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The map label for this gene is bah [H]

Identifier: 148260093

GI number: 148260093

Start: 1210422

End: 1211339

Strand: Reverse

Name: bah [H]

Synonym: Acry_1086

Alternate gene names: 148260093

Gene position: 1211339-1210422 (Counterclockwise)

Preceding gene: 148260094

Following gene: 148260091

Centisome position: 35.74

GC content: 73.75

Gene sequence:

>918_bases
ATGCCGAGCCTCGCCTCCCACATCGTCAACCCGCTCATCCGCGCGGTCGTCAAGTCGCAGCTCTCCGCCGACGTCTCCGG
CCGCACCGAGGCGGCCATCGCCCGCCGCGTCCGCCGCGCCCTCGGCACCCCGGTCCTGCCGCCGCCCGGCGGTCGCTACG
TGAAGGGCGAGTGCGGCGGCATCCCCGGATTGTGGACCGAGCCGAAGGCGCCGCCCGCCGCCACCGTGCTCTACATCCAT
GGCGGCGGCTTCATCGCCTGCTCGCCGGCCACGCACAAACCCTTCACCCTCGCCTTCGCGAAGCGCGGCTTCCGCGTCTT
CGCGCCGGACTACCGCCTCGCGCCGGAACACCGCTTTCCCGCGGCGCTCGACGATGCGCTCGCCGCCTATCGCGGCCTGC
TCGATGCGGGGGGCGATCCGGCCTCGCTCGTCATCGCCGGCGATTCCGCGGGCGGCGGCCTCGCCCTGTCCACCCTGGTC
GCGGCGAAGCGCGACGGCCTGCCGATGCCCGCCTGCGCCGTGCTGTTCTCGCCCTGGACCGATCTTGCCTGCGCCGGCGA
CAGCATGCGGACCAACCTGCGCGCCGACCCGATGCTCTGCGCCACCACCATGCCCGCCGCCGCCGCGCTCTATCTCGGCG
CCGCCGACGAGCGCGATCCGCTCGCCTCGCCGCTGCACGCCGACCTCGCCGGCCTGCCGCCGCTCTGCATCCACGCCAGC
GCGATCGAGGTGCTGCGCGACGACAGCACCCGCCTCGCCACCAGGGCGCGCGAGGCCGGCGTCGAGGTCAGCATCCGGCT
GTGGGACAACATGCCCCATGTCTGGCCGATCTTTCAGCTCCTGCTGCCCGAGGCGCGGCGGACGATGGACGAGGTCGCCG
AATACCTCACCGCCCGCATCGCCCAAACGCGCCGTTAG

Upstream 100 bases:

>100_bases
TCCCGGTCGGCCACGCGAAACTCGTCGCCCGCCAGGCCAGCGGGATGCCCTCGTCCCTCGCCGCCCAACTCACCCGCGCC
CGGCCCTGAAGGGAAACGCC

Downstream 100 bases:

>100_bases
TTGCCGCCGGGCGGCGCGGGCTCAGAATTCCTCCGTCAGCTCGACATAGAGCTGGTTGCGGCGGAAGTTGAAGATGCTGT
CGCTGGAAATCCGCTGCGTG

Product: alpha/beta hydrolase domain-containing protein

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPSLASHIVNPLIRAVVKSQLSADVSGRTEAAIARRVRRALGTPVLPPPGGRYVKGECGGIPGLWTEPKAPPAATVLYIH
GGGFIACSPATHKPFTLAFAKRGFRVFAPDYRLAPEHRFPAALDDALAAYRGLLDAGGDPASLVIAGDSAGGGLALSTLV
AAKRDGLPMPACAVLFSPWTDLACAGDSMRTNLRADPMLCATTMPAAAALYLGAADERDPLASPLHADLAGLPPLCIHAS
AIEVLRDDSTRLATRAREAGVEVSIRLWDNMPHVWPIFQLLLPEARRTMDEVAEYLTARIAQTRR

Sequences:

>Translated_305_residues
MPSLASHIVNPLIRAVVKSQLSADVSGRTEAAIARRVRRALGTPVLPPPGGRYVKGECGGIPGLWTEPKAPPAATVLYIH
GGGFIACSPATHKPFTLAFAKRGFRVFAPDYRLAPEHRFPAALDDALAAYRGLLDAGGDPASLVIAGDSAGGGLALSTLV
AAKRDGLPMPACAVLFSPWTDLACAGDSMRTNLRADPMLCATTMPAAAALYLGAADERDPLASPLHADLAGLPPLCIHAS
AIEVLRDDSTRLATRAREAGVEVSIRLWDNMPHVWPIFQLLLPEARRTMDEVAEYLTARIAQTRR
>Mature_304_residues
PSLASHIVNPLIRAVVKSQLSADVSGRTEAAIARRVRRALGTPVLPPPGGRYVKGECGGIPGLWTEPKAPPAATVLYIHG
GGFIACSPATHKPFTLAFAKRGFRVFAPDYRLAPEHRFPAALDDALAAYRGLLDAGGDPASLVIAGDSAGGGLALSTLVA
AKRDGLPMPACAVLFSPWTDLACAGDSMRTNLRADPMLCATTMPAAAALYLGAADERDPLASPLHADLAGLPPLCIHASA
IEVLRDDSTRLATRAREAGVEVSIRLWDNMPHVWPIFQLLLPEARRTMDEVAEYLTARIAQTRR

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=163, Percent_Identity=31.9018404907975, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786682, Length=244, Percent_Identity=26.6393442622951, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32291; Mature: 32159

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01173 LIPASE_GDXG_HIS ; PS01174 LIPASE_GDXG_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLASHIVNPLIRAVVKSQLSADVSGRTEAAIARRVRRALGTPVLPPPGGRYVKGECGG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCC
IPGLWTEPKAPPAATVLYIHGGGFIACSPATHKPFTLAFAKRGFRVFAPDYRLAPEHRFP
CCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEHHCCCEEECCCCCCCCCCCCC
AALDDALAAYRGLLDAGGDPASLVIAGDSAGGGLALSTLVAAKRDGLPMPACAVLFSPWT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCH
DLACAGDSMRTNLRADPMLCATTMPAAAALYLGAADERDPLASPLHADLAGLPPLCIHAS
HHHCCCCHHHCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
AIEVLRDDSTRLATRAREAGVEVSIRLWDNMPHVWPIFQLLLPEARRTMDEVAEYLTARI
HHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTRR
HHCCC
>Mature Secondary Structure 
PSLASHIVNPLIRAVVKSQLSADVSGRTEAAIARRVRRALGTPVLPPPGGRYVKGECGG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCC
IPGLWTEPKAPPAATVLYIHGGGFIACSPATHKPFTLAFAKRGFRVFAPDYRLAPEHRFP
CCCCCCCCCCCCCEEEEEEECCCEEEECCCCCCCEEEEEHHCCCEEECCCCCCCCCCCCC
AALDDALAAYRGLLDAGGDPASLVIAGDSAGGGLALSTLVAAKRDGLPMPACAVLFSPWT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCH
DLACAGDSMRTNLRADPMLCATTMPAAAALYLGAADERDPLASPLHADLAGLPPLCIHAS
HHHCCCCHHHCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
AIEVLRDDSTRLATRAREAGVEVSIRLWDNMPHVWPIFQLLLPEARRTMDEVAEYLTARI
HHHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQTRR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]