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The map label for this gene is cutL [H]

Identifier: 148260961

GI number: 148260961

Start: 2157764

End: 2160076

Strand: Reverse

Name: cutL [H]

Synonym: Acry_1968

Alternate gene names: 148260961

Gene position: 2160076-2157764 (Counterclockwise)

Preceding gene: 148260964

Following gene: 148260960

Centisome position: 63.73

GC content: 69.65

Gene sequence:

>2313_bases
ATGGTGAAATTCGGTCTTGCCCAGCCGGTCAAGCGCGTCGAGGATTCGCGGCTGCTGCGCGGCGCTGGACAATATACCGA
CGACGTTCCGGGCGAGGGCGCGCTGCACCTGCACGTCCTGCGTTCGCCGCACGCCGCCGCGACGATCACCGGGATCGACG
CCGAGGCCGCCCGCGCGGTGCCGGGCGTCGTCGCCATCGTCACCGGCGCGGATCTCGCCGCCGAGGGCATCGCGCCGATT
CCCTGCATGGTGCCGATCAAGAACCAGGACGGCACGCCGCGCGCCCAGGCCGATCGCCCGGCCCTCGCCCAGGGCGCGGT
GCGCCATGTCGGCGAGCCGGTGGCCTATATCGTCGCCGAAACCGCGCAGGCCGCGCGCGATGCCGCCGAGCTGGTCGATG
TCCGCTACGACACGAAGCCCTCGATCACCGATCTGGCCAGCGCGATGTCCGACAGCGCGCCGCGCGTGCATGAGGACGCG
CCGGCCAACCGCGTCTTCGACTGGGCGGTGGGCGACGCCGCGAAGGTGGACGAGCTGTTCGCCGCCGCCGCGCATGTGAC
GAAGCTGCGCATCGTCAACAACCGCATCGTCGTCAACTCGCTGGAGCCCCGCGCCGCCCGCGCCGAGTTCGACGCGGCGT
CCGGCCGCTGGACGCTGACCACCAACACCCAGGGCGGCTGGCTGCTGAAGGACTGCCTCGCCGGCGCCGTGTTCAAGGTG
GAGCCGGCGAAGTTCCGGGTCATCACCCCGGATGTCGGCGGCGGCTTCGGCATGAAGCTGTTCGTCTATCCCGAGCATGT
CATGGTCTGCCACGCCGCCCGCAAGCTGGGCCGGCCGGTGAAATGGACCTCCGAGCGCAGCGAGGCGTTCCTCTCCGACA
CGCATGGGCGCGACCACATCACCATCGGCGAACTGGCGCTCGACGCCGATCACCGGATCACCGCCATGCGGGTGACGGAC
ACGGCGAACATGGGCGCCTATCTCTCGAATTTCGGCCCCTTCATCCCGACCCTCGCCGGCACCAAGGTGCTGGCCAGCGT
CTATGGCATGAAGGCGATCCATGCGCGGGTGTTCGGCGTGTTCACCAACACCGTGCCGGTCGACGCCTATCGCGGCGCCG
GCCGCCCGGAGAGCAACTATCTCGTCGAGCGGCTGATCGACGCCGCCGCCCGCGAACTCGGGATCGACCGCGCCGAGCTG
CGCCGCATCAACATGGTGCCGGCGAGCGCCATGCCCTTCACCACCGCGATGGCGCAGACCTACGATTCGGGCGATTTCCA
CAAGGTGCTCGACCATGCGCTCGACATGATCGACTGGAAGGGCTTCCCCGCCCGCCGCGCGAAGTCGGCTGCCGCCGGCA
AGCGGCGCGGCATCGGCATGGCCTATTACCTCGAGGCGACCGGCGGCGCGCCGGAGGAGCGCGCCGAGATCCGCTTCACC
AGGGATGGGCATGTCGATGTCTATGTCGGCACCCAGTCCACCGGCCAGGGCCATGAAACCGCCTATGTGCAGCTGGTGAA
CGACCGGCTCGGCATCGATCCTGACAAGATCCGCGTCCGCCAGGGCGATACCGACACGATTCCGCAGGGTGGCGGCACCG
GCGGCGCGCGCAGCCTTTATTCCGAGGGCCAGGCCATCGCGCTGACCACCGCGACCATTCTCGAAAAGGGCCGCAAGGCC
GCGGCCGATCATCTGGAGGCCGCGGAGGCCGACATCGTGTTCCAGGACGGCGCGTTCCGCATCGTCGGCACCGACCGGGC
GGTCGACGTCATCACCCTGGCGGCGGACCTGCACGGCGATCAGGGCAACGCGCTCGATACCGCCGAGATCGCCAAGATCG
AGAAGCACACCTTCCCGAACGGCTGCCACATCGCCGAGGTCGAGATCGATCCGGAAACCGGCGTCACCTCGGTGCTGCGC
TATCTGGTGTGCGACGATGTCGGCACCATCGTGAATCCGATGATCGTGCGCGGCCAGGTGCATGGCGGCGTCGCCCAGGG
GCTCGGGCAGGCGCTGCTGGAGAACACCGCCTACGACCCGGAGTCGGGCCAGCTCGTCGCCGGCAGTCTGATGGACTATG
CGCTGCCCCGCGCCGACGACCTGCCGGATATCGAGGTGGAGTTCGTCTCGGTGCCCTGCGCCTCGAACCCGCTCGGCGTG
AAGGGCGCGGGCGAGGCCGGCGCCGTCGGCTCGCCGCCGGCGCTGATCAACGCGGTGATCGACGCGCTTGCCGTCGACGG
TATCCGCGAGATCGACATGCCGGCGACGCCCGAGCGCGTCTGGCAGGCGATCTCGGCGCGGCAGGCCGCTTGA

Upstream 100 bases:

>100_bases
GCCTTGCCGGTCTATTGTATTTTCCCGACCGACCCATATCCTGAGCGCAGGGAAGGCGCGCTGCGGCCGCCGTCAGCAAC
TGGAAGATGAGGAATCGATC

Downstream 100 bases:

>100_bases
TCCACCTGGTCAAGCTCGCGGTCGGCGTGAAGGATCCCGGCCACCTGGCCGAGATCCAGCGCCGCCGCGCCGTGGCCGAT
CCGCCGCTGCGCCACCAGAC

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 770; Mature: 770

Protein sequence:

>770_residues
MVKFGLAQPVKRVEDSRLLRGAGQYTDDVPGEGALHLHVLRSPHAAATITGIDAEAARAVPGVVAIVTGADLAAEGIAPI
PCMVPIKNQDGTPRAQADRPALAQGAVRHVGEPVAYIVAETAQAARDAAELVDVRYDTKPSITDLASAMSDSAPRVHEDA
PANRVFDWAVGDAAKVDELFAAAAHVTKLRIVNNRIVVNSLEPRAARAEFDAASGRWTLTTNTQGGWLLKDCLAGAVFKV
EPAKFRVITPDVGGGFGMKLFVYPEHVMVCHAARKLGRPVKWTSERSEAFLSDTHGRDHITIGELALDADHRITAMRVTD
TANMGAYLSNFGPFIPTLAGTKVLASVYGMKAIHARVFGVFTNTVPVDAYRGAGRPESNYLVERLIDAAARELGIDRAEL
RRINMVPASAMPFTTAMAQTYDSGDFHKVLDHALDMIDWKGFPARRAKSAAAGKRRGIGMAYYLEATGGAPEERAEIRFT
RDGHVDVYVGTQSTGQGHETAYVQLVNDRLGIDPDKIRVRQGDTDTIPQGGGTGGARSLYSEGQAIALTTATILEKGRKA
AADHLEAAEADIVFQDGAFRIVGTDRAVDVITLAADLHGDQGNALDTAEIAKIEKHTFPNGCHIAEVEIDPETGVTSVLR
YLVCDDVGTIVNPMIVRGQVHGGVAQGLGQALLENTAYDPESGQLVAGSLMDYALPRADDLPDIEVEFVSVPCASNPLGV
KGAGEAGAVGSPPALINAVIDALAVDGIREIDMPATPERVWQAISARQAA

Sequences:

>Translated_770_residues
MVKFGLAQPVKRVEDSRLLRGAGQYTDDVPGEGALHLHVLRSPHAAATITGIDAEAARAVPGVVAIVTGADLAAEGIAPI
PCMVPIKNQDGTPRAQADRPALAQGAVRHVGEPVAYIVAETAQAARDAAELVDVRYDTKPSITDLASAMSDSAPRVHEDA
PANRVFDWAVGDAAKVDELFAAAAHVTKLRIVNNRIVVNSLEPRAARAEFDAASGRWTLTTNTQGGWLLKDCLAGAVFKV
EPAKFRVITPDVGGGFGMKLFVYPEHVMVCHAARKLGRPVKWTSERSEAFLSDTHGRDHITIGELALDADHRITAMRVTD
TANMGAYLSNFGPFIPTLAGTKVLASVYGMKAIHARVFGVFTNTVPVDAYRGAGRPESNYLVERLIDAAARELGIDRAEL
RRINMVPASAMPFTTAMAQTYDSGDFHKVLDHALDMIDWKGFPARRAKSAAAGKRRGIGMAYYLEATGGAPEERAEIRFT
RDGHVDVYVGTQSTGQGHETAYVQLVNDRLGIDPDKIRVRQGDTDTIPQGGGTGGARSLYSEGQAIALTTATILEKGRKA
AADHLEAAEADIVFQDGAFRIVGTDRAVDVITLAADLHGDQGNALDTAEIAKIEKHTFPNGCHIAEVEIDPETGVTSVLR
YLVCDDVGTIVNPMIVRGQVHGGVAQGLGQALLENTAYDPESGQLVAGSLMDYALPRADDLPDIEVEFVSVPCASNPLGV
KGAGEAGAVGSPPALINAVIDALAVDGIREIDMPATPERVWQAISARQAA
>Mature_770_residues
MVKFGLAQPVKRVEDSRLLRGAGQYTDDVPGEGALHLHVLRSPHAAATITGIDAEAARAVPGVVAIVTGADLAAEGIAPI
PCMVPIKNQDGTPRAQADRPALAQGAVRHVGEPVAYIVAETAQAARDAAELVDVRYDTKPSITDLASAMSDSAPRVHEDA
PANRVFDWAVGDAAKVDELFAAAAHVTKLRIVNNRIVVNSLEPRAARAEFDAASGRWTLTTNTQGGWLLKDCLAGAVFKV
EPAKFRVITPDVGGGFGMKLFVYPEHVMVCHAARKLGRPVKWTSERSEAFLSDTHGRDHITIGELALDADHRITAMRVTD
TANMGAYLSNFGPFIPTLAGTKVLASVYGMKAIHARVFGVFTNTVPVDAYRGAGRPESNYLVERLIDAAARELGIDRAEL
RRINMVPASAMPFTTAMAQTYDSGDFHKVLDHALDMIDWKGFPARRAKSAAAGKRRGIGMAYYLEATGGAPEERAEIRFT
RDGHVDVYVGTQSTGQGHETAYVQLVNDRLGIDPDKIRVRQGDTDTIPQGGGTGGARSLYSEGQAIALTTATILEKGRKA
AADHLEAAEADIVFQDGAFRIVGTDRAVDVITLAADLHGDQGNALDTAEIAKIEKHTFPNGCHIAEVEIDPETGVTSVLR
YLVCDDVGTIVNPMIVRGQVHGGVAQGLGQALLENTAYDPESGQLVAGSLMDYALPRADDLPDIEVEFVSVPCASNPLGV
KGAGEAGAVGSPPALINAVIDALAVDGIREIDMPATPERVWQAISARQAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=803, Percent_Identity=25.653798256538, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI71773480, Length=781, Percent_Identity=24.1997439180538, Blast_Score=130, Evalue=4e-30,
Organism=Escherichia coli, GI1789230, Length=766, Percent_Identity=28.9817232375979, Blast_Score=233, Evalue=3e-62,
Organism=Escherichia coli, GI1789246, Length=798, Percent_Identity=25.4385964912281, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1786478, Length=766, Percent_Identity=26.7624020887728, Blast_Score=134, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17539860, Length=761, Percent_Identity=22.8646517739816, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=559, Percent_Identity=24.5080500894454, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24647199, Length=806, Percent_Identity=24.4416873449132, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24647193, Length=772, Percent_Identity=23.4455958549223, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24647195, Length=793, Percent_Identity=24.7162673392182, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24647201, Length=764, Percent_Identity=24.4764397905759, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24647197, Length=775, Percent_Identity=24.7741935483871, Blast_Score=96, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 81739; Mature: 81739

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKFGLAQPVKRVEDSRLLRGAGQYTDDVPGEGALHLHVLRSPHAAATITGIDAEAARAV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHCC
PGVVAIVTGADLAAEGIAPIPCMVPIKNQDGTPRAQADRPALAQGAVRHVGEPVAYIVAE
CCEEEEEECCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
TAQAARDAAELVDVRYDTKPSITDLASAMSDSAPRVHEDAPANRVFDWAVGDAAKVDELF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
AAAAHVTKLRIVNNRIVVNSLEPRAARAEFDAASGRWTLTTNTQGGWLLKDCLAGAVFKV
HHHHHHEEEEEECCEEEEECCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCEEEE
EPAKFRVITPDVGGGFGMKLFVYPEHVMVCHAARKLGRPVKWTSERSEAFLSDTHGRDHI
CCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCCE
TIGELALDADHRITAMRVTDTANMGAYLSNFGPFIPTLAGTKVLASVYGMKAIHARVFGV
EEEHEEECCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
FTNTVPVDAYRGAGRPESNYLVERLIDAAARELGIDRAELRRINMVPASAMPFTTAMAQT
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHH
YDSGDFHKVLDHALDMIDWKGFPARRAKSAAAGKRRGIGMAYYLEATGGAPEERAEIRFT
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCEEEEEEECCCCCCCCCEEEEE
RDGHVDVYVGTQSTGQGHETAYVQLVNDRLGIDPDKIRVRQGDTDTIPQGGGTGGARSLY
ECCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHEEEECCCCCCCCCCCCCCCHHHHH
SEGQAIALTTATILEKGRKAAADHLEAAEADIVFQDGAFRIVGTDRAVDVITLAADLHGD
HCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCEEEEEEEEECCCC
QGNALDTAEIAKIEKHTFPNGCHIAEVEIDPETGVTSVLRYLVCDDVGTIVNPMIVRGQV
CCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
HGGVAQGLGQALLENTAYDPESGQLVAGSLMDYALPRADDLPDIEVEFVSVPCASNPLGV
CCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCC
KGAGEAGAVGSPPALINAVIDALAVDGIREIDMPATPERVWQAISARQAA
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKFGLAQPVKRVEDSRLLRGAGQYTDDVPGEGALHLHVLRSPHAAATITGIDAEAARAV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHCC
PGVVAIVTGADLAAEGIAPIPCMVPIKNQDGTPRAQADRPALAQGAVRHVGEPVAYIVAE
CCEEEEEECCCHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHH
TAQAARDAAELVDVRYDTKPSITDLASAMSDSAPRVHEDAPANRVFDWAVGDAAKVDELF
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
AAAAHVTKLRIVNNRIVVNSLEPRAARAEFDAASGRWTLTTNTQGGWLLKDCLAGAVFKV
HHHHHHEEEEEECCEEEEECCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCEEEE
EPAKFRVITPDVGGGFGMKLFVYPEHVMVCHAARKLGRPVKWTSERSEAFLSDTHGRDHI
CCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCCE
TIGELALDADHRITAMRVTDTANMGAYLSNFGPFIPTLAGTKVLASVYGMKAIHARVFGV
EEEHEEECCCCCEEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
FTNTVPVDAYRGAGRPESNYLVERLIDAAARELGIDRAELRRINMVPASAMPFTTAMAQT
EECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCHHHHHHHH
YDSGDFHKVLDHALDMIDWKGFPARRAKSAAAGKRRGIGMAYYLEATGGAPEERAEIRFT
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHCCCCEEEEEEECCCCCCCCCEEEEE
RDGHVDVYVGTQSTGQGHETAYVQLVNDRLGIDPDKIRVRQGDTDTIPQGGGTGGARSLY
ECCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHEEEECCCCCCCCCCCCCCCHHHHH
SEGQAIALTTATILEKGRKAAADHLEAAEADIVFQDGAFRIVGTDRAVDVITLAADLHGD
HCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCEEEEEEEEECCCC
QGNALDTAEIAKIEKHTFPNGCHIAEVEIDPETGVTSVLRYLVCDDVGTIVNPMIVRGQV
CCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEC
HGGVAQGLGQALLENTAYDPESGQLVAGSLMDYALPRADDLPDIEVEFVSVPCASNPLGV
CCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCC
KGAGEAGAVGSPPALINAVIDALAVDGIREIDMPATPERVWQAISARQAA
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]