGCGCGAGC
TGGTGGCGCGGATCCGCGCGGTGCTGCGCCGCGTCGGCGAGAACGAGACCCCGGGCCGCGAAAGCTCGGCGCGGCTCTAC
CGCTTCGCCGGGTGGGTGCTGGAGACGTCGCGGCGCCGGCTGCTCGACCCGCACGGGGTCGAGGTGCCGCTGACCGGCGG
GGAATACGACCTGCTGCTCGCCCTGCTCGACCGGCCGAACCGGGTGCTGACCCGCGACATGCTGCTCGACCTGCTGCGCG
GGCGGCAGGCGGGGCCGTTCGACCGGGCGATCGACGTCGCGATCTCGCGGCTGCGGCGCAAGCTCGAGGATGACGGGCGG
CACGCGCAGATCATCAAGACGGTGCGCGGCGGCGGCTATGTGCTGGCGGTGCCGGTCGAGCGTTCATGA

Upstream 100 bases:

>100_bases
CGTAACCCCCGACGGGAGGCAGAGGCACGTGCGTTGCTGCGTGGAGCGCGACATAGGGCCATCACCCCGGGGGCGCAAGT
AAAATCTTGGACGCCGGGGC

Downstream 100 bases:

>100_bases
CCCTCGGCCGGATCTGGGCACGGCTGAAATTCTGGCCTTCCAGCCTCGCCTGGCGCACCGGGCTCGTTCTGCTGCTCGGG
TTTTCGCTGATCCAGGCCAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MIILRKEMQRRAQSETIPAIVTAMDIMPHILVVDDDREIRELLARFLERQRFRVTAVRDAREARRAYLNGHYQLVVLDLM
LPGESGIDFARWLRGESQVPIIMLTALGEEPDRIIGLELGADDYVTKPFNPRELVARIRAVLRRVGENETPGRESSARLY
RFAGWVLETSRRRLLDPHGVEVPLTGGEYDLLLALLDRPNRVLTRDMLLDLLRGRQAGPFDRAIDVAISRLRRKLEDDGR
HAQIIKTVRGGGYVLAVPVERS

Sequences:

>Translated_262_residues
MIILRKEMQRRAQSETIPAIVTAMDIMPHILVVDDDREIRELLARFLERQRFRVTAVRDAREARRAYLNGHYQLVVLDLM
LPGESGIDFARWLRGESQVPIIMLTALGEEPDRIIGLELGADDYVTKPFNPRELVARIRAVLRRVGENETPGRESSARLY
RFAGWVLETSRRRLLDPHGVEVPLTGGEYDLLLALLDRPNRVLTRDMLLDLLRGRQAGPFDRAIDVAISRLRRKLEDDGR
HAQIIKTVRGGGYVLAVPVERS
>Mature_262_residues
MIILRKEMQRRAQSETIPAIVTAMDIMPHILVVDDDREIRELLARFLERQRFRVTAVRDAREARRAYLNGHYQLVVLDLM
LPGESGIDFARWLRGESQVPIIMLTALGEEPDRIIGLELGADDYVTKPFNPRELVARIRAVLRRVGENETPGRESSARLY
RFAGWVLETSRRRLLDPHGVEVPLTGGEYDLLLALLDRPNRVLTRDMLLDLLRGRQAGPFDRAIDVAISRLRRKLEDDGR
HAQIIKTVRGGGYVLAVPVERS

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=50.4385964912281, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=37.1794871794872, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=43.4782608695652, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=41.4847161572052, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=37.4468085106383, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=36.5638766519824, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=35.2173913043478, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=34.1772151898734, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.0357142857143, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=33.6244541484716, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=36.0869565217391, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790552, Length=236, Percent_Identity=35.5932203389831, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.7510917030568, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=33.7719298245614, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=32.1428571428571, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29959; Mature: 29959

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILRKEMQRRAQSETIPAIVTAMDIMPHILVVDDDREIRELLARFLERQRFRVTAVRDA
CEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHEEHHHHHHH
REARRAYLNGHYQLVVLDLMLPGESGIDFARWLRGESQVPIIMLTALGEEPDRIIGLELG
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEC
ADDYVTKPFNPRELVARIRAVLRRVGENETPGRESSARLYRFAGWVLETSRRRLLDPHGV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EVPLTGGEYDLLLALLDRPNRVLTRDMLLDLLRGRQAGPFDRAIDVAISRLRRKLEDDGR
EEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
HAQIIKTVRGGGYVLAVPVERS
HHHHHHHCCCCCEEEEEECCCC
>Mature Secondary Structure
MIILRKEMQRRAQSETIPAIVTAMDIMPHILVVDDDREIRELLARFLERQRFRVTAVRDA
CEEEHHHHHHHHHHCCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHEEHHHHHHH
REARRAYLNGHYQLVVLDLMLPGESGIDFARWLRGESQVPIIMLTALGEEPDRIIGLELG
HHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEC
ADDYVTKPFNPRELVARIRAVLRRVGENETPGRESSARLYRFAGWVLETSRRRLLDPHGV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
EVPLTGGEYDLLLALLDRPNRVLTRDMLLDLLRGRQAGPFDRAIDVAISRLRRKLEDDGR
EEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
HAQIIKTVRGGGYVLAVPVERS
HHHHHHHCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]