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The map label for this gene is mcpA [H]

Identifier: 148261135

GI number: 148261135

Start: 2365893

End: 2367563

Strand: Reverse

Name: mcpA [H]

Synonym: Acry_2144

Alternate gene names: 148261135

Gene position: 2367563-2365893 (Counterclockwise)

Preceding gene: 148261136

Following gene: 148261128

Centisome position: 69.86

GC content: 70.5

Gene sequence:

>1671_bases
ATGGTCTGGATACTGGCCGGCATCGTCCTGGCCGCGGCCGGCGCCATCGCCGCCATTCTGCTCGGCGTCCGCCGCCGCAT
CTCCGCCCTCGCGCGGGATCTGAACGCCGTGGCGATCGCCGCGAGCGAGGCGCATCGCGACATGGTCGCGCAGAACGGGC
TCGACCGGAACATCGATGGCCTGCGCGCCCGTCTCGCGGCCCTCGGCCCGGCGCGCATCGAGAACGACGAACTCTGGTTC
GGCGCCTACCGCATCAATGGCGACGATCGTGTCGTCGACGAGATCAAGACGCAATACGGCGGCGCCGTGACCATCTTCAT
GCGCGACGTCCGGGTGGCCACGAATGTCCAGAAGCCGGACGGCACCCGCGCGGTCGGCACGAGACTCGCCCCCGGCCCGA
TCCACGATGCCGTGCTCGGCATGGGCAAGACCTATCGCGGCGAGGCTGAAATCCTCGGCGAACCCTATTTCGCCATCTAC
GAGCCGGTCATCGCCAACCACGAGACGATCGCGATCATCTTCGTCGGCGTCAGGAAGCTGGACCTGCCGGAGGGGACGGT
GACCGGCGATCCGCGCAGCATGGCCTGCATCCGCGCCGATCTCGATTCCCTGCGGAAGGTGCTCGCCGAGCAGGTCAGGA
CGGCCGGGGAAGCGATCGCCCTGCGGCAGCTTTCCGAGGATACGCGGCGCGCCCTCGATGCCGAGCGTGTCACGCGCGCC
CACCAGCAGGCGCACGCGATCGCCGCCCTCGGCACCGGCCTCGAGCGCCTCGCCGGCGGCGACCTGCTGTTCCGGCTCGA
CGAGAAGCTGGCCGCGGAATACGAAAAGCTCCGCACCGACTTCAACGGCGCGATCCGCCAGCTTCACGACGCGATGGCGA
TGATTGCCCGCAACGCCGACGCGGTGCGTTCGGGCGCGCAGGAAATCACCGCGGCGTCGGACGATCTGGCCCGCCGCACC
GAACAGCAGGCCGCGACGCTCGAACAGACGGCCGCGGCGCTGGAACAGATCACCGCCACCGTGCGGCGCACCGCCGCCGG
CACCGGCGAGGCCCGGAAACTGGTCGGCGACGCGCGCTCCGAGACCGATCATTCGGGCGAGATCGTGCAGCGCGCGGTCG
CGGCGATGAGCGCAATCGAGGCGTCATCCCGCCAGATCGGGCAGATCAGCGGGCTGATCGACGAAATTGCCTTCCAGACC
AACCTCCTCGCCCTGAATGCCGGCGTCGAGGCGGCGCGCGCGGGCGAGGCCGGCCGCGGCTTCGCCGTCGTCGCCACCGA
GGTCCGCGCCCTGGCCCAGCGCTCGGCCTCCGCCGCGCGCGAGATCCAGCAGCTCATCGCCACCTCGGATCGCGAGGTCG
GCGCCGGCGTCGAACTCGTGGGCGAAACCGGCGCCGCGCTCGAGCGCATCGCCCGGCAGGTCTCGGCGCTCAACGGCCTG
ATCGTCGACATCGCGGCCTCGTCGGAAGAACAGTCGACCGGGCTCGCCGAGGTCAACACCGCCGTCAACCAGATGGATCA
GGTGACCCAGCAAAACGCCGCCATGGTCGAGCAGACCACCGCGGCCAGCCACGGCATGTCGTCCGAAGCGGCGACCCTGG
CGCAGTTGCTCAGCCGGTTCCGCATCGCCGCCGGCGCCAACGTGGTGCGCCTGCCCGCAAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
ACGCTGCTAGGCCCAGCCTGTCAAGGGGAGCCCGATCCATGAAACGCCATCCCGTCAGGATTGTCGTCCCGTCCGCCGGC
CGGTCGCGGGGCCGGTGACG

Downstream 100 bases:

>100_bases
ACCGCGCGGGGTCCGCTCGCCGCCCGGCGGAAAGCCCGCCGGGTGCCGCCCTCACGCGTGGATCAGCGTGCCGATGCCGC
CTTCGGTGAACAGTTCCAGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MVWILAGIVLAAAGAIAAILLGVRRRISALARDLNAVAIAASEAHRDMVAQNGLDRNIDGLRARLAALGPARIENDELWF
GAYRINGDDRVVDEIKTQYGGAVTIFMRDVRVATNVQKPDGTRAVGTRLAPGPIHDAVLGMGKTYRGEAEILGEPYFAIY
EPVIANHETIAIIFVGVRKLDLPEGTVTGDPRSMACIRADLDSLRKVLAEQVRTAGEAIALRQLSEDTRRALDAERVTRA
HQQAHAIAALGTGLERLAGGDLLFRLDEKLAAEYEKLRTDFNGAIRQLHDAMAMIARNADAVRSGAQEITAASDDLARRT
EQQAATLEQTAAALEQITATVRRTAAGTGEARKLVGDARSETDHSGEIVQRAVAAMSAIEASSRQIGQISGLIDEIAFQT
NLLALNAGVEAARAGEAGRGFAVVATEVRALAQRSASAAREIQQLIATSDREVGAGVELVGETGAALERIARQVSALNGL
IVDIAASSEEQSTGLAEVNTAVNQMDQVTQQNAAMVEQTTAASHGMSSEAATLAQLLSRFRIAAGANVVRLPAKVA

Sequences:

>Translated_556_residues
MVWILAGIVLAAAGAIAAILLGVRRRISALARDLNAVAIAASEAHRDMVAQNGLDRNIDGLRARLAALGPARIENDELWF
GAYRINGDDRVVDEIKTQYGGAVTIFMRDVRVATNVQKPDGTRAVGTRLAPGPIHDAVLGMGKTYRGEAEILGEPYFAIY
EPVIANHETIAIIFVGVRKLDLPEGTVTGDPRSMACIRADLDSLRKVLAEQVRTAGEAIALRQLSEDTRRALDAERVTRA
HQQAHAIAALGTGLERLAGGDLLFRLDEKLAAEYEKLRTDFNGAIRQLHDAMAMIARNADAVRSGAQEITAASDDLARRT
EQQAATLEQTAAALEQITATVRRTAAGTGEARKLVGDARSETDHSGEIVQRAVAAMSAIEASSRQIGQISGLIDEIAFQT
NLLALNAGVEAARAGEAGRGFAVVATEVRALAQRSASAAREIQQLIATSDREVGAGVELVGETGAALERIARQVSALNGL
IVDIAASSEEQSTGLAEVNTAVNQMDQVTQQNAAMVEQTTAASHGMSSEAATLAQLLSRFRIAAGANVVRLPAKVA
>Mature_556_residues
MVWILAGIVLAAAGAIAAILLGVRRRISALARDLNAVAIAASEAHRDMVAQNGLDRNIDGLRARLAALGPARIENDELWF
GAYRINGDDRVVDEIKTQYGGAVTIFMRDVRVATNVQKPDGTRAVGTRLAPGPIHDAVLGMGKTYRGEAEILGEPYFAIY
EPVIANHETIAIIFVGVRKLDLPEGTVTGDPRSMACIRADLDSLRKVLAEQVRTAGEAIALRQLSEDTRRALDAERVTRA
HQQAHAIAALGTGLERLAGGDLLFRLDEKLAAEYEKLRTDFNGAIRQLHDAMAMIARNADAVRSGAQEITAASDDLARRT
EQQAATLEQTAAALEQITATVRRTAAGTGEARKLVGDARSETDHSGEIVQRAVAAMSAIEASSRQIGQISGLIDEIAFQT
NLLALNAGVEAARAGEAGRGFAVVATEVRALAQRSASAAREIQQLIATSDREVGAGVELVGETGAALERIARQVSALNGL
IVDIAASSEEQSTGLAEVNTAVNQMDQVTQQNAAMVEQTTAASHGMSSEAATLAQLLSRFRIAAGANVVRLPAKVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=293, Percent_Identity=42.6621160409556, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=43.2786885245902, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367378, Length=289, Percent_Identity=44.636678200692, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788194, Length=302, Percent_Identity=41.7218543046358, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI1789453, Length=229, Percent_Identity=40.6113537117904, Blast_Score=161, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58799; Mature: 58799

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWILAGIVLAAAGAIAAILLGVRRRISALARDLNAVAIAASEAHRDMVAQNGLDRNIDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCHHH
LRARLAALGPARIENDELWFGAYRINGDDRVVDEIKTQYGGAVTIFMRDVRVATNVQKPD
HHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCEEEEEEEHHHHHHCCCCCC
GTRAVGTRLAPGPIHDAVLGMGKTYRGEAEILGEPYFAIYEPVIANHETIAIIFVGVRKL
CCHHHCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEEECEEE
DLPEGTVTGDPRSMACIRADLDSLRKVLAEQVRTAGEAIALRQLSEDTRRALDAERVTRA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQQAHAIAALGTGLERLAGGDLLFRLDEKLAAEYEKLRTDFNGAIRQLHDAMAMIARNAD
HHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVRSGAQEITAASDDLARRTEQQAATLEQTAAALEQITATVRRTAAGTGEARKLVGDARS
HHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
ETDHSGEIVQRAVAAMSAIEASSRQIGQISGLIDEIAFQTNLLALNAGVEAARAGEAGRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCC
FAVVATEVRALAQRSASAAREIQQLIATSDREVGAGVELVGETGAALERIARQVSALNGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCE
IVDIAASSEEQSTGLAEVNTAVNQMDQVTQQNAAMVEQTTAASHGMSSEAATLAQLLSRF
EEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RIAAGANVVRLPAKVA
HHHCCCCEEECCCCCC
>Mature Secondary Structure
MVWILAGIVLAAAGAIAAILLGVRRRISALARDLNAVAIAASEAHRDMVAQNGLDRNIDG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHCCCCCCHHH
LRARLAALGPARIENDELWFGAYRINGDDRVVDEIKTQYGGAVTIFMRDVRVATNVQKPD
HHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCEEEEEEEHHHHHHCCCCCC
GTRAVGTRLAPGPIHDAVLGMGKTYRGEAEILGEPYFAIYEPVIANHETIAIIFVGVRKL
CCHHHCCCCCCCCHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEEECEEE
DLPEGTVTGDPRSMACIRADLDSLRKVLAEQVRTAGEAIALRQLSEDTRRALDAERVTRA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQQAHAIAALGTGLERLAGGDLLFRLDEKLAAEYEKLRTDFNGAIRQLHDAMAMIARNAD
HHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVRSGAQEITAASDDLARRTEQQAATLEQTAAALEQITATVRRTAAGTGEARKLVGDARS
HHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
ETDHSGEIVQRAVAAMSAIEASSRQIGQISGLIDEIAFQTNLLALNAGVEAARAGEAGRG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCC
FAVVATEVRALAQRSASAAREIQQLIATSDREVGAGVELVGETGAALERIARQVSALNGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCE
IVDIAASSEEQSTGLAEVNTAVNQMDQVTQQNAAMVEQTTAASHGMSSEAATLAQLLSRF
EEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RIAAGANVVRLPAKVA
HHHCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]