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The map label for this gene is yhcK [H]

Identifier: 148260602

GI number: 148260602

Start: 1771226

End: 1772338

Strand: Reverse

Name: yhcK [H]

Synonym: Acry_1604

Alternate gene names: 148260602

Gene position: 1772338-1771226 (Counterclockwise)

Preceding gene: 148260603

Following gene: 148260600

Centisome position: 52.29

GC content: 70.53

Gene sequence:

>1113_bases
ATGGGGCTCACATCTTTCTATCTGTTCTTCGATGGCATGATACTGGTCGGCGGCACCCTGCTGCTGGCCACGGGAATGCT
GTCCGGCTGCGCCACGCTGAAATGGTGGAGCCTGAGCTATTTCACCGTGGCGGCCGGGATTGCGACGGTGGTTTTCGGGC
ACGCGGCCTGGCCCTGGCTCGGCTACGGGTTGGGGCCGGGGCTGAATCTCGCCGGGTTCGGCGTCATGTGGGCGGGGGCG
CGGCGGCTGAGGGGGCGGCGCGCGGCGCCCTGGCAGGTGCTGCTGCCCGGCGTCGTCTGGTTGGCGGTCAGCGCGGTGCT
GCCCTTCGGCGACGCGCCGTGGCTGCGGATGGTGACGCAGACGCTGTTCATCGAGGCGATTTTCGGACTGATCCTGGCCG
AGATCCTGCGGGCGCCGGTCCGCGCGCTGGCGCGGCTTCCGCTGGCGGGGGCGACGTTCGGGCATGCGATCTTCGTTCTC
GTGCGCGCGGTCGCCCTGCTGTTCTACGGCAGCCCGGCGGTGTACCGCTTCTGGCTCTACGGCACGGCGATCGAGGGCAT
GCTGTTCATGTTCTGCGACGCGCTGCTGATCAGCCATCTGGTCCGCTCGTGGCGCGAACACGACCTGCACGACGTCGCGC
GCACCGATTTCCTGACCGGCGTGCTGAACCGCCGCGGCTTTACCGCACGCGCGGAGCGCTGCCTGCGGGAGGCGCCTTGC
ATGCTGCTGGTGCTGGATATCGACGGGTTCAAGGGAATCAACGACACGCTCGGCCATGGCGAGGGCGACCGGCTGCTGCG
CGAGCTTGGCCGGATCTGCGTGGAGAGCGTGCGGGAAGGCGACGTGGTCGGGCGGCTGGGGGGCGACGAATTCGCGATCC
TGATCGTCGGCGGCTCGGCGGAGGTCGCGGCGGCGATCGCGCAGCGGATCCGCCTTGCCTTCGCGCAGACGCGGGTCGCG
CGCGGGCTGGCCGCCGCGGTCAGCATCGGGATCAGCGGTGCCGGGGCCGGCGGCGCCACGCTCGACGACCTGCTGGTGCA
GGCGGATATGCGGCTGTACCGGGCGAAGGACGAGCGGCCGGCATTGGGACCGGCCATGCTCCGGGCCGGCTGA

Upstream 100 bases:

>100_bases
CCTTAAGAACTGCATGTTTTCAGTCTGGTCATAAGAATTGGTGGCCTTCGTTCGGCCTGTATTTGGGCAGGTCTAAGCTG
AATCGCCTGGGCATCGGGGA

Downstream 100 bases:

>100_bases
ACGCTCCATTCTCATTTTGAAATCGTAACGATAAGGGCGTGCCGGGATGCGGCTGCTCAGGCGCGAAACGCGGCGGGGCG
GGGCGGGCGGAAGGGACGGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MGLTSFYLFFDGMILVGGTLLLATGMLSGCATLKWWSLSYFTVAAGIATVVFGHAAWPWLGYGLGPGLNLAGFGVMWAGA
RRLRGRRAAPWQVLLPGVVWLAVSAVLPFGDAPWLRMVTQTLFIEAIFGLILAEILRAPVRALARLPLAGATFGHAIFVL
VRAVALLFYGSPAVYRFWLYGTAIEGMLFMFCDALLISHLVRSWREHDLHDVARTDFLTGVLNRRGFTARAERCLREAPC
MLLVLDIDGFKGINDTLGHGEGDRLLRELGRICVESVREGDVVGRLGGDEFAILIVGGSAEVAAAIAQRIRLAFAQTRVA
RGLAAAVSIGISGAGAGGATLDDLLVQADMRLYRAKDERPALGPAMLRAG

Sequences:

>Translated_370_residues
MGLTSFYLFFDGMILVGGTLLLATGMLSGCATLKWWSLSYFTVAAGIATVVFGHAAWPWLGYGLGPGLNLAGFGVMWAGA
RRLRGRRAAPWQVLLPGVVWLAVSAVLPFGDAPWLRMVTQTLFIEAIFGLILAEILRAPVRALARLPLAGATFGHAIFVL
VRAVALLFYGSPAVYRFWLYGTAIEGMLFMFCDALLISHLVRSWREHDLHDVARTDFLTGVLNRRGFTARAERCLREAPC
MLLVLDIDGFKGINDTLGHGEGDRLLRELGRICVESVREGDVVGRLGGDEFAILIVGGSAEVAAAIAQRIRLAFAQTRVA
RGLAAAVSIGISGAGAGGATLDDLLVQADMRLYRAKDERPALGPAMLRAG
>Mature_369_residues
GLTSFYLFFDGMILVGGTLLLATGMLSGCATLKWWSLSYFTVAAGIATVVFGHAAWPWLGYGLGPGLNLAGFGVMWAGAR
RLRGRRAAPWQVLLPGVVWLAVSAVLPFGDAPWLRMVTQTLFIEAIFGLILAEILRAPVRALARLPLAGATFGHAIFVLV
RAVALLFYGSPAVYRFWLYGTAIEGMLFMFCDALLISHLVRSWREHDLHDVARTDFLTGVLNRRGFTARAERCLREAPCM
LLVLDIDGFKGINDTLGHGEGDRLLRELGRICVESVREGDVVGRLGGDEFAILIVGGSAEVAAAIAQRIRLAFAQTRVAR
GLAAAVSIGISGAGAGGATLDDLLVQADMRLYRAKDERPALGPAMLRAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081974, Length=189, Percent_Identity=32.2751322751323, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=34.0659340659341, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI145693134, Length=149, Percent_Identity=38.255033557047, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=34.1614906832298, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=28.6407766990291, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87082007, Length=151, Percent_Identity=33.7748344370861, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788381, Length=156, Percent_Identity=34.6153846153846, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787802, Length=152, Percent_Identity=34.8684210526316, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787541, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=193, Percent_Identity=29.0155440414508, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787056, Length=152, Percent_Identity=32.8947368421053, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=32.9113924050633, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 39786; Mature: 39655

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHCCC
>Mature Secondary Structure 
GLTSFYLFFDGMILVGGTLLLATGMLSGCATLKWWSLSYFTVAAGIATVVFGHAAWPWL
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GYGLGPGLNLAGFGVMWAGARRLRGRRAAPWQVLLPGVVWLAVSAVLPFGDAPWLRMVTQ
HCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
TLFIEAIFGLILAEILRAPVRALARLPLAGATFGHAIFVLVRAVALLFYGSPAVYRFWLY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GTAIEGMLFMFCDALLISHLVRSWREHDLHDVARTDFLTGVLNRRGFTARAERCLREAPC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCE
MLLVLDIDGFKGINDTLGHGEGDRLLRELGRICVESVREGDVVGRLGGDEFAILIVGGSA
EEEEEECCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCH
EVAAAIAQRIRLAFAQTRVARGLAAAVSIGISGAGAGGATLDDLLVQADMRLYRAKDERP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ALGPAMLRAG
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]