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The map label for this gene is ribD [H]

Identifier: 148261112

GI number: 148261112

Start: 2348494

End: 2349585

Strand: Reverse

Name: ribD [H]

Synonym: Acry_2121

Alternate gene names: 148261112

Gene position: 2349585-2348494 (Counterclockwise)

Preceding gene: 148261113

Following gene: 148261111

Centisome position: 69.33

GC content: 74.27

Gene sequence:

>1092_bases
ATGGACGATCTCGCGCATATGCGGACGGCCCTCGCGCTCGCACGGCGCGGCCTGGGCGAGACCGCGCCGAATCCGACCGT
CGGCTGCGTGATCGTGCGCGGCGGGCGGGTGGTCGGGCGTGGCCGCACGGCGCAAGGCGGGCGGCCGCATGCCGAAACCG
AAGCCCTTGCCGCGGCGGGCGACGCGGCAAGGGGCGCCACCGCCTATGTCACGCTCGAACCCTGCGCCCATCACGGCCGG
ACGCCGCCCTGCGCCGATGCGCTGGTCGCGGCCGGCATCGCGCGCGTCGTCGTCGCCATGACCGACCCGGACGAGCGGAC
CAACGGCGCGGGCCTCTCCCGCCTGCGCGAGGCGGGACTCGAGGTGGTCGAGGGAATTGGCGGTGCCGAGGCCGCGGAAA
TCAATGCGGGGTTCTGCAAGCGCATCCGTGAGGGGCGGCCGCTGGTGACGCTGAAGCTCGCGACCTCGCTCGACGGGCAG
ATCGCGACGCGCACCGGCGCCAGCCAGTGGATCACCGGTGCGGCGGCCCGCCAGGCGGCGCACGCGTTGCGCGGGACGCA
TGACGCCGTGATGGTCGGCGTCGGCACCGTGCTGGCCGATGATCCGGAACTGACCTGCCGCCTCGAGGGCTTCCGCAGCA
CGCCGGTCATCCGCCTGATCGTCGATTCGCATTTGCGGATCCCGCTCGACGGGCGGCTGGTGCGCGGGGCCGCGGACCAC
CCCCTCTGGATCGTGCATCGCGACGGCGCCGACCCGGCCCGGCGCGCGGCGCTGCTCGATCTCGGCGCCCGGCTGTTCGA
GGTTCCCGCCGCCCCGGTGGGGATCGACCTTGCGGCGGCGCTCGCGGTGGTGGGCGCGGCGGGGCTGACCCGCGTGCTGG
CCGAGGGCGGCGGCACTCTTGCGGCGGCGCTGATCCGTGCCGATCTGGTGGACCGTCTGGAGTGGTTCACCGCCCCGGTC
GTGATCGGCGATGACGGGATCGGCGCGGTGGCCGGCTTCGGTGTGGAGGAGTTGGGCCGGGCGGCGCGTTTCACGCGCAT
CGACGCGTCGGTTTGCGGCGGCGACATCCGCACGCGCTATCGGAGGGATTGA

Upstream 100 bases:

>100_bases
ATGCGGTGGCCTATGTGCGCTTCGCCTCGGTCTATCGCGATTTCCGGGAAGCCAAGGATTTCAAGGCCTTCCTGGGTACG
ATGGACCCATCGAAATAGGC

Downstream 100 bases:

>100_bases
ACGATGTTCACCGGGATCATCACCGGGGTTGGCGATGTGCGCGACGTGCGCCCGGCGGACAGCGTCAGCGATACGCGTCT
CGTCATCGGCGTGCCGGCGG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDDLAHMRTALALARRGLGETAPNPTVGCVIVRGGRVVGRGRTAQGGRPHAETEALAAAGDAARGATAYVTLEPCAHHGR
TPPCADALVAAGIARVVVAMTDPDERTNGAGLSRLREAGLEVVEGIGGAEAAEINAGFCKRIREGRPLVTLKLATSLDGQ
IATRTGASQWITGAAARQAAHALRGTHDAVMVGVGTVLADDPELTCRLEGFRSTPVIRLIVDSHLRIPLDGRLVRGAADH
PLWIVHRDGADPARRAALLDLGARLFEVPAAPVGIDLAAALAVVGAAGLTRVLAEGGGTLAAALIRADLVDRLEWFTAPV
VIGDDGIGAVAGFGVEELGRAARFTRIDASVCGGDIRTRYRRD

Sequences:

>Translated_363_residues
MDDLAHMRTALALARRGLGETAPNPTVGCVIVRGGRVVGRGRTAQGGRPHAETEALAAAGDAARGATAYVTLEPCAHHGR
TPPCADALVAAGIARVVVAMTDPDERTNGAGLSRLREAGLEVVEGIGGAEAAEINAGFCKRIREGRPLVTLKLATSLDGQ
IATRTGASQWITGAAARQAAHALRGTHDAVMVGVGTVLADDPELTCRLEGFRSTPVIRLIVDSHLRIPLDGRLVRGAADH
PLWIVHRDGADPARRAALLDLGARLFEVPAAPVGIDLAAALAVVGAAGLTRVLAEGGGTLAAALIRADLVDRLEWFTAPV
VIGDDGIGAVAGFGVEELGRAARFTRIDASVCGGDIRTRYRRD
>Mature_363_residues
MDDLAHMRTALALARRGLGETAPNPTVGCVIVRGGRVVGRGRTAQGGRPHAETEALAAAGDAARGATAYVTLEPCAHHGR
TPPCADALVAAGIARVVVAMTDPDERTNGAGLSRLREAGLEVVEGIGGAEAAEINAGFCKRIREGRPLVTLKLATSLDGQ
IATRTGASQWITGAAARQAAHALRGTHDAVMVGVGTVLADDPELTCRLEGFRSTPVIRLIVDSHLRIPLDGRLVRGAADH
PLWIVHRDGADPARRAALLDLGARLFEVPAAPVGIDLAAALAVVGAAGLTRVLAEGGGTLAAALIRADLVDRLEWFTAPV
VIGDDGIGAVAGFGVEELGRAARFTRIDASVCGGDIRTRYRRD

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=369, Percent_Identity=41.4634146341463, Blast_Score=267, Evalue=9e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 37526; Mature: 37526

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLAHMRTALALARRGLGETAPNPTVGCVIVRGGRVVGRGRTAQGGRPHAETEALAAAG
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHCC
DAARGATAYVTLEPCAHHGRTPPCADALVAAGIARVVVAMTDPDERTNGAGLSRLREAGL
CCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHH
EVVEGIGGAEAAEINAGFCKRIREGRPLVTLKLATSLDGQIATRTGASQWITGAAARQAA
HHHHCCCCCCHHHCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHH
HALRGTHDAVMVGVGTVLADDPELTCRLEGFRSTPVIRLIVDSHLRIPLDGRLVRGAADH
HHHCCCCCEEEEECCCEEECCCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEECCCCC
PLWIVHRDGADPARRAALLDLGARLFEVPAAPVGIDLAAALAVVGAAGLTRVLAEGGGTL
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AAALIRADLVDRLEWFTAPVVIGDDGIGAVAGFGVEELGRAARFTRIDASVCGGDIRTRY
HHHHHHHHHHHHHHHHHCCEEECCCCCCHHHCCCHHHHHHHHHHEECCHHHCCCHHHHHC
RRD
CCC
>Mature Secondary Structure
MDDLAHMRTALALARRGLGETAPNPTVGCVIVRGGRVVGRGRTAQGGRPHAETEALAAAG
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCHHHHHHHCC
DAARGATAYVTLEPCAHHGRTPPCADALVAAGIARVVVAMTDPDERTNGAGLSRLREAGL
CCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHH
EVVEGIGGAEAAEINAGFCKRIREGRPLVTLKLATSLDGQIATRTGASQWITGAAARQAA
HHHHCCCCCCHHHCCHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHH
HALRGTHDAVMVGVGTVLADDPELTCRLEGFRSTPVIRLIVDSHLRIPLDGRLVRGAADH
HHHCCCCCEEEEECCCEEECCCCEEEEECCCCCCCEEEEEECCCEECCCCCEEEECCCCC
PLWIVHRDGADPARRAALLDLGARLFEVPAAPVGIDLAAALAVVGAAGLTRVLAEGGGTL
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
AAALIRADLVDRLEWFTAPVVIGDDGIGAVAGFGVEELGRAARFTRIDASVCGGDIRTRY
HHHHHHHHHHHHHHHHHCCEEECCCCCCHHHCCCHHHHHHHHHHEECCHHHCCCHHHHHC
RRD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]