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The map label for this gene is hflX [H]

Identifier: 148260756

GI number: 148260756

Start: 1943537

End: 1944844

Strand: Reverse

Name: hflX [H]

Synonym: Acry_1761

Alternate gene names: 148260756

Gene position: 1944844-1943537 (Counterclockwise)

Preceding gene: 148260757

Following gene: 148260755

Centisome position: 57.38

GC content: 71.87

Gene sequence:

>1308_bases
TTGAGCATACCCACCCAGGCCGCGCCCACCCGCGCCGCCGTCCTGCTGCCTTGGGAACATGGCGGGCGCAACGGCCCGCG
CGAGGCCGAGGCCCGCCTCGCCGAGGCGATCGGACTCACCGCCTCGATCGGCCTCGTCATCGCCCATGACGAAATCGTGC
AGATCCGCGCGCACCGCCCCGCCACCCTGTTCGGCGAGGGCCAGGTGCGGCGGATCGGCGAGTCCATCGCCGAGGCCGAG
ATCGGCGTCGCGGTGGTCGATTCCACGCTCAGCCCGGTGCAACAGCGCAATCTCGAACGCGCCTGGAAGTGCAAGGTCAT
CGACCGCACCGGCCTGATCCTCGACATTTTCGGCGAGCGCGCCCGCACCGCCGAGGGCGTGTTGCAGGTCGAACTCGCGC
ATCTCGCCTACCAGCGTTCCCGTCTCGTCCGCTCCTGGACCCATCTGGAGCGCCAGCGCGGCGGCTTCGGCTTCCTCGGT
GGCCCCGGCGAAACCCAGATCGAGGCGGACCGCCGCCTGATCACCGACCGCATCGCCCGCCTCCGCCGCGAGCTCGACGA
GGTCCGCCGCACCCGCGCCCTGCACCGCGCCGCGCGCAACCGCGTGCCCTATCCGGTCGTCGCCCTGGTCGGCTACACCA
ATGCCGGCAAATCCACGCTGTTCAACGCGCTCACCGGGGCCACCGTCCACGCGCAGGACCAGCTTTTCGCCACCCTCGAC
CCGACGATGCGCCTCATCGTCCTGCCCTCCGGCCGCCAGGCCATCCTGTCGGACACGGTGGGCTTCATCTCCGACCTGCC
GACCGAACTCGTCGCCGCCTTCCGCGCCACCCTCGAAGAGGTCGCCGCCGCCGACATCATCCTCCATGTCCGCGACTGCG
CCCACCCCGACAGCGCCGCCCAGCGCGCCGACGTCGTCTCCGTGCTCGACGGCATGGCCCGCTCGGGCATGATCGACGAG
GGCTGGTCGTCCCGCTGCATCGAGGTGATGAACAAGATCGACCTGCTCGATCCCGCCGCGCGCGACCTGCCGGGCGCTTC
CGCCATCGCCGTCTCGGCGCTGTCCGGCGAGAATCTCGACACGCTGCGCGCCACGATCGATGCCCGGCTCGCCGGCGCCA
TGCAGGTCGCGACCTACTGGCTCGCGCCGGCCGACGGCGCCGGCCTCGCCTGGCTCTACCGCCATGGCGAGGTGATCTCC
CGCGCGGATGGCGAGGACGCCATCGCCATCGAGGTCCGGCTCCGCCCCGAGGACCGCGCCCGTTTCGAGCGCGATCACGA
AGCCGCGCTGCACGCCCCGGTCCCCTGA

Upstream 100 bases:

>100_bases
CTTCGACGCGACCAAGGCCGAGGGCGCCGCGCCGGCGGGCGGCTCCACGCTCAGCCTCGGCCGCGCCGGCGACCCCGACC
GCGACGCCGGGTAGGCCGGG

Downstream 100 bases:

>100_bases
CCCACCGCCACGGATTCCAGCCCATGATGCCTGACAGAACCGACCTTTCCGCCATCGCGGCGCTGCTGCGCGACGTCGCG
CGCACGATCGTGATGCCCCG

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSIPTQAAPTRAAVLLPWEHGGRNGPREAEARLAEAIGLTASIGLVIAHDEIVQIRAHRPATLFGEGQVRRIGESIAEAE
IGVAVVDSTLSPVQQRNLERAWKCKVIDRTGLILDIFGERARTAEGVLQVELAHLAYQRSRLVRSWTHLERQRGGFGFLG
GPGETQIEADRRLITDRIARLRRELDEVRRTRALHRAARNRVPYPVVALVGYTNAGKSTLFNALTGATVHAQDQLFATLD
PTMRLIVLPSGRQAILSDTVGFISDLPTELVAAFRATLEEVAAADIILHVRDCAHPDSAAQRADVVSVLDGMARSGMIDE
GWSSRCIEVMNKIDLLDPAARDLPGASAIAVSALSGENLDTLRATIDARLAGAMQVATYWLAPADGAGLAWLYRHGEVIS
RADGEDAIAIEVRLRPEDRARFERDHEAALHAPVP

Sequences:

>Translated_435_residues
MSIPTQAAPTRAAVLLPWEHGGRNGPREAEARLAEAIGLTASIGLVIAHDEIVQIRAHRPATLFGEGQVRRIGESIAEAE
IGVAVVDSTLSPVQQRNLERAWKCKVIDRTGLILDIFGERARTAEGVLQVELAHLAYQRSRLVRSWTHLERQRGGFGFLG
GPGETQIEADRRLITDRIARLRRELDEVRRTRALHRAARNRVPYPVVALVGYTNAGKSTLFNALTGATVHAQDQLFATLD
PTMRLIVLPSGRQAILSDTVGFISDLPTELVAAFRATLEEVAAADIILHVRDCAHPDSAAQRADVVSVLDGMARSGMIDE
GWSSRCIEVMNKIDLLDPAARDLPGASAIAVSALSGENLDTLRATIDARLAGAMQVATYWLAPADGAGLAWLYRHGEVIS
RADGEDAIAIEVRLRPEDRARFERDHEAALHAPVP
>Mature_434_residues
SIPTQAAPTRAAVLLPWEHGGRNGPREAEARLAEAIGLTASIGLVIAHDEIVQIRAHRPATLFGEGQVRRIGESIAEAEI
GVAVVDSTLSPVQQRNLERAWKCKVIDRTGLILDIFGERARTAEGVLQVELAHLAYQRSRLVRSWTHLERQRGGFGFLGG
PGETQIEADRRLITDRIARLRRELDEVRRTRALHRAARNRVPYPVVALVGYTNAGKSTLFNALTGATVHAQDQLFATLDP
TMRLIVLPSGRQAILSDTVGFISDLPTELVAAFRATLEEVAAADIILHVRDCAHPDSAAQRADVVSVLDGMARSGMIDEG
WSSRCIEVMNKIDLLDPAARDLPGASAIAVSALSGENLDTLRATIDARLAGAMQVATYWLAPADGAGLAWLYRHGEVISR
ADGEDAIAIEVRLRPEDRARFERDHEAALHAPVP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=284, Percent_Identity=39.4366197183099, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI310133116, Length=282, Percent_Identity=39.3617021276596, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI310124269, Length=263, Percent_Identity=40.3041825095057, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI310124267, Length=263, Percent_Identity=40.3041825095057, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI310124171, Length=263, Percent_Identity=40.3041825095057, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI310124169, Length=263, Percent_Identity=40.3041825095057, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1790615, Length=365, Percent_Identity=44.1095890410959, Blast_Score=269, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17561038, Length=408, Percent_Identity=32.3529411764706, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24650079, Length=417, Percent_Identity=33.8129496402878, Blast_Score=169, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47293; Mature: 47162

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPTQAAPTRAAVLLPWEHGGRNGPREAEARLAEAIGLTASIGLVIAHDEIVQIRAHRP
CCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCCC
ATLFGEGQVRRIGESIAEAEIGVAVVDSTLSPVQQRNLERAWKCKVIDRTGLILDIFGER
EEEECCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCHHHEEEEECCCCCEEEECCCH
ARTAEGVLQVELAHLAYQRSRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLITDRIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHH
LRRELDEVRRTRALHRAARNRVPYPVVALVGYTNAGKSTLFNALTGATVHAQDQLFATLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCEEEEEC
PTMRLIVLPSGRQAILSDTVGFISDLPTELVAAFRATLEEVAAADIILHVRDCAHPDSAA
CCEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHH
QRADVVSVLDGMARSGMIDEGWSSRCIEVMNKIDLLDPAARDLPGASAIAVSALSGENLD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCHH
TLRATIDARLAGAMQVATYWLAPADGAGLAWLYRHGEVISRADGEDAIAIEVRLRPEDRA
HHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCHHHCCCCCCEEEEEEEECCCHHH
RFERDHEAALHAPVP
HHCCCCCCCCCCCCC
>Mature Secondary Structure 
SIPTQAAPTRAAVLLPWEHGGRNGPREAEARLAEAIGLTASIGLVIAHDEIVQIRAHRP
CCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHEEEEEECCCEEEEECCCC
ATLFGEGQVRRIGESIAEAEIGVAVVDSTLSPVQQRNLERAWKCKVIDRTGLILDIFGER
EEEECCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCHHHEEEEECCCCCEEEECCCH
ARTAEGVLQVELAHLAYQRSRLVRSWTHLERQRGGFGFLGGPGETQIEADRRLITDRIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHH
LRRELDEVRRTRALHRAARNRVPYPVVALVGYTNAGKSTLFNALTGATVHAQDQLFATLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEECCCEEEEEC
PTMRLIVLPSGRQAILSDTVGFISDLPTELVAAFRATLEEVAAADIILHVRDCAHPDSAA
CCEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHH
QRADVVSVLDGMARSGMIDEGWSSRCIEVMNKIDLLDPAARDLPGASAIAVSALSGENLD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCEEEEECCCCCHH
TLRATIDARLAGAMQVATYWLAPADGAGLAWLYRHGEVISRADGEDAIAIEVRLRPEDRA
HHHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCHHHCCCCCCEEEEEEEECCCHHH
RFERDHEAALHAPVP
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]