BacMap

Definition	Acidiphilium cryptum JF-5 chromosome, complete genome.
Accession	NC_009484
Length	3,389,227

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The map label for this gene is ucpA [C]

Identifier: 148260094

GI number: 148260094

Start: 1211351

End: 1212211

Strand: Reverse

Name: ucpA [C]

Synonym: Acry_1087

Alternate gene names: 148260094

Gene position: 1212211-1211351 (Counterclockwise)

Preceding gene: 148260095

Following gene: 148260093

Centisome position: 35.77

GC content: 72.82

Gene sequence:

>861_bases
ATGAAACTGAACCTCGACGGCGCCGTCGCCGTCATCACGGGCGCCGCCAGCGGCATGGGCGCCGAGCTCGCCGTGCGGAT
GGCGGCGAAAGGCAGTCGCCTCGCCCTGGTCGATCGCGACGCGGCCGGGCTCGACGGCGTCAGCCGCCGCATCGCCGCCC
TGCATCGCGCGCCGCTCACCACCCATGTCGCCGACCTTGCCGACCGCGCCGCCATCGCCGCGCTGCCCGATGCAGTGCTC
GCCGCCCACGGCAAGGTCACGGTGCTGGTCAGCAATGCCGGCGTCGCCCTGGCCGGCCCGTTCGACGATTACGGTCCGGA
CGATTTCGAGTGGCTGATGGACATCAACTTCTGGGCCGGCATCCGCCTGACCACCGCCTTCCTGCCGCATCTCAAGCGCG
CGCCGGCGGCGCAGATCGCCTATACCTCGTCGGTCTTCGGCATCGTCGGCGTGCCCGGCAACGTCGCCTATTGCGCCAGC
AAGTTCGCGATCCGCGGCTTCGCCGAGGCGGTGCGCCAGGAACTCGCCGGCACCAGCGTCGGCATCACCGTCATCCATCC
GGGCGGGGTGAACACCGCCATCGCCCGCAGCGCCCGCGTCGCCCGCGGCACCGATGCCGCCGCGGCGGCGGAGGGCCTCG
TGCAGTTCGAGAAACTCCTCCGCACCCCGGCCGACAAGGCCGCCGCCGCGATCCTCGATGGCATCGAGCGCCGCCGCAAC
CGCGTGCTGATCGGCGCCGACGCCCGCGTGCTGGACTGGATCCAGCGCCTCCTCCCGGTCGGCCACGCGAAACTCGTCGC
CCGCCAGGCCAGCGGGATGCCCTCGTCCCTCGCCGCCCAACTCACCCGCGCCCGGCCCTGA

Upstream 100 bases:

>100_bases
CTGGCCCGGCACCGTCGTCGGCTACCGCCGCGCGACCGCCGCGGCCGACCTCGCCGACTACCAAACGAGCCGTTAGGCAA
CTGCACGTGAGAACACGCCG

Downstream 100 bases:

>100_bases
AGGGAAACGCCATGCCGAGCCTCGCCTCCCACATCGTCAACCCGCTCATCCGCGCGGTCGTCAAGTCGCAGCTCTCCGCC
GACGTCTCCGGCCGCACCGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKLNLDGAVAVITGAASGMGAELAVRMAAKGSRLALVDRDAAGLDGVSRRIAALHRAPLTTHVADLADRAAIAALPDAVL
AAHGKVTVLVSNAGVALAGPFDDYGPDDFEWLMDINFWAGIRLTTAFLPHLKRAPAAQIAYTSSVFGIVGVPGNVAYCAS
KFAIRGFAEAVRQELAGTSVGITVIHPGGVNTAIARSARVARGTDAAAAAEGLVQFEKLLRTPADKAAAAILDGIERRRN
RVLIGADARVLDWIQRLLPVGHAKLVARQASGMPSSLAAQLTRARP

Sequences:

>Translated_286_residues
MKLNLDGAVAVITGAASGMGAELAVRMAAKGSRLALVDRDAAGLDGVSRRIAALHRAPLTTHVADLADRAAIAALPDAVL
AAHGKVTVLVSNAGVALAGPFDDYGPDDFEWLMDINFWAGIRLTTAFLPHLKRAPAAQIAYTSSVFGIVGVPGNVAYCAS
KFAIRGFAEAVRQELAGTSVGITVIHPGGVNTAIARSARVARGTDAAAAAEGLVQFEKLLRTPADKAAAAILDGIERRRN
RVLIGADARVLDWIQRLLPVGHAKLVARQASGMPSSLAAQLTRARP
>Mature_286_residues
MKLNLDGAVAVITGAASGMGAELAVRMAAKGSRLALVDRDAAGLDGVSRRIAALHRAPLTTHVADLADRAAIAALPDAVL
AAHGKVTVLVSNAGVALAGPFDDYGPDDFEWLMDINFWAGIRLTTAFLPHLKRAPAAQIAYTSSVFGIVGVPGNVAYCAS
KFAIRGFAEAVRQELAGTSVGITVIHPGGVNTAIARSARVARGTDAAAAAEGLVQFEKLLRTPADKAAAAILDGIERRRN
RVLIGADARVLDWIQRLLPVGHAKLVARQASGMPSSLAAQLTRARP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=208, Percent_Identity=34.6153846153846, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=34.1584158415842, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=36.6492146596859, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI142976729, Length=261, Percent_Identity=28.735632183908, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI4503817, Length=195, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=32.972972972973, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=31.9587628865979, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI310128830, Length=208, Percent_Identity=31.7307692307692, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI310115468, Length=208, Percent_Identity=31.7307692307692, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI157739938, Length=247, Percent_Identity=27.9352226720648, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI210032110, Length=258, Percent_Identity=24.4186046511628, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI25282469, Length=227, Percent_Identity=26.8722466960352, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI166795268, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=26.063829787234, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=26.063829787234, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=26.063829787234, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI150247226, Length=204, Percent_Identity=30.3921568627451, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI186928839, Length=210, Percent_Identity=30, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=31.8627450980392, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38424085, Length=232, Percent_Identity=31.8965517241379, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI32483357, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI38348362, Length=182, Percent_Identity=32.4175824175824, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082100, Length=224, Percent_Identity=33.0357142857143, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786701, Length=189, Percent_Identity=30.6878306878307, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787335, Length=195, Percent_Identity=24.6153846153846, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787820, Length=202, Percent_Identity=28.2178217821782, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1786812, Length=199, Percent_Identity=26.1306532663317, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082160, Length=199, Percent_Identity=24.6231155778894, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=144, Percent_Identity=29.1666666666667, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=192, Percent_Identity=30.7291666666667, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=210, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71997402, Length=265, Percent_Identity=27.1698113207547, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17570069, Length=202, Percent_Identity=29.7029702970297, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=30.8900523560209, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=187, Percent_Identity=28.8770053475936, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=173, Percent_Identity=26.0115606936416, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=199, Percent_Identity=26.1306532663317, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=221, Percent_Identity=27.6018099547511, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=192, Percent_Identity=26.5625, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=223, Percent_Identity=26.9058295964126, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=192, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=270, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=26.2626262626263, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21358495, Length=271, Percent_Identity=28.0442804428044, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281364892, Length=201, Percent_Identity=29.8507462686567, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640492, Length=235, Percent_Identity=26.3829787234043, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=33.5106382978723, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=32.7956989247312, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=33.5106382978723, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356301, Length=186, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355631, Length=257, Percent_Identity=24.5136186770428, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=26.4550264550265, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=32.6424870466321, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571387, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553409, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647948, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647946, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24581726, Length=199, Percent_Identity=26.6331658291457, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221510726, Length=189, Percent_Identity=31.7460317460317, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573296, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=198, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641232, Length=239, Percent_Identity=28.0334728033473, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24584744, Length=200, Percent_Identity=28, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=195, Percent_Identity=28.7179487179487, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574402, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29644; Mature: 29644

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNLDGAVAVITGAASGMGAELAVRMAAKGSRLALVDRDAAGLDGVSRRIAALHRAPLT
CEECCCCCEEEEEECCCCCCHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHH
THVADLADRAAIAALPDAVLAAHGKVTVLVSNAGVALAGPFDDYGPDDFEWLMDINFWAG
HHHHHHHHHHHHHHCCHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCHHEEEECCHHCC
IRLTTAFLPHLKRAPAAQIAYTSSVFGIVGVPGNVAYCASKFAIRGFAEAVRQELAGTSV
HHHHHHHHHHHHCCCCHHHEEHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GITVIHPGGVNTAIARSARVARGTDAAAAAEGLVQFEKLLRTPADKAAAAILDGIERRRN
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
RVLIGADARVLDWIQRLLPVGHAKLVARQASGMPSSLAAQLTRARP
EEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLNLDGAVAVITGAASGMGAELAVRMAAKGSRLALVDRDAAGLDGVSRRIAALHRAPLT
CEECCCCCEEEEEECCCCCCHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCHH
THVADLADRAAIAALPDAVLAAHGKVTVLVSNAGVALAGPFDDYGPDDFEWLMDINFWAG
HHHHHHHHHHHHHHCCHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCHHEEEECCHHCC
IRLTTAFLPHLKRAPAAQIAYTSSVFGIVGVPGNVAYCASKFAIRGFAEAVRQELAGTSV
HHHHHHHHHHHHCCCCHHHEEHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GITVIHPGGVNTAIARSARVARGTDAAAAAEGLVQFEKLLRTPADKAAAAILDGIERRRN
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
RVLIGADARVLDWIQRLLPVGHAKLVARQASGMPSSLAAQLTRARP
EEEEECCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA