Click here to switch to the map view.

The map label for this gene is yrpG [H]

Identifier: 148260459

GI number: 148260459

Start: 1622344

End: 1623396

Strand: Reverse

Name: yrpG [H]

Synonym: Acry_1459

Alternate gene names: 148260459

Gene position: 1623396-1622344 (Counterclockwise)

Preceding gene: 148260462

Following gene: 148260458

Centisome position: 47.9

GC content: 65.05

Gene sequence:

>1053_bases
ATGGACTACCGTCAGCTCGGCCGATCCGGCCTGAAGATTTCAACGCTGACGCTCGGCACCATGACGATGGGCGGGCGCGG
CGTGTTCGAGAAGGTTGGCAATGTCGGGCGTGCCGAGGCGCGTCGGCAGATCGACATGTGCGTCGATGCCGGCGTGAACC
TTCTTGATACGGCCGACATCTATTCCACGGGCGGTTCCGAGGAGATCATCGGCGAGGCTCTGGGCGGTCAGCGGCCTCAG
GGACTGCTGATCGCGACCAAGGTAAGGTTTCCGATGGGGAAGGGGCCGAACGACCGCGGTCTGTCGCGCCATCACATCAT
CACCGCCTGCGAGGCCAGCCTGAAGCGGTTGCGCACTGACGTGATCGACCTGTACCAGGTGCACGAATGGGACGGGATCA
CACCGCTCGACGAGACGATGCAGGCGCTCGACACACTGATTCGTGACGGCAAGGTGCGCTACATCGGCTGCTCCAACTAC
TCGGCATGGCATGTGATGAAGGCGCTGGCCATCGCCGAGTCGGCGCATCGCGAACGCTTCGTGTGCCAGCAGATCCATTA
CACGCTGGAGGCGCGGGAGGCAGAGAACGAGCTGATCCCGCTCGCCATCGATCAGGGGCTCGGCGTGCTCGTCTGGAGTC
CGCTCGCCGGCGGCCTGCTCTCCGGCAAGCACCGTCGCAACCAGGAAACGCCGGCAGGTACCCGCCAGCTCGCCGGTTGG
AGTGAGCCGCCGATCCATGACGAGAGCCGCCTCTGGAACATCGTCGAGGCTCTCATTGAAGTGGCAGGCGCGCACGGCGT
TTCTGCGGCGCAGGTCGCCCTTGCCTGGCTGCTCGGTCGGCCCGCGGTCACCTCGCTGGTGATCGGCGCGCGCAACGAGC
AACAATTGGCGGACAATCTCCGCGCCGCAACGCTCGTGCTGACCAAGGAGGAGCGATCGATGCTCGATGCGGTCAGCCAG
CGTCCGTTGCAATATCCCTACTGGCATCAGGCGCAGACCGCGAGGGATCGTCTCGGCCCGGCCGATCTCGCCTTGCTGGG
ACCGCATCTCTGA

Upstream 100 bases:

>100_bases
GCCTACGTGACAGTCATCGGTCCGCGCCTTGATGGCGCGCCCTTGTGCCGGCCCATGCACGGCACGACATCTGGCGTTCC
GAAAGCAGGGAGCACTTCCG

Downstream 100 bases:

>100_bases
GCGACGTGTGAGCCGCCCGCCAGCCGTAGAAACCTCAATTCCTGCCCGGCTCGACCGGCTGGCCTGGGGGCGGTTTCACT
GGCTGGTGGTTGTGGCCCTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MDYRQLGRSGLKISTLTLGTMTMGGRGVFEKVGNVGRAEARRQIDMCVDAGVNLLDTADIYSTGGSEEIIGEALGGQRPQ
GLLIATKVRFPMGKGPNDRGLSRHHIITACEASLKRLRTDVIDLYQVHEWDGITPLDETMQALDTLIRDGKVRYIGCSNY
SAWHVMKALAIAESAHRERFVCQQIHYTLEAREAENELIPLAIDQGLGVLVWSPLAGGLLSGKHRRNQETPAGTRQLAGW
SEPPIHDESRLWNIVEALIEVAGAHGVSAAQVALAWLLGRPAVTSLVIGARNEQQLADNLRAATLVLTKEERSMLDAVSQ
RPLQYPYWHQAQTARDRLGPADLALLGPHL

Sequences:

>Translated_350_residues
MDYRQLGRSGLKISTLTLGTMTMGGRGVFEKVGNVGRAEARRQIDMCVDAGVNLLDTADIYSTGGSEEIIGEALGGQRPQ
GLLIATKVRFPMGKGPNDRGLSRHHIITACEASLKRLRTDVIDLYQVHEWDGITPLDETMQALDTLIRDGKVRYIGCSNY
SAWHVMKALAIAESAHRERFVCQQIHYTLEAREAENELIPLAIDQGLGVLVWSPLAGGLLSGKHRRNQETPAGTRQLAGW
SEPPIHDESRLWNIVEALIEVAGAHGVSAAQVALAWLLGRPAVTSLVIGARNEQQLADNLRAATLVLTKEERSMLDAVSQ
RPLQYPYWHQAQTARDRLGPADLALLGPHL
>Mature_350_residues
MDYRQLGRSGLKISTLTLGTMTMGGRGVFEKVGNVGRAEARRQIDMCVDAGVNLLDTADIYSTGGSEEIIGEALGGQRPQ
GLLIATKVRFPMGKGPNDRGLSRHHIITACEASLKRLRTDVIDLYQVHEWDGITPLDETMQALDTLIRDGKVRYIGCSNY
SAWHVMKALAIAESAHRERFVCQQIHYTLEAREAENELIPLAIDQGLGVLVWSPLAGGLLSGKHRRNQETPAGTRQLAGW
SEPPIHDESRLWNIVEALIEVAGAHGVSAAQVALAWLLGRPAVTSLVIGARNEQQLADNLRAATLVLTKEERSMLDAVSQ
RPLQYPYWHQAQTARDRLGPADLALLGPHL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=33.6336336336336, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI27436969, Length=335, Percent_Identity=34.3283582089552, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=33.6336336336336, Blast_Score=164, Evalue=9e-41,
Organism=Homo sapiens, GI4504825, Length=333, Percent_Identity=34.2342342342342, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI27436971, Length=308, Percent_Identity=32.4675324675325, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI223718702, Length=320, Percent_Identity=31.25, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI41327764, Length=324, Percent_Identity=29.0123456790123, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI41152114, Length=318, Percent_Identity=29.559748427673, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223718708, Length=174, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=37.6175548589342, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=34.375, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=30.9090909090909, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788070, Length=336, Percent_Identity=29.7619047619048, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=31.6363636363636, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI48994888, Length=284, Percent_Identity=27.4647887323944, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=335, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=333, Percent_Identity=32.7327327327327, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=28.3987915407855, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=306, Percent_Identity=28.7581699346405, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319951, Length=333, Percent_Identity=28.8288288288288, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=29.0196078431373, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321052, Length=163, Percent_Identity=30.6748466257669, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640980, Length=351, Percent_Identity=26.4957264957265, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45549126, Length=351, Percent_Identity=26.4957264957265, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=29.7297297297297, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646159, Length=337, Percent_Identity=27.893175074184, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38353; Mature: 38353

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRQLGRSGLKISTLTLGTMTMGGRGVFEKVGNVGRAEARRQIDMCVDAGVNLLDTADI
CCHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHH
YSTGGSEEIIGEALGGQRPQGLLIATKVRFPMGKGPNDRGLSRHHIITACEASLKRLRTD
HCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VIDLYQVHEWDGITPLDETMQALDTLIRDGKVRYIGCSNYSAWHVMKALAIAESAHRERF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VCQQIHYTLEAREAENELIPLAIDQGLGVLVWSPLAGGLLSGKHRRNQETPAGTRQLAGW
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHCHHHCCCCCCCCCCCCCHHHHCCC
SEPPIHDESRLWNIVEALIEVAGAHGVSAAQVALAWLLGRPAVTSLVIGARNEQQLADNL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
RAATLVLTKEERSMLDAVSQRPLQYPYWHQAQTARDRLGPADLALLGPHL
HHEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHCCCCC
>Mature Secondary Structure
MDYRQLGRSGLKISTLTLGTMTMGGRGVFEKVGNVGRAEARRQIDMCVDAGVNLLDTADI
CCHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHH
YSTGGSEEIIGEALGGQRPQGLLIATKVRFPMGKGPNDRGLSRHHIITACEASLKRLRTD
HCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VIDLYQVHEWDGITPLDETMQALDTLIRDGKVRYIGCSNYSAWHVMKALAIAESAHRERF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VCQQIHYTLEAREAENELIPLAIDQGLGVLVWSPLAGGLLSGKHRRNQETPAGTRQLAGW
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCHHCHHHCCCCCCCCCCCCCHHHHCCC
SEPPIHDESRLWNIVEALIEVAGAHGVSAAQVALAWLLGRPAVTSLVIGARNEQQLADNL
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
RAATLVLTKEERSMLDAVSQRPLQYPYWHQAQTARDRLGPADLALLGPHL
HHEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]