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The map label for this gene is suhB [H]

Identifier: 148260755

GI number: 148260755

Start: 1942680

End: 1943513

Strand: Reverse

Name: suhB [H]

Synonym: Acry_1760

Alternate gene names: 148260755

Gene position: 1943513-1942680 (Counterclockwise)

Preceding gene: 148260756

Following gene: 148260753

Centisome position: 57.34

GC content: 72.54

Gene sequence:

>834_bases
ATGATGCCTGACAGAACCGACCTTTCCGCCATCGCGGCGCTGCTGCGCGACGTCGCGCGCACGATCGTGATGCCCCGCTT
CGGCCATATCGGCCCGGCCGACCTGCGCACCAAGTCCGGCCCGCTCGACCCCGTCACGGTGGCCGACGAGGCGGCCGAGC
GCGCCCTCACCGAAGGCCTGCGCGCCCTGTTCCCCGATGTCGCGGTGATCGGCGAGGAATCCGTCGCCGCCGATCCCGCC
CTGCTCGGCGCGGTCGCCGGCCCCGGTCCCGTCTTCGTCATCGACCCGATCGATGGCACCCAGAACTACGCCGCCGGCCT
GCCGCTGTTCGGCCTGATGATCGCCCTGGTCGAGGACAATCGAACCATCGCCGGGCTGATCCACGACCCGCTGCGCGACG
ACACCATGCTCGCCACAAGCGGCGGCGGCGCCTTCCTGCTCCGCGGCGCGTCCGATTCAGCCGAATGGCTGCCCCTGCGC
GTCGCCGCCCCGGCGCCGCTTGCGCAGATGATCGCCTCGGTCTCCTGGCAATACATGGCGCGGGCCGAAAAATCCCGCGT
GCTCGGCAGTCTCGCCGCCCTCGGGCAGACGCCCAACCTGCGCTGCGCCGCCGCCACCTACCGCGCCATGGCCTCCGGCC
ATATGCACGCCTCGGTCTCCCGCCGCACTTTGCCGTGGGACCACGCCGCCGGCACGCTGATCGTCGAGGAAGCCGGCGGC
CATGTCCGCCGGCCGGATGGCGAGGCCTGGCGCCCGGCCGACATCGATGGCGGCCTCATCGCCGCCACCGACCGCGACAC
CTGGCACCGCCTGCGCGACGCGCTCTACGGCTAG

Upstream 100 bases:

>100_bases
AGGTCCGGCTCCGCCCCGAGGACCGCGCCCGTTTCGAGCGCGATCACGAAGCCGCGCTGCACGCCCCGGTCCCCTGACCC
ACCGCCACGGATTCCAGCCC

Downstream 100 bases:

>100_bases
AGCACGTTCCGATCCGAACGGATCGGAGGATGCCCTAGCCCTCCCGCTTCACCGCCTGCCAGAGCGCTTCCATCTCGGCG
AGCCCGGCCGCCTCCGGCGT

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MMPDRTDLSAIAALLRDVARTIVMPRFGHIGPADLRTKSGPLDPVTVADEAAERALTEGLRALFPDVAVIGEESVAADPA
LLGAVAGPGPVFVIDPIDGTQNYAAGLPLFGLMIALVEDNRTIAGLIHDPLRDDTMLATSGGGAFLLRGASDSAEWLPLR
VAAPAPLAQMIASVSWQYMARAEKSRVLGSLAALGQTPNLRCAAATYRAMASGHMHASVSRRTLPWDHAAGTLIVEEAGG
HVRRPDGEAWRPADIDGGLIAATDRDTWHRLRDALYG

Sequences:

>Translated_277_residues
MMPDRTDLSAIAALLRDVARTIVMPRFGHIGPADLRTKSGPLDPVTVADEAAERALTEGLRALFPDVAVIGEESVAADPA
LLGAVAGPGPVFVIDPIDGTQNYAAGLPLFGLMIALVEDNRTIAGLIHDPLRDDTMLATSGGGAFLLRGASDSAEWLPLR
VAAPAPLAQMIASVSWQYMARAEKSRVLGSLAALGQTPNLRCAAATYRAMASGHMHASVSRRTLPWDHAAGTLIVEEAGG
HVRRPDGEAWRPADIDGGLIAATDRDTWHRLRDALYG
>Mature_277_residues
MMPDRTDLSAIAALLRDVARTIVMPRFGHIGPADLRTKSGPLDPVTVADEAAERALTEGLRALFPDVAVIGEESVAADPA
LLGAVAGPGPVFVIDPIDGTQNYAAGLPLFGLMIALVEDNRTIAGLIHDPLRDDTMLATSGGGAFLLRGASDSAEWLPLR
VAAPAPLAQMIASVSWQYMARAEKSRVLGSLAALGQTPNLRCAAATYRAMASGHMHASVSRRTLPWDHAAGTLIVEEAGG
HVRRPDGEAWRPADIDGGLIAATDRDTWHRLRDALYG

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=213, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221625487, Length=213, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI221625507, Length=154, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI7657236, Length=216, Percent_Identity=28.2407407407407, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788882, Length=212, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=225, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193202572, Length=223, Percent_Identity=29.5964125560538, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321836, Length=265, Percent_Identity=26.7924528301887, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320493, Length=257, Percent_Identity=26.0700389105058, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24664926, Length=222, Percent_Identity=31.0810810810811, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24664922, Length=220, Percent_Identity=30.4545454545455, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357957, Length=219, Percent_Identity=27.8538812785388, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21357329, Length=227, Percent_Identity=30.8370044052863, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357303, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29220; Mature: 29220

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPDRTDLSAIAALLRDVARTIVMPRFGHIGPADLRTKSGPLDPVTVADEAAERALTEGL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEHHHHHHHHHHHHHH
RALFPDVAVIGEESVAADPALLGAVAGPGPVFVIDPIDGTQNYAAGLPLFGLMIALVEDN
HHHCCCCEEECCCHHCCCHHHHHHCCCCCCEEEECCCCCCCCHHCCCHHHHHHHHHHCCC
RTIAGLIHDPLRDDTMLATSGGGAFLLRGASDSAEWLPLRVAAPAPLAQMIASVSWQYMA
CEEEEEECCCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
RAEKSRVLGSLAALGQTPNLRCAAATYRAMASGHMHASVSRRTLPWDHAAGTLIVEEAGG
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEHHCCCCCCCCCCCCEEEEECCCC
HVRRPDGEAWRPADIDGGLIAATDRDTWHRLRDALYG
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MMPDRTDLSAIAALLRDVARTIVMPRFGHIGPADLRTKSGPLDPVTVADEAAERALTEGL
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEHHHHHHHHHHHHHH
RALFPDVAVIGEESVAADPALLGAVAGPGPVFVIDPIDGTQNYAAGLPLFGLMIALVEDN
HHHCCCCEEECCCHHCCCHHHHHHCCCCCCEEEECCCCCCCCHHCCCHHHHHHHHHHCCC
RTIAGLIHDPLRDDTMLATSGGGAFLLRGASDSAEWLPLRVAAPAPLAQMIASVSWQYMA
CEEEEEECCCCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
RAEKSRVLGSLAALGQTPNLRCAAATYRAMASGHMHASVSRRTLPWDHAAGTLIVEEAGG
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEHHCCCCCCCCCCCCEEEEECCCC
HVRRPDGEAWRPADIDGGLIAATDRDTWHRLRDALYG
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]