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The map label for this gene is sucD [H]

Identifier: 148260622

GI number: 148260622

Start: 1794888

End: 1795763

Strand: Reverse

Name: sucD [H]

Synonym: Acry_1624

Alternate gene names: 148260622

Gene position: 1795763-1794888 (Counterclockwise)

Preceding gene: 148260623

Following gene: 148260621

Centisome position: 52.98

GC content: 68.26

Gene sequence:

>876_bases
ATGGCTATTCTCGTCAACGCCGAAACCAAGGTCATCACCCAGGGCTTCACCGGCGCGCAGGGCACCTTCCACTCCGAACA
GGCGATCGCCTACGGCACCAAGGTCATGGGCGGCGTCACCCCGGGCAAGGGCGGCACCCGCCATCTCGACCTGCCGGTGT
TCGACACCGTGGCCGAGGCCCGCGAGGCGACCGGCGCCGATGCGAGCGCGATCTACGTCCCGCCGCCCTTCGCTGCGGAC
GCCATCCTCGAGGCGATCGACGCCGAGATCCCGCTGATCGTCTGCATCACCGAGGGCATCCCGGTGCTCGACATGGTGAA
GGTCCACCGCGCGCTGTCCGGCTCGAAATCGATCCTGGTCGGGCCGAACTGCCCGGGCGTCATCACGCCGGATGCCTGCA
AGATCGGCATCATGCCGGGGCACATCCACCGCCGCGGCAAGGTCGGCATCGTCTCGCGCTCCGGCACGCTGACCTACGAG
GCGGTGGCGCAGACCACGGCGGCCGGGCTCGGCCAGTCGAGCTGTGTCGGCATCGGCGGCGACCCGGTGAAGGGGCTCGA
CTTCGTTGACGTTCTGGAAATGTTTCTGGCCGATAATGAAACCGAGGCACTGATCATGATCGGCGAGATCGGCGGCCAGA
GCGAGATCGAGGCGGCCGAGTTCCTGGCGCGCAACAAGGTGAAGAAGCCCACCGTGGGGTTCATCGCCGGCGTCACCGCG
CCGCCGGGCCGGCGCATGGGTCATGCCGGCGCCGTGATTTCCGGCGGGCGCGACACCGCGCAGGCCAAGATCGAGGCGAT
GAAGGCGGCCGGCATCCATGTGGCCGACAGTCCGGCATCGCTCGGCAGCACCATGGTCAAGGCGCTTCGCGCGTAA

Upstream 100 bases:

>100_bases
GCAAGGACATCCTCTCCAAATCCGGCCTGCCCATCATCGCGGCCGACAATCTCGCTGACGCGGCGCAGAAGATCGTCGCC
GCCGTGAAGGAGGCCGCATA

Downstream 100 bases:

>100_bases
CGAGGAGTCGGCGGGTTTGTTCATTCGTCATGGATCGGGGAGGCTTCATGCAAGGAAAGCATCCCAGAACCGAGACTTGA
CGGTGCAACGGCCTGATCGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAILVNAETKVITQGFTGAQGTFHSEQAIAYGTKVMGGVTPGKGGTRHLDLPVFDTVAEAREATGADASAIYVPPPFAAD
AILEAIDAEIPLIVCITEGIPVLDMVKVHRALSGSKSILVGPNCPGVITPDACKIGIMPGHIHRRGKVGIVSRSGTLTYE
AVAQTTAAGLGQSSCVGIGGDPVKGLDFVDVLEMFLADNETEALIMIGEIGGQSEIEAAEFLARNKVKKPTVGFIAGVTA
PPGRRMGHAGAVISGGRDTAQAKIEAMKAAGIHVADSPASLGSTMVKALRA

Sequences:

>Translated_291_residues
MAILVNAETKVITQGFTGAQGTFHSEQAIAYGTKVMGGVTPGKGGTRHLDLPVFDTVAEAREATGADASAIYVPPPFAAD
AILEAIDAEIPLIVCITEGIPVLDMVKVHRALSGSKSILVGPNCPGVITPDACKIGIMPGHIHRRGKVGIVSRSGTLTYE
AVAQTTAAGLGQSSCVGIGGDPVKGLDFVDVLEMFLADNETEALIMIGEIGGQSEIEAAEFLARNKVKKPTVGFIAGVTA
PPGRRMGHAGAVISGGRDTAQAKIEAMKAAGIHVADSPASLGSTMVKALRA
>Mature_290_residues
AILVNAETKVITQGFTGAQGTFHSEQAIAYGTKVMGGVTPGKGGTRHLDLPVFDTVAEAREATGADASAIYVPPPFAADA
ILEAIDAEIPLIVCITEGIPVLDMVKVHRALSGSKSILVGPNCPGVITPDACKIGIMPGHIHRRGKVGIVSRSGTLTYEA
VAQTTAAGLGQSSCVGIGGDPVKGLDFVDVLEMFLADNETEALIMIGEIGGQSEIEAAEFLARNKVKKPTVGFIAGVTAP
PGRRMGHAGAVISGGRDTAQAKIEAMKAAGIHVADSPASLGSTMVKALRA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=291, Percent_Identity=65.979381443299, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI38569423, Length=252, Percent_Identity=29.7619047619048, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38569421, Length=251, Percent_Identity=29.8804780876494, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786949, Length=290, Percent_Identity=65.1724137931034, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17550194, Length=291, Percent_Identity=63.573883161512, Blast_Score=355, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17553126, Length=291, Percent_Identity=63.9175257731959, Blast_Score=349, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI17557344, Length=258, Percent_Identity=29.0697674418605, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=29.8449612403101, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=52.3972602739726, Blast_Score=289, Evalue=5e-79,
Organism=Drosophila melanogaster, GI21356559, Length=289, Percent_Identity=59.1695501730104, Blast_Score=351, Evalue=4e-97,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=63.6986301369863, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281363477, Length=252, Percent_Identity=28.968253968254, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363475, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281363473, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29746; Mature: 29615

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVNAETKVITQGFTGAQGTFHSEQAIAYGTKVMGGVTPGKGGTRHLDLPVFDTVAEA
CEEEEECCCEEEECCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCCEEECCCHHHHHHHH
REATGADASAIYVPPPFAADAILEAIDAEIPLIVCITEGIPVLDMVKVHRALSGSKSILV
HHHCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPDACKIGIMPGHIHRRGKVGIVSRSGTLTYEAVAQTTAAGLGQSSCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCCEEECCC
DPVKGLDFVDVLEMFLADNETEALIMIGEIGGQSEIEAAEFLARNKVKKPTVGFIAGVTA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCC
PPGRRMGHAGAVISGGRDTAQAKIEAMKAAGIHVADSPASLGSTMVKALRA
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AILVNAETKVITQGFTGAQGTFHSEQAIAYGTKVMGGVTPGKGGTRHLDLPVFDTVAEA
EEEEECCCEEEECCCCCCCCCCCCCCHHHHCCHHHCCCCCCCCCCEEECCCHHHHHHHH
REATGADASAIYVPPPFAADAILEAIDAEIPLIVCITEGIPVLDMVKVHRALSGSKSILV
HHHCCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPDACKIGIMPGHIHRRGKVGIVSRSGTLTYEAVAQTTAAGLGQSSCVGIGG
CCCCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCCEEECCC
DPVKGLDFVDVLEMFLADNETEALIMIGEIGGQSEIEAAEFLARNKVKKPTVGFIAGVTA
CCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCC
PPGRRMGHAGAVISGGRDTAQAKIEAMKAAGIHVADSPASLGSTMVKALRA
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]