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The map label for this gene is moaC

Identifier: 148260234

GI number: 148260234

Start: 1370479

End: 1370955

Strand: Reverse

Name: moaC

Synonym: Acry_1231

Alternate gene names: 148260234

Gene position: 1370955-1370479 (Counterclockwise)

Preceding gene: 148260235

Following gene: 148260233

Centisome position: 40.45

GC content: 71.7

Gene sequence:

>477_bases
ATGAGCCGCCTCACCCATATCGACGAGCGGGGGGCGGCGCGGATGGTCGACGTCTCCGGCAAGGCGGAGACGGCGCGGGA
GGCGACCGCCGCCTGCCACGTGACGATGCGGGCGGAGACGCTGGCGCTGGTGACCGAAGGCACGGCGAAGAAGGGCGACG
TGCTGGCGACGGCGCGGATCGCCGGGATCATGGCGGCGAAGCGGACCTCGGAGCTGATCCCGCTCTGCCATCCGCTGGCG
ATCGCCGGGGTGACGCTGGAGCTGGAGCCGGACGCGGCGCTGCCGGGCATCCGCATCGCGGCGACGGTGAAGACCACCGG
GCCGACCGGGGTGGAGATGGAGGCGCTGACCGCTGCCTCGGTCGCGGCGCTGACGGTGTACGACATGCTGAAGGCGGCGG
AGCGGGAGATGCGGATCGAGGGGTTGCGGGTGATCCGCAAGTCCGGCGGGAAATCGGGCGATTTCAGGCAGGAGTGA

Upstream 100 bases:

>100_bases
GGCTGAAGGCGGTGGGGGTGCAGGGCATCCTGGTCGGCGAGAGCCTGATGCGGCAGGACGACATCGTCGCCGCGACGCGC
CGGCTGCTCGGGCTCGGGGC

Downstream 100 bases:

>100_bases
GCGATGATCAGCGTCGGCGAGGCACGGGAGCGGATTCTGGCGCTGCTGGCGCCGACGGGCGCCGAGATCGTGCCGCTGGC
GGCGGCTGCGGGGCGGGTGC

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARIAGIMAAKRTSELIPLCHPLA
IAGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAASVAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE

Sequences:

>Translated_158_residues
MSRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARIAGIMAAKRTSELIPLCHPLA
IAGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAASVAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE
>Mature_157_residues
SRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARIAGIMAAKRTSELIPLCHPLAI
AGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAASVAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=60.7594936708861, Blast_Score=186, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28574490, Length=158, Percent_Identity=49.3670886075949, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=49.3055555555556, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_ACICJ (A5FXW0)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234361.1
- ProteinModelPortal:   A5FXW0
- SMR:   A5FXW0
- STRING:   A5FXW0
- GeneID:   5161383
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1231
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- BioCyc:   ACRY349163:ACRY_1231-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16597; Mature: 16466

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARI
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHEEEEEECEEEEEEECCCCCCCCEEHHHHH
AGIMAAKRTSELIPLCHPLAIAGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAAS
HHHHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
VAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SRLTHIDERGAARMVDVSGKAETAREATAACHVTMRAETLALVTEGTAKKGDVLATARI
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHEEEEEECEEEEEEECCCCCCCCEEHHHHH
AGIMAAKRTSELIPLCHPLAIAGVTLELEPDAALPGIRIAATVKTTGPTGVEMEALTAAS
HHHHHHHHCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
VAALTVYDMLKAAEREMRIEGLRVIRKSGGKSGDFRQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA