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The map label for this gene is nuoH1 [H]

Identifier: 148260118

GI number: 148260118

Start: 1239931

End: 1240902

Strand: Reverse

Name: nuoH1 [H]

Synonym: Acry_1114

Alternate gene names: 148260118

Gene position: 1240902-1239931 (Counterclockwise)

Preceding gene: 148260119

Following gene: 148260117

Centisome position: 36.61

GC content: 65.02

Gene sequence:

>972_bases
ATGACCCACGGCAACGAGATCGTCATCGGCCTGCTGAACGTCGTGATCGGCCTCGCGGTGCTGATGGCGGCCGCCGCGCT
GCTGACCTGGATCGAACGCCGCCTGCTCGGGTTCTGGCAGGACCGTTACGGCCCCAACCGCGCCGGCCCCTTCGGCGTGC
TCCAGGTCGTCGCCGACGGCATCAAGCTGCTCTTCAAGCAGGACTGGATTCCCCCCTTCGCCGACCCGGTCATCTTCGTC
CTCGCCCCGGCCATCTCGATGGTCACGGTGATGCTCGCCATCGCGGTCGTCCCGGCGACGCCGATGATCGGCATCATCGG
CAATCTCAATGTCGGCCTGCTGTTCTTCCTCGCCATGAGCGGGCTCGGCGTCTACTCGGTGGTGCTCGCCGGCTGGTCGT
CGAACAACAAGTTCTCGCTCCTCGGCGGCATGCGCGCCGCCGCCCAGATGGTCAGCTACGAGGTCTTCATGGGGCTGTCG
CTGGTGGGCGTGGTGATGCTCGCCGGCTCCTTCAACCTCACCGATGTCGTGCACAGCCAGCGGCATCTCTGGTACGTGGT
GCCGCAATTCATCGGCTTCGTCGTCTTCTTCCTCGGCGGCATCGCGGAAACCCACCGCCTCCCGTTCGACCTGCCCGAAG
GCGAGAACGAACTCGGCGCCGGGTTCCACACCGAATATTCCGGCATGAAGTTCGGCATGTTCTTCGTCGGCGAATATATC
GGCATCATCGTCGTCTCGGCGATGACGACGGTGCTGTTCCTCGGCGGCTGGTATGGCCCGCTGCTGCCGCCCTTCCTCTG
GTTCGCGATCAAGACCGGGTTTTTCGTCGCCTTCTTCATCCTGCTGCGCGCCGCCCTGCCGCGCCCGCGCTACGACCAGT
TCATGGCGTTCGGCTGGAAGATCCTGCTGCCGCTCACCTTGCTGAACATTCTCGTCACCGGCGCGCTCATGCTCGCCGGG
CCGGCCATATGA

Upstream 100 bases:

>100_bases
CCGCCCTGCCGCGCGGCGTCGCCGGGCTCGCCGGCTTCGCGCAGAGGCCGCACGCCATCCCCGCATGGCTGCGGCTGCGC
CCGGCGGAGCCGCCCGTGTC

Downstream 100 bases:

>100_bases
AGGGGAGGGGATCATGCTGAGTTCGCTGGTCACGCTCTGGTACACGTTCCTCCACCTGTTCCAGCGCAACGTGACGGTAT
CCTATCCCGACGAGATGCCC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MTHGNEIVIGLLNVVIGLAVLMAAAALLTWIERRLLGFWQDRYGPNRAGPFGVLQVVADGIKLLFKQDWIPPFADPVIFV
LAPAISMVTVMLAIAVVPATPMIGIIGNLNVGLLFFLAMSGLGVYSVVLAGWSSNNKFSLLGGMRAAAQMVSYEVFMGLS
LVGVVMLAGSFNLTDVVHSQRHLWYVVPQFIGFVVFFLGGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFVGEYI
GIIVVSAMTTVLFLGGWYGPLLPPFLWFAIKTGFFVAFFILLRAALPRPRYDQFMAFGWKILLPLTLLNILVTGALMLAG
PAI

Sequences:

>Translated_323_residues
MTHGNEIVIGLLNVVIGLAVLMAAAALLTWIERRLLGFWQDRYGPNRAGPFGVLQVVADGIKLLFKQDWIPPFADPVIFV
LAPAISMVTVMLAIAVVPATPMIGIIGNLNVGLLFFLAMSGLGVYSVVLAGWSSNNKFSLLGGMRAAAQMVSYEVFMGLS
LVGVVMLAGSFNLTDVVHSQRHLWYVVPQFIGFVVFFLGGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFVGEYI
GIIVVSAMTTVLFLGGWYGPLLPPFLWFAIKTGFFVAFFILLRAALPRPRYDQFMAFGWKILLPLTLLNILVTGALMLAG
PAI
>Mature_322_residues
THGNEIVIGLLNVVIGLAVLMAAAALLTWIERRLLGFWQDRYGPNRAGPFGVLQVVADGIKLLFKQDWIPPFADPVIFVL
APAISMVTVMLAIAVVPATPMIGIIGNLNVGLLFFLAMSGLGVYSVVLAGWSSNNKFSLLGGMRAAAQMVSYEVFMGLSL
VGVVMLAGSFNLTDVVHSQRHLWYVVPQFIGFVVFFLGGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFVGEYIG
IIVVSAMTTVLFLGGWYGPLLPPFLWFAIKTGFFVAFFILLRAALPRPRYDQFMAFGWKILLPLTLLNILVTGALMLAGP
AI

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=286, Percent_Identity=41.958041958042, Blast_Score=224, Evalue=6e-59,
Organism=Escherichia coli, GI1788618, Length=313, Percent_Identity=61.6613418530351, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789077, Length=237, Percent_Identity=32.4894514767932, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 35183; Mature: 35051

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHGNEIVIGLLNVVIGLAVLMAAAALLTWIERRLLGFWQDRYGPNRAGPFGVLQVVADG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IKLLFKQDWIPPFADPVIFVLAPAISMVTVMLAIAVVPATPMIGIIGNLNVGLLFFLAMS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
GLGVYSVVLAGWSSNNKFSLLGGMRAAAQMVSYEVFMGLSLVGVVMLAGSFNLTDVVHSQ
CCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
RHLWYVVPQFIGFVVFFLGGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFVGEYI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GIIVVSAMTTVLFLGGWYGPLLPPFLWFAIKTGFFVAFFILLRAALPRPRYDQFMAFGWK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILLPLTLLNILVTGALMLAGPAI
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
THGNEIVIGLLNVVIGLAVLMAAAALLTWIERRLLGFWQDRYGPNRAGPFGVLQVVADG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
IKLLFKQDWIPPFADPVIFVLAPAISMVTVMLAIAVVPATPMIGIIGNLNVGLLFFLAMS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
GLGVYSVVLAGWSSNNKFSLLGGMRAAAQMVSYEVFMGLSLVGVVMLAGSFNLTDVVHSQ
CCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
RHLWYVVPQFIGFVVFFLGGIAETHRLPFDLPEGENELGAGFHTEYSGMKFGMFFVGEYI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GIIVVSAMTTVLFLGGWYGPLLPPFLWFAIKTGFFVAFFILLRAALPRPRYDQFMAFGWK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ILLPLTLLNILVTGALMLAGPAI
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA