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The map label for this gene is sucC

Identifier: 148260623

GI number: 148260623

Start: 1795763

End: 1796959

Strand: Reverse

Name: sucC

Synonym: Acry_1625

Alternate gene names: 148260623

Gene position: 1796959-1795763 (Counterclockwise)

Preceding gene: 148260624

Following gene: 148260622

Centisome position: 53.02

GC content: 67.17

Gene sequence:

>1197_bases
ATGAACATACATGAATACCAGGCCAAGGAACTGCTGAAGTCCTATGGCGTCGCGGTGCTGGACGGGCACGTCGCCTGGAC
CGGCGAGGAGGCCGCCGAGGCGGCGCGCAAGCTCCCCGGCCCGGTTTATGTCGTGAAGTCGCAGATCCATGCCGGCGGCC
GCGGCGCCGGCCATTTCAAGGACGATCCGGAGGGCAAGGGCGGTGTCCGCCTCGCCAAGTCGCCCGAGGAGGTTGCCGCC
GCCGCCGAGGCGATGCTGGGCAACACGCTGGTGACCAAGCAGACCGGCCCGGCCGGCCGCGTCGTCCGCCGCGTCTATGT
CGAGGCCGGCTGCGACATCAAGCGCGAGCTCTACCTCTCGCTGCTGGTCGACCGCGCGAAATCCGAGATCGTCATCATGG
CCTCGACCGAGGGCGGCATGGAGATCGAGGAAGTCGCCGAGAAGCATCCCGAGAAGATCCTCCGCGTCGCGGTCGATCCG
GCGAGCGGCATCTCCGGCTTCCACGCCCGCCGCCTCGGCTTCGGCCTCGGGCTCGACGCCACCCAGATGAAGGCCTTCGC
GAAATTCGTGAACGCGATGTACAAGGCCTTCGTCGCGCTCGACTGCGCGATCGTCGAGATCAACCCGCTGGTCGTCACCG
GCGCCGGCGAGGTGGTCGCTCTCGACGCCAAGGTCAGCTTCGACGACAATGCGCTCTACCGTCACCCCGATCTCGAGAAG
CTGCGCGACGAGGCCGAGGAAGACCCGAAGGAACTCGAGGCCGCCAAGCACAGCCTGAACTACGTGGCGCTGGACGGCTC
GATCGGCTGCATGGTCAACGGCGCCGGCCTCGCGATGGCGACGATGGACATCATCAAGCTCTACGGCGCGGAGCCGGCGA
ACTTCCTCGATGTCGGCGGCGGGGCGACCAAGGAGCGCGTCACCGCGGCCTTCAAGATCATCCTGTCGGACCCGAATGTC
GAAGGCATCCTGGTCAACATCTTCGGCGGCATCATGCGCTGCGACGTGATCGCCGAGGGCGTGGTCGCCGCGGCGCGCGA
GGTCTCGCTCTCGGTGCCGCTGGTCGTCCGCCTCGAGGGCACCAACGTGCAGCTCGGCAAGGACATCCTCTCCAAATCCG
GCCTGCCCATCATCGCGGCCGACAATCTCGCTGACGCGGCGCAGAAGATCGTCGCCGCCGTGAAGGAGGCCGCATAA

Upstream 100 bases:

>100_bases
CATTGGTCTAGGCCGCACGACGACGGAACCGCCCGGGACGGACGGCGCGCAAGGCGCCGGGTTTCGAGTGACAGGCGAGT
GATCACCGTATGGGGGCCCC

Downstream 100 bases:

>100_bases
TGGCTATTCTCGTCAACGCCGAAACCAAGGTCATCACCCAGGGCTTCACCGGCGCGCAGGGCACCTTCCACTCCGAACAG
GCGATCGCCTACGGCACCAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNIHEYQAKELLKSYGVAVLDGHVAWTGEEAAEAARKLPGPVYVVKSQIHAGGRGAGHFKDDPEGKGGVRLAKSPEEVAA
AAEAMLGNTLVTKQTGPAGRVVRRVYVEAGCDIKRELYLSLLVDRAKSEIVIMASTEGGMEIEEVAEKHPEKILRVAVDP
ASGISGFHARRLGFGLGLDATQMKAFAKFVNAMYKAFVALDCAIVEINPLVVTGAGEVVALDAKVSFDDNALYRHPDLEK
LRDEAEEDPKELEAAKHSLNYVALDGSIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKERVTAAFKIILSDPNV
EGILVNIFGGIMRCDVIAEGVVAAAREVSLSVPLVVRLEGTNVQLGKDILSKSGLPIIAADNLADAAQKIVAAVKEAA

Sequences:

>Translated_398_residues
MNIHEYQAKELLKSYGVAVLDGHVAWTGEEAAEAARKLPGPVYVVKSQIHAGGRGAGHFKDDPEGKGGVRLAKSPEEVAA
AAEAMLGNTLVTKQTGPAGRVVRRVYVEAGCDIKRELYLSLLVDRAKSEIVIMASTEGGMEIEEVAEKHPEKILRVAVDP
ASGISGFHARRLGFGLGLDATQMKAFAKFVNAMYKAFVALDCAIVEINPLVVTGAGEVVALDAKVSFDDNALYRHPDLEK
LRDEAEEDPKELEAAKHSLNYVALDGSIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKERVTAAFKIILSDPNV
EGILVNIFGGIMRCDVIAEGVVAAAREVSLSVPLVVRLEGTNVQLGKDILSKSGLPIIAADNLADAAQKIVAAVKEAA
>Mature_398_residues
MNIHEYQAKELLKSYGVAVLDGHVAWTGEEAAEAARKLPGPVYVVKSQIHAGGRGAGHFKDDPEGKGGVRLAKSPEEVAA
AAEAMLGNTLVTKQTGPAGRVVRRVYVEAGCDIKRELYLSLLVDRAKSEIVIMASTEGGMEIEEVAEKHPEKILRVAVDP
ASGISGFHARRLGFGLGLDATQMKAFAKFVNAMYKAFVALDCAIVEINPLVVTGAGEVVALDAKVSFDDNALYRHPDLEK
LRDEAEEDPKELEAAKHSLNYVALDGSIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKERVTAAFKIILSDPNV
EGILVNIFGGIMRCDVIAEGVVAAAREVSLSVPLVVRLEGTNVQLGKDILSKSGLPIIAADNLADAAQKIVAAVKEAA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI157779135, Length=385, Percent_Identity=48.3116883116883, Blast_Score=347, Evalue=9e-96,
Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=46.0358056265985, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI294862256, Length=361, Percent_Identity=47.9224376731302, Blast_Score=324, Evalue=9e-89,
Organism=Escherichia coli, GI1786948, Length=395, Percent_Identity=54.6835443037975, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=46.4467005076142, Blast_Score=354, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=45.1282051282051, Blast_Score=335, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=47.7157360406091, Blast_Score=365, Evalue=1e-102,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=49.873417721519, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI161078106, Length=387, Percent_Identity=49.0956072351421, Blast_Score=356, Evalue=1e-98,
Organism=Drosophila melanogaster, GI24645208, Length=387, Percent_Identity=49.0956072351421, Blast_Score=356, Evalue=1e-98,
Organism=Drosophila melanogaster, GI281361397, Length=388, Percent_Identity=49.2268041237113, Blast_Score=354, Evalue=6e-98,
Organism=Drosophila melanogaster, GI281361395, Length=388, Percent_Identity=49.2268041237113, Blast_Score=354, Evalue=6e-98,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_ACICJ (A5FYZ9)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234750.1
- ProteinModelPortal:   A5FYZ9
- SMR:   A5FYZ9
- STRING:   A5FYZ9
- GeneID:   5159941
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1625
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   TNVHEAQ
- BioCyc:   ACRY349163:ACRY_1625-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42009; Mature: 42009

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKELLKSYGVAVLDGHVAWTGEEAAEAARKLPGPVYVVKSQIHAGGRGAGHFK
CCCHHHHHHHHHHHCCEEEEECEEEECCHHHHHHHHHCCCCEEEEEEHHCCCCCCCCCCC
DDPEGKGGVRLAKSPEEVAAAAEAMLGNTLVTKQTGPAGRVVRRVYVEAGCDIKRELYLS
CCCCCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHH
LLVDRAKSEIVIMASTEGGMEIEEVAEKHPEKILRVAVDPASGISGFHARRLGFGLGLDA
HHHHHCCCCEEEEEECCCCCCHHHHHHHCHHHEEEEEECCCCCCCCHHHHHHCCCCCCCH
TQMKAFAKFVNAMYKAFVALDCAIVEINPLVVTGAGEVVALDAKVSFDDNALYRHPDLEK
HHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEECCCCEEEEEEEEECCCCCEECCCCHHH
LRDEAEEDPKELEAAKHSLNYVALDGSIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGG
HHHHHHCCHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCC
GATKERVTAAFKIILSDPNVEGILVNIFGGIMRCDVIAEGVVAAAREVSLSVPLVVRLEG
CCCHHHHEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
TNVQLGKDILSKSGLPIIAADNLADAAQKIVAAVKEAA
CCEECCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKELLKSYGVAVLDGHVAWTGEEAAEAARKLPGPVYVVKSQIHAGGRGAGHFK
CCCHHHHHHHHHHHCCEEEEECEEEECCHHHHHHHHHCCCCEEEEEEHHCCCCCCCCCCC
DDPEGKGGVRLAKSPEEVAAAAEAMLGNTLVTKQTGPAGRVVRRVYVEAGCDIKRELYLS
CCCCCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHH
LLVDRAKSEIVIMASTEGGMEIEEVAEKHPEKILRVAVDPASGISGFHARRLGFGLGLDA
HHHHHCCCCEEEEEECCCCCCHHHHHHHCHHHEEEEEECCCCCCCCHHHHHHCCCCCCCH
TQMKAFAKFVNAMYKAFVALDCAIVEINPLVVTGAGEVVALDAKVSFDDNALYRHPDLEK
HHHHHHHHHHHHHHHHHHHHEEEEEEECCEEEECCCCEEEEEEEEECCCCCEECCCCHHH
LRDEAEEDPKELEAAKHSLNYVALDGSIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGG
HHHHHHCCHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCC
GATKERVTAAFKIILSDPNVEGILVNIFGGIMRCDVIAEGVVAAAREVSLSVPLVVRLEG
CCCHHHHEEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
TNVQLGKDILSKSGLPIIAADNLADAAQKIVAAVKEAA
CCEECCHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA