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The map label for this gene is cobS [H]

Identifier: 148260708

GI number: 148260708

Start: 1894437

End: 1895453

Strand: Reverse

Name: cobS [H]

Synonym: Acry_1712

Alternate gene names: 148260708

Gene position: 1895453-1894437 (Counterclockwise)

Preceding gene: 148260709

Following gene: 148260707

Centisome position: 55.93

GC content: 66.67

Gene sequence:

>1017_bases
ATGAACAATCTCGCTGCAATCGCCGAAACCCGCGGCACGCCGACCTCGGCGATCAACCTGCCGGACCGCACCGTCTCGGC
GCGCGAGGTCTTCGGCATCGAGTGCGGCTTCGAGATCCCCGCCTTCTCCGAGCGCACCGAGCACGTCCCCGAGATCGACG
CGACCTACCGCTTCGACCCGGAGACGACCATCGCCATCCTCGCCGGCTTCGCCCTCAACCGCCGGGTGATGATCCAGGGC
TATCACGGCACCGGCAAGTCGACGCATATCGAGCAGGTCGCCGCCCGCCTCAACTGGCCCTGCATCCGCGTCAATCTCGA
CAGCCACATCTCCCGCATCGACCTCGTCGGCAAGGACGCGATCGTGCTGAAGGACGGCAAGCAGGTCACCGAATTCCGCG
AGGGCCTGCTGCCCTGGGCGCTGCAGCACCCCTGCGCGCTGGTGTTCGACGAATACGACGCCGGCCGGCCGGACGTGATG
TTCGTCATCCAGCGCGTGCTGGAGGTCGAGGGCAAGCTCACCCTGCTCGACCAGAACCGCGTCATCCGCCCGCACCCGGC
CTTCCGCCTCTTCGCCACCGCCAACACGGTCGGCCTCGGCGACACCACCGGCCTCTATCACGGCACCCAGCAGATCAACC
AGGGCCAGATGGACCGCTGGAACATCGTCGCCACGCTGAACTACCTGCCGCACGGCCAGGAAGTCTCCATCGTCATGGCC
AAGCTCGGCATCACCGAGGCGGACGCGGCGGAGAAGAAGCGGATCGAGAGCATGGTCGCCCTGGCCGATCTCACCCGCGC
CGGCTTCATCAACGGCGACATCTCCACCGTGATGTCCCCGCGCACCGTCATCACCTGGGCCGAGAACGCCCGCATCTTCA
ACGATGTCGGCTTTGCCTTCCGCCTCACTTTCCTCAACAAGTGCGACGAGGCCGAGCGCGCCACCGTGGCCGAATACTAC
CAGCGCTGCTTCAACGCGGAGGTTGAAACCGGCGTGCATCCCCGCCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGAGGGTCAGCCCCGCGCCGCCGCCGGCGCCTGATCCCTTGCGCGCCGCGCCATGCCGAGTACTCTGACGACAAGA
GACCTGAGGATGATGGATCG

Downstream 100 bases:

>100_bases
TGCCGGCCGAACCCTCCCGCAGCGAGGAATTCAAGCGCGCCACCGCCGGCGCCGTCCGCGCCATCGCCGGGTCGGACGAG
GTGCAGGTCGCCTACCAGCC

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNNLAAIAETRGTPTSAINLPDRTVSAREVFGIECGFEIPAFSERTEHVPEIDATYRFDPETTIAILAGFALNRRVMIQG
YHGTGKSTHIEQVAARLNWPCIRVNLDSHISRIDLVGKDAIVLKDGKQVTEFREGLLPWALQHPCALVFDEYDAGRPDVM
FVIQRVLEVEGKLTLLDQNRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLPHGQEVSIVMA
KLGITEADAAEKKRIESMVALADLTRAGFINGDISTVMSPRTVITWAENARIFNDVGFAFRLTFLNKCDEAERATVAEYY
QRCFNAEVETGVHPRRGA

Sequences:

>Translated_338_residues
MNNLAAIAETRGTPTSAINLPDRTVSAREVFGIECGFEIPAFSERTEHVPEIDATYRFDPETTIAILAGFALNRRVMIQG
YHGTGKSTHIEQVAARLNWPCIRVNLDSHISRIDLVGKDAIVLKDGKQVTEFREGLLPWALQHPCALVFDEYDAGRPDVM
FVIQRVLEVEGKLTLLDQNRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLPHGQEVSIVMA
KLGITEADAAEKKRIESMVALADLTRAGFINGDISTVMSPRTVITWAENARIFNDVGFAFRLTFLNKCDEAERATVAEYY
QRCFNAEVETGVHPRRGA
>Mature_338_residues
MNNLAAIAETRGTPTSAINLPDRTVSAREVFGIECGFEIPAFSERTEHVPEIDATYRFDPETTIAILAGFALNRRVMIQG
YHGTGKSTHIEQVAARLNWPCIRVNLDSHISRIDLVGKDAIVLKDGKQVTEFREGLLPWALQHPCALVFDEYDAGRPDVM
FVIQRVLEVEGKLTLLDQNRVIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLPHGQEVSIVMA
KLGITEADAAEKKRIESMVALADLTRAGFINGDISTVMSPRTVITWAENARIFNDVGFAFRLTFLNKCDEAERATVAEYY
QRCFNAEVETGVHPRRGA

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=217, Percent_Identity=24.4239631336406, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076562, Length=145, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076560, Length=145, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 37628; Mature: 37628

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLAAIAETRGTPTSAINLPDRTVSAREVFGIECGFEIPAFSERTEHVPEIDATYRFDP
CCCCHHHHHCCCCCCCEECCCCCCCCHHHEEEEECCCCCCCCCCHHCCCCCCCCEEEECC
ETTIAILAGFALNRRVMIQGYHGTGKSTHIEQVAARLNWPCIRVNLDSHISRIDLVGKDA
CCCEEHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCE
IVLKDGKQVTEFREGLLPWALQHPCALVFDEYDAGRPDVMFVIQRVLEVEGKLTLLDQNR
EEEECCCHHHHHHHCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCC
VIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLPHGQEVSIVMA
EECCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCEEEEEE
KLGITEADAAEKKRIESMVALADLTRAGFINGDISTVMSPRTVITWAENARIFNDVGFAF
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCEEECCCCCEE
RLTFLNKCDEAERATVAEYYQRCFNAEVETGVHPRRGA
EEHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCC
>Mature Secondary Structure
MNNLAAIAETRGTPTSAINLPDRTVSAREVFGIECGFEIPAFSERTEHVPEIDATYRFDP
CCCCHHHHHCCCCCCCEECCCCCCCCHHHEEEEECCCCCCCCCCHHCCCCCCCCEEEECC
ETTIAILAGFALNRRVMIQGYHGTGKSTHIEQVAARLNWPCIRVNLDSHISRIDLVGKDA
CCCEEHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEECCCCE
IVLKDGKQVTEFREGLLPWALQHPCALVFDEYDAGRPDVMFVIQRVLEVEGKLTLLDQNR
EEEECCCHHHHHHHCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCC
VIRPHPAFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNIVATLNYLPHGQEVSIVMA
EECCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCEEEEEE
KLGITEADAAEKKRIESMVALADLTRAGFINGDISTVMSPRTVITWAENARIFNDVGFAF
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCEEECCCCCEE
RLTFLNKCDEAERATVAEYYQRCFNAEVETGVHPRRGA
EEHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]