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The map label for this gene is ytfL [C]

Identifier: 148261136

GI number: 148261136

Start: 2367711

End: 2369003

Strand: Reverse

Name: ytfL [C]

Synonym: Acry_2145

Alternate gene names: 148261136

Gene position: 2369003-2367711 (Counterclockwise)

Preceding gene: 148261138

Following gene: 148261135

Centisome position: 69.9

GC content: 69.84

Gene sequence:

>1293_bases
ATGCACGTTGTTGTTCTGATACTGATTTTGACCTTGCTGATCCTGCTCAATGCCGGATTCGCCCTCGCCGAGATGGCGCT
GGTGTCGTCCCGCAAGGCGGCGCTCGCGCTGTTCGCCCGAAAAGGCGTGCGCGGCGCCGAGCGCGCGCGCCTGCTGGCCG
AGACGCCCGAGCGCTTCCTGCCCACGGTGCAGATCGGCATCACCGCGATCAGCGTGCTGACCGGCGTGGTGGGCGGGGCG
CAGCTCGCCCATTCGCTGGCGCCGGCGATCGCGCTGATCCGCCCGCTCGCCCCGCTCGCCGACACGATCGCGCTGGCGCT
CACCGTCGTCGGCGTCACGCTGCTCACCCTCGTCTTCGGCGAACTCGTGCCGAAGCAGCTCGCCTTGCGCAATGCCGAGC
GGATCGCCTGCCTCGTCGCCTGGCCGATCGACATGTTCGCCCGCGCCGCCTCGCCGCTGGTCTGGCTGCTGGGCTTCACC
TCCGACCTGGTGCTGCGCCTGTTCGGCCCGGTCGATCCGCACCGCCGGGCGATCAGCGAGGAGGAGCTGAAGGCCATCCT
CGCCGAGGGCACCGAATCCGGCATGCTCGAATACGAGGAGCGGGACATGATGGAGCGGGTCATGCGCCTCGCCGACAAGC
CGATCCGCGCGATCATGACGCCGCGGCAGGACATCGCCTGGCTCGACCGCACCGCCCCGCGCGGCCAGGTGATCTCCTCG
CTGAAGGCCGCGCCGCATTCCCGCTTCGTGGTCTGCGACCGCAGCATCGACAATGTGGTCGGCATCGTCCAGGCCAAGGA
CATCCTCGACCGGATGCTGGACGGCAAGGACATCTCGATCGCCACCGCGCTGCGCCAGCCGCTCGCCGTGCCGGACGCGA
TCTCCGCGCTCGATGCGCTGGAGCGCCTGAAATCCGACCCGCTCGGCGTCGCCTTCGTGCTCGACGAATATGGCAGCTTC
GAGGGCATGGTGACGGTGGGCGACCTGCTCGAGGCGATCGTCGGCGATGTCGAGGAGGCGGGCTATGGCGAGGCCGGCGA
ACCCGCGCCCGACCGCTACGAGCTCGACGGTCTCGAACCGATCGACGAGGTGGCGCACAAGTTCGGGCTGGAGAACCTGC
CCGCCCACGGCTCGTATCACACGCTGGGCGGCTTCCTGCTCGCCCTGCTCAAGCGGGTGCCGCGCCAGGGCGACGCGATC
GCCTTCGGCGGCTGGCGCTTCGAGGTGCTGGCGATGAACGGCCGCCGGGTGGAACTCGTGCGCGTCAGCCGCGATCCCAC
GGCCGTGCCGTGA

Upstream 100 bases:

>100_bases
TTCATGTCCTGCGCATCCGCTATGCTGCTGGATCGGAGATCGTTACGCCGGTGAAGCTCGGTTTCGTTGTCCTGGGTTCA
TGTCAGAACTGAAGTAAGGT

Downstream 100 bases:

>100_bases
AATTAGGCTTTCATTAAGTCCCGCCTGCTATGCGGGGTCGGTGATCCACGCTGCTAGGCCCAGCCTGTCAAGGGGAGCCC
GATCCATGAAACGCCATCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MHVVVLILILTLLILLNAGFALAEMALVSSRKAALALFARKGVRGAERARLLAETPERFLPTVQIGITAISVLTGVVGGA
QLAHSLAPAIALIRPLAPLADTIALALTVVGVTLLTLVFGELVPKQLALRNAERIACLVAWPIDMFARAASPLVWLLGFT
SDLVLRLFGPVDPHRRAISEEELKAILAEGTESGMLEYEERDMMERVMRLADKPIRAIMTPRQDIAWLDRTAPRGQVISS
LKAAPHSRFVVCDRSIDNVVGIVQAKDILDRMLDGKDISIATALRQPLAVPDAISALDALERLKSDPLGVAFVLDEYGSF
EGMVTVGDLLEAIVGDVEEAGYGEAGEPAPDRYELDGLEPIDEVAHKFGLENLPAHGSYHTLGGFLLALLKRVPRQGDAI
AFGGWRFEVLAMNGRRVELVRVSRDPTAVP

Sequences:

>Translated_430_residues
MHVVVLILILTLLILLNAGFALAEMALVSSRKAALALFARKGVRGAERARLLAETPERFLPTVQIGITAISVLTGVVGGA
QLAHSLAPAIALIRPLAPLADTIALALTVVGVTLLTLVFGELVPKQLALRNAERIACLVAWPIDMFARAASPLVWLLGFT
SDLVLRLFGPVDPHRRAISEEELKAILAEGTESGMLEYEERDMMERVMRLADKPIRAIMTPRQDIAWLDRTAPRGQVISS
LKAAPHSRFVVCDRSIDNVVGIVQAKDILDRMLDGKDISIATALRQPLAVPDAISALDALERLKSDPLGVAFVLDEYGSF
EGMVTVGDLLEAIVGDVEEAGYGEAGEPAPDRYELDGLEPIDEVAHKFGLENLPAHGSYHTLGGFLLALLKRVPRQGDAI
AFGGWRFEVLAMNGRRVELVRVSRDPTAVP
>Mature_430_residues
MHVVVLILILTLLILLNAGFALAEMALVSSRKAALALFARKGVRGAERARLLAETPERFLPTVQIGITAISVLTGVVGGA
QLAHSLAPAIALIRPLAPLADTIALALTVVGVTLLTLVFGELVPKQLALRNAERIACLVAWPIDMFARAASPLVWLLGFT
SDLVLRLFGPVDPHRRAISEEELKAILAEGTESGMLEYEERDMMERVMRLADKPIRAIMTPRQDIAWLDRTAPRGQVISS
LKAAPHSRFVVCDRSIDNVVGIVQAKDILDRMLDGKDISIATALRQPLAVPDAISALDALERLKSDPLGVAFVLDEYGSF
EGMVTVGDLLEAIVGDVEEAGYGEAGEPAPDRYELDGLEPIDEVAHKFGLENLPAHGSYHTLGGFLLALLKRVPRQGDAI
AFGGWRFEVLAMNGRRVELVRVSRDPTAVP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=380, Percent_Identity=27.3684210526316, Blast_Score=166, Evalue=4e-41,
Organism=Escherichia coli, GI1790664, Length=424, Percent_Identity=29.2452830188679, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI87082033, Length=325, Percent_Identity=29.2307692307692, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=25.8373205741627, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1788119, Length=269, Percent_Identity=28.6245353159851, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786879, Length=271, Percent_Identity=29.520295202952, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46448; Mature: 46448

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVVVLILILTLLILLNAGFALAEMALVSSRKAALALFARKGVRGAERARLLAETPERFL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHC
PTVQIGITAISVLTGVVGGAQLAHSLAPAIALIRPLAPLADTIALALTVVGVTLLTLVFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKQLALRNAERIACLVAWPIDMFARAASPLVWLLGFTSDLVLRLFGPVDPHRRAISE
HHHHHHHHHCCHHHEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCH
EELKAILAEGTESGMLEYEERDMMERVMRLADKPIRAIMTPRQDIAWLDRTAPRGQVISS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCHHHHHHH
LKAAPHSRFVVCDRSIDNVVGIVQAKDILDRMLDGKDISIATALRQPLAVPDAISALDAL
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
ERLKSDPLGVAFVLDEYGSFEGMVTVGDLLEAIVGDVEEAGYGEAGEPAPDRYELDGLEP
HHHCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCH
IDEVAHKFGLENLPAHGSYHTLGGFLLALLKRVPRQGDAIAFGGWRFEVLAMNGRRVELV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCEEEEE
RVSRDPTAVP
EECCCCCCCC
>Mature Secondary Structure
MHVVVLILILTLLILLNAGFALAEMALVSSRKAALALFARKGVRGAERARLLAETPERFL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHC
PTVQIGITAISVLTGVVGGAQLAHSLAPAIALIRPLAPLADTIALALTVVGVTLLTLVFG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKQLALRNAERIACLVAWPIDMFARAASPLVWLLGFTSDLVLRLFGPVDPHRRAISE
HHHHHHHHHCCHHHEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCH
EELKAILAEGTESGMLEYEERDMMERVMRLADKPIRAIMTPRQDIAWLDRTAPRGQVISS
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCHHHHHHH
LKAAPHSRFVVCDRSIDNVVGIVQAKDILDRMLDGKDISIATALRQPLAVPDAISALDAL
HHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHH
ERLKSDPLGVAFVLDEYGSFEGMVTVGDLLEAIVGDVEEAGYGEAGEPAPDRYELDGLEP
HHHCCCCCCEEEEECCCCCCCCEEEHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCH
IDEVAHKFGLENLPAHGSYHTLGGFLLALLKRVPRQGDAIAFGGWRFEVLAMNGRRVELV
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCEEEEE
RVSRDPTAVP
EECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]