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The map label for this gene is hfq [H]

Identifier: 148260757

GI number: 148260757

Start: 1944851

End: 1945378

Strand: Reverse

Name: hfq [H]

Synonym: Acry_1762

Alternate gene names: 148260757

Gene position: 1945378-1944851 (Counterclockwise)

Preceding gene: 148260758

Following gene: 148260756

Centisome position: 57.4

GC content: 65.91

Gene sequence:

>528_bases
ATGCACCCGCCACAAGCGTTTTTTTATCCCATGCCGGGCGCTTCCGATTGGTTTCGGCGCCCCGGCGAGCTATATCTCCG
CCTGCGGCATCCGTTTGCGGGCTCTCCGAACGGGCGGGGCCGAACATGCGGCAGCGGGTTCCGGCCCGATGCCATGACCC
GATGCACCCACGCCATGGCAACCGCCATGCCCGGCAAGAAAAAAAGGACTCCAGACGTGGCCAACGAAAAATCGCAGAAC
GTGCAGGATGTCTTCCTCAATCACGTTCGCAAGAGCAAGACCCCGGTCACCGTGTTCCTGGTGAACGGCGTGAAGCTCCA
GGGTGTGATCACCTGGTTCGACAATTTCTCCGTCCTCCTCCGCCGCGACGGGCACACCCAGCTCGTCTACAAGCACGCGA
TCTCGACCGTGATGCCCGGCGCGCCGATCCAGCTCTTCGACGCGACCAAGGCCGAGGGCGCCGCGCCGGCGGGCGGCTCC
ACGCTCAGCCTCGGCCGCGCCGGCGACCCCGACCGCGACGCCGGGTAG

Upstream 100 bases:

>100_bases
CCCAAGCCCTGTTCTGGACCGCGCCGGCCGCCATGCGGCGCGCCAGCGCCTGATCTCCGCCGGCCCACCGGCCGCGCCCT
GTGATGGTGGCGGGTGTGTG

Downstream 100 bases:

>100_bases
GCCGGGTTGAGCATACCCACCCAGGCCGCGCCCACCCGCGCCGCCGTCCTGCTGCCTTGGGAACATGGCGGGCGCAACGG
CCCGCGCGAGGCCGAGGCCC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MHPPQAFFYPMPGASDWFRRPGELYLRLRHPFAGSPNGRGRTCGSGFRPDAMTRCTHAMATAMPGKKKRTPDVANEKSQN
VQDVFLNHVRKSKTPVTVFLVNGVKLQGVITWFDNFSVLLRRDGHTQLVYKHAISTVMPGAPIQLFDATKAEGAAPAGGS
TLSLGRAGDPDRDAG

Sequences:

>Translated_175_residues
MHPPQAFFYPMPGASDWFRRPGELYLRLRHPFAGSPNGRGRTCGSGFRPDAMTRCTHAMATAMPGKKKRTPDVANEKSQN
VQDVFLNHVRKSKTPVTVFLVNGVKLQGVITWFDNFSVLLRRDGHTQLVYKHAISTVMPGAPIQLFDATKAEGAAPAGGS
TLSLGRAGDPDRDAG
>Mature_175_residues
MHPPQAFFYPMPGASDWFRRPGELYLRLRHPFAGSPNGRGRTCGSGFRPDAMTRCTHAMATAMPGKKKRTPDVANEKSQN
VQDVFLNHVRKSKTPVTVFLVNGVKLQGVITWFDNFSVLLRRDGHTQLVYKHAISTVMPGAPIQLFDATKAEGAAPAGGS
TLSLGRAGDPDRDAG

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 19076; Mature: 19076

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPPQAFFYPMPGASDWFRRPGELYLRLRHPFAGSPNGRGRTCGSGFRPDAMTRCTHAMA
CCCCCCEEEECCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
TAMPGKKKRTPDVANEKSQNVQDVFLNHVRKSKTPVTVFLVNGVKLQGVITWFDNFSVLL
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEEECCEEEEE
RRDGHTQLVYKHAISTVMPGAPIQLFDATKAEGAAPAGGSTLSLGRAGDPDRDAG
ECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MHPPQAFFYPMPGASDWFRRPGELYLRLRHPFAGSPNGRGRTCGSGFRPDAMTRCTHAMA
CCCCCCEEEECCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
TAMPGKKKRTPDVANEKSQNVQDVFLNHVRKSKTPVTVFLVNGVKLQGVITWFDNFSVLL
HCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEEEEEEECCEEEEE
RRDGHTQLVYKHAISTVMPGAPIQLFDATKAEGAAPAGGSTLSLGRAGDPDRDAG
ECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA