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The map label for this gene is pcaI [H]

Identifier: 148260840

GI number: 148260840

Start: 2036434

End: 2037120

Strand: Reverse

Name: pcaI [H]

Synonym: Acry_1846

Alternate gene names: 148260840

Gene position: 2037120-2036434 (Counterclockwise)

Preceding gene: 148260841

Following gene: 148260839

Centisome position: 60.11

GC content: 71.18

Gene sequence:

>687_bases
ATGATCGACAAGTTCGTGGCCTCGGTCGAGGCGGCGCTGGAGGGGATCGGCGATGGCGCCGCGATCATGGTGGGCGGGTT
CGGCGCGGTGGGGCAGCCGAACGCGCTGGTCGACGCGCTGGCGGCGCGCAACCTGCGGGGGTTGACGCTGATCGCCAACA
ACGCGGGCGGGGATTTCGGCGGGATGCCGAAGCTGATCGAGCGCGGGGCGATTGCCAGGGTGATCTGCTCCTATCCGCGG
GCGAGCCGGCGGACGGCGTTCGACGAGCTGTACGAGGCGGGGAAGATCGAGCTGGAACTGGTGCCGCAGGGCACGCTGGC
GGAGCGGATCCGCGCCGCGAATGCCGGGATTCCGGCCTTCTTCACGCCGACCTCGGCGGGGACGGAACTCGCGGCGGGGA
AGGAGACGCGGCGGATCAACGGGCGGGACTGCGTTCTGGAATACGCGATCGAGGCGGATTTCGCGCTGATCGAGGCCTGG
GCGGCGGACCGGTGGGGGAACCTGACGTTCCGGCGGGCGGGGCGCAACTTCAACCAGATCATGGCGGGGGCGGCGAAGGT
GACGGTGGCGAGCGTGCACCGGCGGGTCGAGCTCGGCGCGCTGGATCCGGACCGGATCGTGACGCCCGGCGTGTTCGTCG
ACCGGGTGGTGCTGGTGCCGGAGCCGATGGAAGGGGAGGCGGCGTGA

Upstream 100 bases:

>100_bases
CTGCGGGCGCTGGAAGCGCGGGGCGGCAGGCTGGCGATCGCGACGATGTGCATCGGTGTCGGCCAGGGCATCGCAGTGCT
GATCGAGCGGGTGTGAGGCG

Downstream 100 bases:

>100_bases
TGGAGGGGACGGTGATGCGGCGGGGCTGGTCGCGCGCGGAGATGGCCGCGCGGGTGGCGGCGGATATTCCCGAGGGCTGG
GTGGTCAATCTCGGCATCGG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIDKFVASVEAALEGIGDGAAIMVGGFGAVGQPNALVDALAARNLRGLTLIANNAGGDFGGMPKLIERGAIARVICSYPR
ASRRTAFDELYEAGKIELELVPQGTLAERIRAANAGIPAFFTPTSAGTELAAGKETRRINGRDCVLEYAIEADFALIEAW
AADRWGNLTFRRAGRNFNQIMAGAAKVTVASVHRRVELGALDPDRIVTPGVFVDRVVLVPEPMEGEAA

Sequences:

>Translated_228_residues
MIDKFVASVEAALEGIGDGAAIMVGGFGAVGQPNALVDALAARNLRGLTLIANNAGGDFGGMPKLIERGAIARVICSYPR
ASRRTAFDELYEAGKIELELVPQGTLAERIRAANAGIPAFFTPTSAGTELAAGKETRRINGRDCVLEYAIEADFALIEAW
AADRWGNLTFRRAGRNFNQIMAGAAKVTVASVHRRVELGALDPDRIVTPGVFVDRVVLVPEPMEGEAA
>Mature_228_residues
MIDKFVASVEAALEGIGDGAAIMVGGFGAVGQPNALVDALAARNLRGLTLIANNAGGDFGGMPKLIERGAIARVICSYPR
ASRRTAFDELYEAGKIELELVPQGTLAERIRAANAGIPAFFTPTSAGTELAAGKETRRINGRDCVLEYAIEADFALIEAW
AADRWGNLTFRRAGRNFNQIMAGAAKVTVASVHRRVELGALDPDRIVTPGVFVDRVVLVPEPMEGEAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=232, Percent_Identity=42.6724137931034, Blast_Score=184, Evalue=5e-47,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=42.6724137931034, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=42.3076923076923, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1787985, Length=246, Percent_Identity=25.609756097561, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17531517, Length=238, Percent_Identity=42.0168067226891, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=40.2597402597403, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=40.2597402597403, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24123; Mature: 24123

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKFVASVEAALEGIGDGAAIMVGGFGAVGQPNALVDALAARNLRGLTLIANNAGGDFG
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCC
GMPKLIERGAIARVICSYPRASRRTAFDELYEAGKIELELVPQGTLAERIRAANAGIPAF
CCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEE
FTPTSAGTELAAGKETRRINGRDCVLEYAIEADFALIEAWAADRWGNLTFRRAGRNFNQI
ECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCHHHH
MAGAAKVTVASVHRRVELGALDPDRIVTPGVFVDRVVLVPEPMEGEAA
HHHHHHHHHHHHHHHHEECCCCCCCEECCCHHHCEEEECCCCCCCCCC
>Mature Secondary Structure
MIDKFVASVEAALEGIGDGAAIMVGGFGAVGQPNALVDALAARNLRGLTLIANNAGGDFG
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCC
GMPKLIERGAIARVICSYPRASRRTAFDELYEAGKIELELVPQGTLAERIRAANAGIPAF
CCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEE
FTPTSAGTELAAGKETRRINGRDCVLEYAIEADFALIEAWAADRWGNLTFRRAGRNFNQI
ECCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCHHHH
MAGAAKVTVASVHRRVELGALDPDRIVTPGVFVDRVVLVPEPMEGEAA
HHHHHHHHHHHHHHHHEECCCCCCCEECCCHHHCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]