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The map label for this gene is yfdH [C]

Identifier: 148260897

GI number: 148260897

Start: 2102514

End: 2103608

Strand: Reverse

Name: yfdH [C]

Synonym: Acry_1904

Alternate gene names: 148260897

Gene position: 2103608-2102514 (Counterclockwise)

Preceding gene: 148260898

Following gene: 148260896

Centisome position: 62.07

GC content: 72.05

Gene sequence:

>1095_bases
GTGACGGCCTGCCGCAGCCCGGTCCTCAGCGTCGTCGTTCCCTGCTATCGCGAGCAGCCGAACGTCGCCCCCATGGTCGC
CGCCCTCGATGCCGCCCTCGCCGGCATCGACTGGGAGGTGATCTTCGTCGACGACGACAGCCCCGACGGCACGGCCGACG
CAGCCCGCGCCCTGGCGCGGACCGACACCCGCGTCCGCTGCCTCCGCCGCGTCGGCCGCCGCGGCCTGTCCTCGGCCGTC
ATCGAGGGGGCGCTGTCCAGTTCCGCCCCCTTCGTCGCGGTGATCGACGGCGACCTCCAGCACGACGAGACCATCCTCCC
CGCGATGCTCGACGCCGTGCGCGCGGGGGCGGACATCGCGGTGGGCAGCCGCCACGTCGGCGGCGGCGACGCCGCCGGCC
TCGCCTCGCCGCTGCGCCAGCGCCTTTCCGCCGCCGGCATCGGCCTCGCCCGGAAACTCGCCGGTGTTGCGATCTCCGAC
CCGATGAGCGGCTTCTTCCTCCTCCGCCAGTCGCTGTTCGAGGACCTGGCGCACCGGCTGAACGGGCAGGGCTTCAAGAT
CCTGCTCGACCTGCTGCTCTCCGCGCCGGCCCCGCTGAAGGTCGCCGAACTCCCCTACCGCTTCCGCCCCCGCGCCGCCG
GCGAAAGCAAGCTCGACATCCTGGTGATGGTCCAGTTCGCCGGCCAGTTCGTCGACCGCGCGCTCGGCGGCATGGTGCCG
CTGCGCTTCATCGCCTTCGCCCTGGTCGGCCTGTTCGGCATTTTCGTGAACCTCGCGGCAATGCAGGCGAGCCGCGCCGC
CGGGCTCGGTTTCGGCCCGGCGCAGACGCTCGGCACCATCGTCGCCATGGTCGCCAATTTCGAGCTGAACAACCGCCTGA
CCTACCGCACGATGAAGCTGCGCGGCGTGCGCTACTGGCAGGGTCTCGTGCTGTTCATGCTGGTCTGCGGCCTCGGCGCC
ATCGCCAATATCGGCATCGCCGGCGCGCTCTATCATCGGGGCGACGCCAACGGCCTCGCCGCCAGCGCCGCCGGCTCGGC
GATCGGCGTGGTCTGGAACTACGCGGTCTCCGCCACCCTGGTCTGGCGCGTGTGA

Upstream 100 bases:

>100_bases
GACGGGCTGGTGACGCACCTCGCCATCGAGCAACCGGGCGGCTTCGAGGTCAGCCGGGCCGAGGCGGTGCTGGAGGCGCT
CGGCGGCTGAGCCTGCCCGC

Downstream 100 bases:

>100_bases
TGAGCGCGCAAAAGTCGTGCGTGCGATGAGCGCGCAAAAGCCGTGCGTGCGATGAGCGCGCAGAACCGATGCGTGCGATG
AGCGCGCCGGACCGGTCCGG

Product: dolichyl-phosphate beta-D-mannosyltransferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: Dolichol-Phosphate Mannosyltransferase; Glycosyl Transferase Family Protein; Dolichyl-Phosphate-Mannose Synthase; Dolichol Monophosphate Mannose Synthase; GtrA-Like Protein; Glycosyltransferase; Glycosyl Transferase Family 2 Protein; GtrA Family Protein; Glycosyl Transferase; Dolichol-Phosphate-Mannosyltransferase Related Protein; Glycosyltransferase Protein; UndP-Glycosyltransferase; Cell Wall Biogenesis Glycosyltransferase; Dolichyl Phosphoryl Mannose Synthase; GAF Sensor Protein; Glycosyltransferase Group 2 Family Protein; Monosaccharide Translocase; Cell Wall Biosynthesis Glycosyltransferase; Glycosyl Transferase Group 2 Family Protein

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTACRSPVLSVVVPCYREQPNVAPMVAALDAALAGIDWEVIFVDDDSPDGTADAARALARTDTRVRCLRRVGRRGLSSAV
IEGALSSSAPFVAVIDGDLQHDETILPAMLDAVRAGADIAVGSRHVGGGDAAGLASPLRQRLSAAGIGLARKLAGVAISD
PMSGFFLLRQSLFEDLAHRLNGQGFKILLDLLLSAPAPLKVAELPYRFRPRAAGESKLDILVMVQFAGQFVDRALGGMVP
LRFIAFALVGLFGIFVNLAAMQASRAAGLGFGPAQTLGTIVAMVANFELNNRLTYRTMKLRGVRYWQGLVLFMLVCGLGA
IANIGIAGALYHRGDANGLAASAAGSAIGVVWNYAVSATLVWRV

Sequences:

>Translated_364_residues
MTACRSPVLSVVVPCYREQPNVAPMVAALDAALAGIDWEVIFVDDDSPDGTADAARALARTDTRVRCLRRVGRRGLSSAV
IEGALSSSAPFVAVIDGDLQHDETILPAMLDAVRAGADIAVGSRHVGGGDAAGLASPLRQRLSAAGIGLARKLAGVAISD
PMSGFFLLRQSLFEDLAHRLNGQGFKILLDLLLSAPAPLKVAELPYRFRPRAAGESKLDILVMVQFAGQFVDRALGGMVP
LRFIAFALVGLFGIFVNLAAMQASRAAGLGFGPAQTLGTIVAMVANFELNNRLTYRTMKLRGVRYWQGLVLFMLVCGLGA
IANIGIAGALYHRGDANGLAASAAGSAIGVVWNYAVSATLVWRV
>Mature_363_residues
TACRSPVLSVVVPCYREQPNVAPMVAALDAALAGIDWEVIFVDDDSPDGTADAARALARTDTRVRCLRRVGRRGLSSAVI
EGALSSSAPFVAVIDGDLQHDETILPAMLDAVRAGADIAVGSRHVGGGDAAGLASPLRQRLSAAGIGLARKLAGVAISDP
MSGFFLLRQSLFEDLAHRLNGQGFKILLDLLLSAPAPLKVAELPYRFRPRAAGESKLDILVMVQFAGQFVDRALGGMVPL
RFIAFALVGLFGIFVNLAAMQASRAAGLGFGPAQTLGTIVAMVANFELNNRLTYRTMKLRGVRYWQGLVLFMLVCGLGAI
ANIGIAGALYHRGDANGLAASAAGSAIGVVWNYAVSATLVWRV

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4503363, Length=221, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71999402, Length=226, Percent_Identity=28.7610619469027, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325441, Length=263, Percent_Identity=33.4600760456274, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24585265, Length=224, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.83

Molecular weight: Translated: 38254; Mature: 38123

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTACRSPVLSVVVPCYREQPNVAPMVAALDAALAGIDWEVIFVDDDSPDGTADAARALAR
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
TDTRVRCLRRVGRRGLSSAVIEGALSSSAPFVAVIDGDLQHDETILPAMLDAVRAGADIA
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEE
VGSRHVGGGDAAGLASPLRQRLSAAGIGLARKLAGVAISDPMSGFFLLRQSLFEDLAHRL
ECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHH
NGQGFKILLDLLLSAPAPLKVAELPYRFRPRAAGESKLDILVMVQFAGQFVDRALGGMVP
CCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHCCHHH
LRFIAFALVGLFGIFVNLAAMQASRAAGLGFGPAQTLGTIVAMVANFELNNRLTYRTMKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHH
RGVRYWQGLVLFMLVCGLGAIANIGIAGALYHRGDANGLAASAAGSAIGVVWNYAVSATL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCHHHCCCHHHHHHHHHHHEEE
VWRV
EEEC
>Mature Secondary Structure 
TACRSPVLSVVVPCYREQPNVAPMVAALDAALAGIDWEVIFVDDDSPDGTADAARALAR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
TDTRVRCLRRVGRRGLSSAVIEGALSSSAPFVAVIDGDLQHDETILPAMLDAVRAGADIA
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEE
VGSRHVGGGDAAGLASPLRQRLSAAGIGLARKLAGVAISDPMSGFFLLRQSLFEDLAHRL
ECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHH
NGQGFKILLDLLLSAPAPLKVAELPYRFRPRAAGESKLDILVMVQFAGQFVDRALGGMVP
CCCHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHCCHHH
LRFIAFALVGLFGIFVNLAAMQASRAAGLGFGPAQTLGTIVAMVANFELNNRLTYRTMKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHH
RGVRYWQGLVLFMLVCGLGAIANIGIAGALYHRGDANGLAASAAGSAIGVVWNYAVSATL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCHHHCCCHHHHHHHHHHHEEE
VWRV
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA