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The map label for this gene is tldD [H]

Identifier: 148260226

GI number: 148260226

Start: 1361619

End: 1363070

Strand: Reverse

Name: tldD [H]

Synonym: Acry_1223

Alternate gene names: 148260226

Gene position: 1363070-1361619 (Counterclockwise)

Preceding gene: 148260227

Following gene: 148260222

Centisome position: 40.22

GC content: 71.63

Gene sequence:

>1452_bases
ATGATGTCCGACACGATGCAAGACATGCTCGCCACCGCCGACCGGCTGTTCCACGGCAATGACGGGCTCGACGTGATCGA
GGCGCGGCGGGCCATCGCCCCCGTGCTGGAGGCCGCCGACGATGGCGAGCTGTTCCTGGAATATCGCGAATCGGAGGTGG
TGAGCCTGGATGACGGGCGGATCCGCAACGCGAATTTCGACAGCCGGCGCGGCTTCGGCCTGCGCGCGGTGACCGGCGAG
GCGGCGGTCTATGCCCATGCCGGGGAGATTTCCGACGCGGCCCTGGCGCGCGCGGTGGAGACGCTGCGGGCGGCGCGGCA
GGGCGATGCCGGCACGGTGGCGGTCGCCCCCGCGGCGGCGACGCGCAGGCTCTATACCGGGCATAATCCGCTGGCGGAGA
TGCCCTTCGCGGCGCGGGCGGCGCTGCTCGGCGAGATCGACGCCTATGCCCGCGCCGCCGACAAGCGCGTGGTGCAGGTG
ATGGCGAGCCTGGCCGGCGAGTGGCAGGTGGTCGAGATCGTGCGGGCGGATGGGGTGCGCGTGGCCGATGTGCGGCCGCT
GGTGGTGCTGCACGTTTCCGTGGTGATGGAGCAGGACGGGCGGCGCGAATCGGGCGGCCACGGCGCCGGCGGGCGCGCGA
CCTATGACGGGGTGACGGCGCCGGCCTTCTGGCGGGCGGCGGTGGACGAATCGATCCGCAAGGCGGCGCTGAACCTCGAC
AGCGTGCCGGCGCCGGCGGGCGAGATGCCGGTGGTGCTGGGCGCGGGCTGGCCGGGCATTCTGCTCCACGAGGCGATCGG
CCATGGGCTGGAGGGCGATTTCAACCGCAAGAAGACCTCGGCCTTCGCCGGGCTGATGGGCAAGCGCGTCGGCTCGAAGG
GGGTCACCGTGGTCGATGACGGCACGATCCCCGACCGGCGCGGCTCGCTCAGCGTGGATGACGAGGGGACGCCGAGCGGG
CGCACCGTGCTGATCGAGGACGGCATCCTGACCGGCTACATGCAGGACCGGCAGAACGCGCGGCTGATGGGCATGGCGCC
GACGGGCAACGGGCGGCGGCAGTCCTACGCGCATCTGCCGATGCCGCGGATGACCAACACCATCATGCTGGAGGGCGAGG
CGAGCCGGGAGGACATGATCCGCTCGGTCAAGCGCGGCATCTATGCGGCGAATTTCGGCGGCGGGCAGGTGGACATCACC
TCGGGCAAGTTCGTGTTCACCGCCTCGGAGGCCTACATGATCGAGGACGGGCGGGTCGGCGCGCCGGTGAAGGGGGCGAC
GCTGATCGGCAACGGGCCGGACGCGCTGACCCGGGTGGAGATGATCGGCAACGACCTCGAACTCGACCCCGGCATCGGCA
CCTGCGGCAAGAACGGGCAGGGCGTGCCGGTGGGCGTGGGGCAGCCGAGCATCCTGATCGGCGGGCTGACCGTGGGCGGC
ACCGCCTCCTGA

Upstream 100 bases:

>100_bases
ACGCCGTGCTGCTGCTCGCCGCCTGCATCGCCTGCCGCCACGCGCTGCGCGGTGCGACGGCGGCGGTGCCGCTTCCCGTC
TATGAGATGAAGGCCGCTGA

Downstream 100 bases:

>100_bases
AACGGCAACCGCCGGCCCGGGGGACCGGACCGGCGGCTTCTGGCGTGGCGCGTTGCGCGGATCAGCGCGGCGCGAGCGCT
GCGACGCCCGGCAGGGTCTT

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MMSDTMQDMLATADRLFHGNDGLDVIEARRAIAPVLEAADDGELFLEYRESEVVSLDDGRIRNANFDSRRGFGLRAVTGE
AAVYAHAGEISDAALARAVETLRAARQGDAGTVAVAPAAATRRLYTGHNPLAEMPFAARAALLGEIDAYARAADKRVVQV
MASLAGEWQVVEIVRADGVRVADVRPLVVLHVSVVMEQDGRRESGGHGAGGRATYDGVTAPAFWRAAVDESIRKAALNLD
SVPAPAGEMPVVLGAGWPGILLHEAIGHGLEGDFNRKKTSAFAGLMGKRVGSKGVTVVDDGTIPDRRGSLSVDDEGTPSG
RTVLIEDGILTGYMQDRQNARLMGMAPTGNGRRQSYAHLPMPRMTNTIMLEGEASREDMIRSVKRGIYAANFGGGQVDIT
SGKFVFTASEAYMIEDGRVGAPVKGATLIGNGPDALTRVEMIGNDLELDPGIGTCGKNGQGVPVGVGQPSILIGGLTVGG
TAS

Sequences:

>Translated_483_residues
MMSDTMQDMLATADRLFHGNDGLDVIEARRAIAPVLEAADDGELFLEYRESEVVSLDDGRIRNANFDSRRGFGLRAVTGE
AAVYAHAGEISDAALARAVETLRAARQGDAGTVAVAPAAATRRLYTGHNPLAEMPFAARAALLGEIDAYARAADKRVVQV
MASLAGEWQVVEIVRADGVRVADVRPLVVLHVSVVMEQDGRRESGGHGAGGRATYDGVTAPAFWRAAVDESIRKAALNLD
SVPAPAGEMPVVLGAGWPGILLHEAIGHGLEGDFNRKKTSAFAGLMGKRVGSKGVTVVDDGTIPDRRGSLSVDDEGTPSG
RTVLIEDGILTGYMQDRQNARLMGMAPTGNGRRQSYAHLPMPRMTNTIMLEGEASREDMIRSVKRGIYAANFGGGQVDIT
SGKFVFTASEAYMIEDGRVGAPVKGATLIGNGPDALTRVEMIGNDLELDPGIGTCGKNGQGVPVGVGQPSILIGGLTVGG
TAS
>Mature_483_residues
MMSDTMQDMLATADRLFHGNDGLDVIEARRAIAPVLEAADDGELFLEYRESEVVSLDDGRIRNANFDSRRGFGLRAVTGE
AAVYAHAGEISDAALARAVETLRAARQGDAGTVAVAPAAATRRLYTGHNPLAEMPFAARAALLGEIDAYARAADKRVVQV
MASLAGEWQVVEIVRADGVRVADVRPLVVLHVSVVMEQDGRRESGGHGAGGRATYDGVTAPAFWRAAVDESIRKAALNLD
SVPAPAGEMPVVLGAGWPGILLHEAIGHGLEGDFNRKKTSAFAGLMGKRVGSKGVTVVDDGTIPDRRGSLSVDDEGTPSG
RTVLIEDGILTGYMQDRQNARLMGMAPTGNGRRQSYAHLPMPRMTNTIMLEGEASREDMIRSVKRGIYAANFGGGQVDIT
SGKFVFTASEAYMIEDGRVGAPVKGATLIGNGPDALTRVEMIGNDLELDPGIGTCGKNGQGVPVGVGQPSILIGGLTVGG
TAS

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=454, Percent_Identity=53.5242290748899, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI1790682, Length=448, Percent_Identity=23.8839285714286, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50688; Mature: 50688

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSDTMQDMLATADRLFHGNDGLDVIEARRAIAPVLEAADDGELFLEYRESEVVSLDDGR
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCE
IRNANFDSRRGFGLRAVTGEAAVYAHAGEISDAALARAVETLRAARQGDAGTVAVAPAAA
EECCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
TRRLYTGHNPLAEMPFAARAALLGEIDAYARAADKRVVQVMASLAGEWQVVEIVRADGVR
HHHEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEE
VADVRPLVVLHVSVVMEQDGRRESGGHGAGGRATYDGVTAPAFWRAAVDESIRKAALNLD
EECCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SVPAPAGEMPVVLGAGWPGILLHEAIGHGLEGDFNRKKTSAFAGLMGKRVGSKGVTVVDD
CCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
GTIPDRRGSLSVDDEGTPSGRTVLIEDGILTGYMQDRQNARLMGMAPTGNGRRQSYAHLP
CCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCC
MPRMTNTIMLEGEASREDMIRSVKRGIYAANFGGGQVDITSGKFVFTASEAYMIEDGRVG
CCCCCCEEEEECCCCHHHHHHHHHHCEEEEECCCCEEEEECCEEEEEECCEEEEECCCCC
APVKGATLIGNGPDALTRVEMIGNDLELDPGIGTCGKNGQGVPVGVGQPSILIGGLTVGG
CCCCCCEEECCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
TAS
CCC
>Mature Secondary Structure
MMSDTMQDMLATADRLFHGNDGLDVIEARRAIAPVLEAADDGELFLEYRESEVVSLDDGR
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCE
IRNANFDSRRGFGLRAVTGEAAVYAHAGEISDAALARAVETLRAARQGDAGTVAVAPAAA
EECCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCHH
TRRLYTGHNPLAEMPFAARAALLGEIDAYARAADKRVVQVMASLAGEWQVVEIVRADGVR
HHHEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEE
VADVRPLVVLHVSVVMEQDGRRESGGHGAGGRATYDGVTAPAFWRAAVDESIRKAALNLD
EECCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
SVPAPAGEMPVVLGAGWPGILLHEAIGHGLEGDFNRKKTSAFAGLMGKRVGSKGVTVVDD
CCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEC
GTIPDRRGSLSVDDEGTPSGRTVLIEDGILTGYMQDRQNARLMGMAPTGNGRRQSYAHLP
CCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCC
MPRMTNTIMLEGEASREDMIRSVKRGIYAANFGGGQVDITSGKFVFTASEAYMIEDGRVG
CCCCCCEEEEECCCCHHHHHHHHHHCEEEEECCCCEEEEECCEEEEEECCEEEEECCCCC
APVKGATLIGNGPDALTRVEMIGNDLELDPGIGTCGKNGQGVPVGVGQPSILIGGLTVGG
CCCCCCEEECCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
TAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]