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The map label for this gene is alsR [H]

Identifier: 148260160

GI number: 148260160

Start: 1288607

End: 1289527

Strand: Reverse

Name: alsR [H]

Synonym: Acry_1156

Alternate gene names: 148260160

Gene position: 1289527-1288607 (Counterclockwise)

Preceding gene: 148260169

Following gene: 148260159

Centisome position: 38.05

GC content: 72.2

Gene sequence:

>921_bases
ATGGATCGAACCGGCATGGAACTGCGGCATCTGCGCTATTTTGTCGCCGTCGCCGAGACGCTGAGTTTCACGGAAGCGGC
CCGCCGGCTCGCGATATCGCAGCCGCCGCTCAGCCAGCAGATCCGTGATCTCGAACTGGAAATCGGCACGACGCTGATCG
CCCGGTCGAGCCGGAACGTGTCGCTCACCCCCGCCGGCGCGGCCTTCCTGACCCGGGCGCGGCAGATCCTGGCGGAAGCC
GTCCGCGCGCGCGACGAGGCGCGGGTCATCGGCGCGGGCCGGTCGGGCACGCTGGATATCGGCATGACCGGCGCGGTCCT
GCTCGGCGGGCTCGGCGGCCTGGTGGCCGCGTTCCAGATATTCGCGCCGGGCGTGCAGGTGCGCCTGCACGAGATGCCAC
CCGGCGAGCAGGAGGCGGCGCTCGGCGCCGGGCGGCTCGATCTCTGCTTCCTGCGCACACCCGGCGCGGACCCGGCTCTC
CGTGTCGAGCCGGCCTGGCACGAAGGCGTCAGCGCGGTGCTTCCCCGCGATCATCCCCTGGCTGTCCGGCGCCGCCTCGC
CCTGGCTGACCTGCGCGACGAGCCCTTCGTGTTCTTCCGCCGCGCGGATTCGCGCTTCGCCGATCATCTCTGGACATGCT
GCATAGAGGCCGGCTTCGCCCCGCGCATCGTGCAGGAGGTGGTCGAGGCTCATGCCGTGATGGCGCTGGTTGCGGACGGG
TTCGGCATCGCGCTGCTGCCCGACTCCGCCCGCCGCCTCGCGCCGTCCGGTCTCGGCTTCCGCCCGCTCGCCGGCAATCC
GGCGCGGGCCGATGTCAGCCTCGTCTACCCGCGGGAGCATTCCGCCGTGGTCGGCGAGTTTATCGGCTTCGCCCGGACCC
GGCTCGGGCGCGGCGCGGGCAGCGGCGGACCGGGATCATAA

Upstream 100 bases:

>100_bases
TGCCGGACCGGCGCGACTGCGGCCGACCGCCTGATCGAAACTTGCCGAAGGGAGGCAATACGTCCAATATATTGTTCAGA
ATGATTGATATTTATTTCAT

Downstream 100 bases:

>100_bases
GCGCGCGCTTATATGTGTCATTTAAACTGCGACCCGCCCGTGCGATGGATTAGTCTGTTTCGTCGGAGTTGAAACGGGAC
GGGCCGCAAGGACCATGACA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDRTGMELRHLRYFVAVAETLSFTEAARRLAISQPPLSQQIRDLELEIGTTLIARSSRNVSLTPAGAAFLTRARQILAEA
VRARDEARVIGAGRSGTLDIGMTGAVLLGGLGGLVAAFQIFAPGVQVRLHEMPPGEQEAALGAGRLDLCFLRTPGADPAL
RVEPAWHEGVSAVLPRDHPLAVRRRLALADLRDEPFVFFRRADSRFADHLWTCCIEAGFAPRIVQEVVEAHAVMALVADG
FGIALLPDSARRLAPSGLGFRPLAGNPARADVSLVYPREHSAVVGEFIGFARTRLGRGAGSGGPGS

Sequences:

>Translated_306_residues
MDRTGMELRHLRYFVAVAETLSFTEAARRLAISQPPLSQQIRDLELEIGTTLIARSSRNVSLTPAGAAFLTRARQILAEA
VRARDEARVIGAGRSGTLDIGMTGAVLLGGLGGLVAAFQIFAPGVQVRLHEMPPGEQEAALGAGRLDLCFLRTPGADPAL
RVEPAWHEGVSAVLPRDHPLAVRRRLALADLRDEPFVFFRRADSRFADHLWTCCIEAGFAPRIVQEVVEAHAVMALVADG
FGIALLPDSARRLAPSGLGFRPLAGNPARADVSLVYPREHSAVVGEFIGFARTRLGRGAGSGGPGS
>Mature_306_residues
MDRTGMELRHLRYFVAVAETLSFTEAARRLAISQPPLSQQIRDLELEIGTTLIARSSRNVSLTPAGAAFLTRARQILAEA
VRARDEARVIGAGRSGTLDIGMTGAVLLGGLGGLVAAFQIFAPGVQVRLHEMPPGEQEAALGAGRLDLCFLRTPGADPAL
RVEPAWHEGVSAVLPRDHPLAVRRRLALADLRDEPFVFFRRADSRFADHLWTCCIEAGFAPRIVQEVVEAHAVMALVADG
FGIALLPDSARRLAPSGLGFRPLAGNPARADVSLVYPREHSAVVGEFIGFARTRLGRGAGSGGPGS

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=279, Percent_Identity=40.5017921146953, Blast_Score=180, Evalue=9e-47,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=35.016835016835, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI2367136, Length=271, Percent_Identity=36.1623616236162, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI157672245, Length=301, Percent_Identity=31.5614617940199, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=31.6363636363636, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=29.3650793650794, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=27.6679841897233, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788296, Length=242, Percent_Identity=29.7520661157025, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790262, Length=243, Percent_Identity=27.5720164609054, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789204, Length=293, Percent_Identity=30.7167235494881, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=27.4590163934426, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=277, Percent_Identity=25.6317689530686, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=33.6065573770492, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789506, Length=231, Percent_Identity=24.6753246753247, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789173, Length=173, Percent_Identity=30.635838150289, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32677; Mature: 32677

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTGMELRHLRYFVAVAETLSFTEAARRLAISQPPLSQQIRDLELEIGTTLIARSSRNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCE
SLTPAGAAFLTRARQILAEAVRARDEARVIGAGRSGTLDIGMTGAVLLGGLGGLVAAFQI
EECCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHH
FAPGVQVRLHEMPPGEQEAALGAGRLDLCFLRTPGADPALRVEPAWHEGVSAVLPRDHPL
HCCCCEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCCCEEECCCHHCCCHHHCCCCCCH
AVRRRLALADLRDEPFVFFRRADSRFADHLWTCCIEAGFAPRIVQEVVEAHAVMALVADG
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
FGIALLPDSARRLAPSGLGFRPLAGNPARADVSLVYPREHSAVVGEFIGFARTRLGRGAG
CCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
SGGPGS
CCCCCC
>Mature Secondary Structure
MDRTGMELRHLRYFVAVAETLSFTEAARRLAISQPPLSQQIRDLELEIGTTLIARSSRNV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCCCE
SLTPAGAAFLTRARQILAEAVRARDEARVIGAGRSGTLDIGMTGAVLLGGLGGLVAAFQI
EECCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHH
FAPGVQVRLHEMPPGEQEAALGAGRLDLCFLRTPGADPALRVEPAWHEGVSAVLPRDHPL
HCCCCEEEEECCCCCHHHHHCCCCCEEEEEEECCCCCCCEEECCCHHCCCHHHCCCCCCH
AVRRRLALADLRDEPFVFFRRADSRFADHLWTCCIEAGFAPRIVQEVVEAHAVMALVADG
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
FGIALLPDSARRLAPSGLGFRPLAGNPARADVSLVYPREHSAVVGEFIGFARTRLGRGAG
CCEEECCCCHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCC
SGGPGS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]