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The map label for this gene is moeA [H]

Identifier: 148260233

GI number: 148260233

Start: 1369270

End: 1370475

Strand: Reverse

Name: moeA [H]

Synonym: Acry_1230

Alternate gene names: 148260233

Gene position: 1370475-1369270 (Counterclockwise)

Preceding gene: 148260234

Following gene: 148260228

Centisome position: 40.44

GC content: 76.37

Gene sequence:

>1206_bases
ATGATCAGCGTCGGCGAGGCACGGGAGCGGATTCTGGCGCTGCTGGCGCCGACGGGCGCCGAGATCGTGCCGCTGGCGGC
GGCTGCGGGGCGGGTGCTGGCCGAGCCGGTGGTCGCACGGCTGACCCAGCCGCCGCACGATGTTTCGGCGATGGACGGGT
TCGCGCTGCGCGCCGCCGATGGCGTGGCGGGGATGCGGCTGCGGGTGATCGGCGCGGCGCCGGCGGGGCACCCGTTCGCG
GGCACGGTGGGGCCGGGCGAGGCGGTGCGGCTGTTCACCGGCAGCGTGGTGCCGGCGGGGGCGGACGCCATCGTCATCCA
GGAGGATACCGAGCATGACGACGCCTCGGTGACGCTGCGCGAGGCGGCGCGGCCGGGGCGGCATATCCGCCGGGCGGGGC
AGGATTTCGCCGCGGGCGAGACGCTGCTGGCGGCGGGGCGGGTGCTGGGCGCGCGCGATATCGGGCTGGCGGCGGCGGCG
AACCATCCCTGGCTCGCGGTGCGGCGGCGGCCGGTGGTCGCGGTGCTGGCGACCGGCGACGAGATCGCCATGCCGGGCGA
GCCGATTCCGCCGGGCGGGATCGTCAGTTCCAATTCGCACGCGCTGGCGGCCTATATCCGCGCGGCGGGCGGCGAGGCGG
TGATCCTGCCGGTGGCGCCGGACGACCGCGCCGCGATTGGCGCGGCGGCGGCGGCGGCGGCGCGGGCCGACCTGCTGGTG
ACGACCGGGGGGGCGAGCGTCGGCGCGCATGACCTGGTGCAGGCGGGCTTGGCCGAGCGGGGGCTCGACGTCGATTTCTG
GAAGATCGCGATGCGGCCGGGCAAGCCGCTGATGGCGGGGATGCTGGGCGGCGTGCCGGTGCTGGGACTGCCGGGGAATC
CGGTGTCGGCGCTGGTCTGCGCGGTGCTGTTCCTTGGCCCCGCGATCGCGCGGCTGACCGGGCGGCCGGACGAGGCGCCG
CCGACCGAGCCCGCGCGCTGCACCGTGGCGCTGGCGGCGAACGACCACCGGGCCGATCATCTGCGGGCGACGCTGGCGCG
TGATGAGGCGGGCGGCTGGAGCGTGACGCCGTTCCCGGTGCAGGATTCGGCGATGCTGAGCCGGCTGGCGCAGGCCGATG
CGCTGCTGCTGCGCGCGCCGGATGCGCCGGCCGAGCCGGAAGGGGCGATGGTGCGGGTGATCAGGCTCGACTCATGCGGG
ATGTGA

Upstream 100 bases:

>100_bases
CGACATGCTGAAGGCGGCGGAGCGGGAGATGCGGATCGAGGGGTTGCGGGTGATCCGCAAGTCCGGCGGGAAATCGGGCG
ATTTCAGGCAGGAGTGAGCG

Downstream 100 bases:

>100_bases
GCGCCTAATCGGCTGGATCAGGAATTTCCCATAGGCAACTGATTTTTCGGAAAACCGGCCGGACCAGAAGTCCGGCCGAG
GACGTTCGGTCAGCCGGCGA

Product: molybdenum cofactor synthesis domain-containing protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MISVGEARERILALLAPTGAEIVPLAAAAGRVLAEPVVARLTQPPHDVSAMDGFALRAADGVAGMRLRVIGAAPAGHPFA
GTVGPGEAVRLFTGSVVPAGADAIVIQEDTEHDDASVTLREAARPGRHIRRAGQDFAAGETLLAAGRVLGARDIGLAAAA
NHPWLAVRRRPVVAVLATGDEIAMPGEPIPPGGIVSSNSHALAAYIRAAGGEAVILPVAPDDRAAIGAAAAAAARADLLV
TTGGASVGAHDLVQAGLAERGLDVDFWKIAMRPGKPLMAGMLGGVPVLGLPGNPVSALVCAVLFLGPAIARLTGRPDEAP
PTEPARCTVALAANDHRADHLRATLARDEAGGWSVTPFPVQDSAMLSRLAQADALLLRAPDAPAEPEGAMVRVIRLDSCG
M

Sequences:

>Translated_401_residues
MISVGEARERILALLAPTGAEIVPLAAAAGRVLAEPVVARLTQPPHDVSAMDGFALRAADGVAGMRLRVIGAAPAGHPFA
GTVGPGEAVRLFTGSVVPAGADAIVIQEDTEHDDASVTLREAARPGRHIRRAGQDFAAGETLLAAGRVLGARDIGLAAAA
NHPWLAVRRRPVVAVLATGDEIAMPGEPIPPGGIVSSNSHALAAYIRAAGGEAVILPVAPDDRAAIGAAAAAAARADLLV
TTGGASVGAHDLVQAGLAERGLDVDFWKIAMRPGKPLMAGMLGGVPVLGLPGNPVSALVCAVLFLGPAIARLTGRPDEAP
PTEPARCTVALAANDHRADHLRATLARDEAGGWSVTPFPVQDSAMLSRLAQADALLLRAPDAPAEPEGAMVRVIRLDSCG
M
>Mature_401_residues
MISVGEARERILALLAPTGAEIVPLAAAAGRVLAEPVVARLTQPPHDVSAMDGFALRAADGVAGMRLRVIGAAPAGHPFA
GTVGPGEAVRLFTGSVVPAGADAIVIQEDTEHDDASVTLREAARPGRHIRRAGQDFAAGETLLAAGRVLGARDIGLAAAA
NHPWLAVRRRPVVAVLATGDEIAMPGEPIPPGGIVSSNSHALAAYIRAAGGEAVILPVAPDDRAAIGAAAAAAARADLLV
TTGGASVGAHDLVQAGLAERGLDVDFWKIAMRPGKPLMAGMLGGVPVLGLPGNPVSALVCAVLFLGPAIARLTGRPDEAP
PTEPARCTVALAANDHRADHLRATLARDEAGGWSVTPFPVQDSAMLSRLAQADALLLRAPDAPAEPEGAMVRVIRLDSCG
M

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=405, Percent_Identity=36.0493827160494, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI66932975, Length=405, Percent_Identity=36.0493827160494, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1787049, Length=384, Percent_Identity=35.15625, Blast_Score=211, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI25147659, Length=395, Percent_Identity=29.620253164557, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17562606, Length=370, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17136978, Length=420, Percent_Identity=25.7142857142857, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24638841, Length=420, Percent_Identity=25.7142857142857, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 40644; Mature: 40644

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVGEARERILALLAPTGAEIVPLAAAAGRVLAEPVVARLTQPPHDVSAMDGFALRAAD
CCCCCHHHHHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECC
GVAGMRLRVIGAAPAGHPFAGTVGPGEAVRLFTGSVVPAGADAIVIQEDTEHDDASVTLR
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEHH
EAARPGRHIRRAGQDFAAGETLLAAGRVLGARDIGLAAAANHPWLAVRRRPVVAVLATGD
HHCCCCHHHHHCCCCHHCCHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCEEEEEECCC
EIAMPGEPIPPGGIVSSNSHALAAYIRAAGGEAVILPVAPDDRAAIGAAAAAAARADLLV
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEE
TTGGASVGAHDLVQAGLAERGLDVDFWKIAMRPGKPLMAGMLGGVPVLGLPGNPVSALVC
EECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCHHHHHHH
AVLFLGPAIARLTGRPDEAPPTEPARCTVALAANDHRADHLRATLARDEAGGWSVTPFPV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
QDSAMLSRLAQADALLLRAPDAPAEPEGAMVRVIRLDSCGM
CHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MISVGEARERILALLAPTGAEIVPLAAAAGRVLAEPVVARLTQPPHDVSAMDGFALRAAD
CCCCCHHHHHHEEEECCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHCCCEEEEECC
GVAGMRLRVIGAAPAGHPFAGTVGPGEAVRLFTGSVVPAGADAIVIQEDTEHDDASVTLR
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEHH
EAARPGRHIRRAGQDFAAGETLLAAGRVLGARDIGLAAAANHPWLAVRRRPVVAVLATGD
HHCCCCHHHHHCCCCHHCCHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCEEEEEECCC
EIAMPGEPIPPGGIVSSNSHALAAYIRAAGGEAVILPVAPDDRAAIGAAAAAAARADLLV
CCCCCCCCCCCCCEECCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEE
TTGGASVGAHDLVQAGLAERGLDVDFWKIAMRPGKPLMAGMLGGVPVLGLPGNPVSALVC
EECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCEEECCCCHHHHHHH
AVLFLGPAIARLTGRPDEAPPTEPARCTVALAANDHRADHLRATLARDEAGGWSVTPFPV
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
QDSAMLSRLAQADALLLRAPDAPAEPEGAMVRVIRLDSCGM
CHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]