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The map label for this gene is ctaA1

Identifier: 148260227

GI number: 148260227

Start: 1363067

End: 1364143

Strand: Reverse

Name: ctaA1

Synonym: Acry_1224

Alternate gene names: 148260227

Gene position: 1364143-1363067 (Counterclockwise)

Preceding gene: 148260228

Following gene: 148260226

Centisome position: 40.25

GC content: 69.08

Gene sequence:

>1077_bases
ATGAGCGGTGCGGCGGCGCGGGGGGACCGGCTGGTCGGCACCTGGCTGCTCGTCATCTGCTTCATGATCTTCGGCATGGT
GGTGGGCGGCGGCCATGCGCGGACGATCGGCGCGGGGTTCGTGATCCAGACCTGGCAGCCCTTCACCGGCATCGTCCCCC
CGCTGACCCATGCCGCCTGGGAGCGCGCCTTCGGCCTCTACAAGGCGACGGCGCAGTATCAGGCGATGCAGCCGAAGATG
ACGCTGGCGCAGTTCCAGTCGCTCTACCTGCCGATGTTCCTCGACCGCGACTGGGGGCGGCTGATGGCGGTGGTGTTCCT
GGTGCCGCTGGCGGTCTTCCGGCTGCGGGGGCGGATTTCGAACCGGCTGACCGCCTGGCTGCTGTTCCTGTTCGGGCTCG
GCGCCGGCGAGGCGACGATGGGCTGGTACATGACCTACGAGGGCATGACGAGCCGCATCCTCCAGCCCTCGCCGCTGTAT
CTCGGGCCGCATTTCGTGCTGGCGATGCTGATCTTCACCGCCATGCTGTGGACGGCGCTGACGCTGCGCAACCCCGAGCC
GGCGATTCTGCCGGGTCTTGCCCGGCTGCGCGGGCTGCTGAGCGTCTCGATCGGGCTGATCATCGCCACGATCGGGCTCG
GCGCGCTGGTGGCGGCGAGCGGGGCGCTCAAGGTGTACAACACGTTTCCGCTGATGGACGGGCACGCGCTGCCGCCGCAC
GCGCTGGCGATGCACCCGCTCTGGCTCAATTTCCTCGCCAACAAGGCGACGGTGCAGTTCGAGCACCGGGTGGCGGCGAC
GGTGACGGCGATCGTCGTCGTGATCGCCGCGGCGATGGGGCTGCGCGCGCCGGTGGGGGCGAAGGCGCGCGACCTGTTCC
TGCTCTTGGCCGGGCTGGTTTCGCTCCAATATATCCTGGGCATGAGCACGCTGGTCTCGGGCATGGCCGAACTCGGCTAT
GTGCACGAGCTGAACGCCGTGCTGCTGCTCGCCGCCTGCATCGCCTGCCGCCACGCGCTGCGCGGTGCGACGGCGGCGGT
GCCGCTTCCCGTCTATGAGATGAAGGCCGCTGAATGA

Upstream 100 bases:

>100_bases
TCTCCAAGATTCTCGATATCGGCATCGTGCACCAGCTCAACGCGGTGCTGCTGCTGGCCGCCGCGGTGTGGGCCTGGTTC
GAGCTGCGCGGGCGGCCGGC

Downstream 100 bases:

>100_bases
TGTCCGACACGATGCAAGACATGCTCGCCACCGCCGACCGGCTGTTCCACGGCAATGACGGGCTCGACGTGATCGAGGCG
CGGCGGGCCATCGCCCCCGT

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS 1; Cytochrome aa3-controlling protein 1

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAWERAFGLYKATAQYQAMQPKM
TLAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRISNRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLY
LGPHFVLAMLIFTAMLWTALTLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPH
ALAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLVSLQYILGMSTLVSGMAELGY
VHELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE

Sequences:

>Translated_358_residues
MSGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAWERAFGLYKATAQYQAMQPKM
TLAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRISNRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLY
LGPHFVLAMLIFTAMLWTALTLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPH
ALAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLVSLQYILGMSTLVSGMAELGY
VHELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE
>Mature_357_residues
SGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAWERAFGLYKATAQYQAMQPKMT
LAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRISNRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLYL
GPHFVLAMLIFTAMLWTALTLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPHA
LAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLVSLQYILGMSTLVSGMAELGYV
HELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=342, Percent_Identity=29.5321637426901, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI17921987, Length=324, Percent_Identity=30.5555555555556, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17536069, Length=346, Percent_Identity=29.7687861271676, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6320989, Length=375, Percent_Identity=27.7333333333333, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI19922860, Length=348, Percent_Identity=26.4367816091954, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA1_ACICJ (A5FXV3)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001234354.1
- STRING:   A5FXV3
- GeneID:   5159962
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1224
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   ADWESEF
- BioCyc:   ACRY349163:ACRY_1224-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 38614; Mature: 38483

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: BINDING 322-322

Signals:

None

Transmembrane regions:

HASH(0x14810100)-; HASH(0x13de0820)-; HASH(0x1493f538)-; HASH(0x140f5cf0)-; HASH(0x144c1ac0)-; HASH(0x13a7efbc)-; HASH(0x14a0f8d4)-; HASH(0x14bb195c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCHHHHHH
ERAFGLYKATAQYQAMQPKMTLAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLYLGPHFVLAMLIFTAMLWTAL
HHHHHHHHHHHHCCCCCCHHHHEEEECCHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHH
TLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPH
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH
ALAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLV
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLQYILGMSTLVSGMAELGYVHELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCH
>Mature Secondary Structure 
SGAAARGDRLVGTWLLVICFMIFGMVVGGGHARTIGAGFVIQTWQPFTGIVPPLTHAAW
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCHHHHHH
ERAFGLYKATAQYQAMQPKMTLAQFQSLYLPMFLDRDWGRLMAVVFLVPLAVFRLRGRIS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NRLTAWLLFLFGLGAGEATMGWYMTYEGMTSRILQPSPLYLGPHFVLAMLIFTAMLWTAL
HHHHHHHHHHHHCCCCCCHHHHEEEECCHHHHCCCCCCCEECHHHHHHHHHHHHHHHHHH
TLRNPEPAILPGLARLRGLLSVSIGLIIATIGLGALVAASGALKVYNTFPLMDGHALPPH
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH
ALAMHPLWLNFLANKATVQFEHRVAATVTAIVVVIAAAMGLRAPVGAKARDLFLLLAGLV
HHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLQYILGMSTLVSGMAELGYVHELNAVLLLAACIACRHALRGATAAVPLPVYEMKAAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA