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The map label for this gene is carA [H]

Identifier: 148259923

GI number: 148259923

Start: 1008143

End: 1009486

Strand: Reverse

Name: carA [H]

Synonym: Acry_0912

Alternate gene names: 148259923

Gene position: 1009486-1008143 (Counterclockwise)

Preceding gene: 148259955

Following gene: 148259922

Centisome position: 29.79

GC content: 68.53

Gene sequence:

>1344_bases
ATGCCCAAGACGACAGACGAGATCATCGACCTGCTGGGCGGCGCCGACGCGGCAGCCCGGCTGACCCAGGTTTCGACCGA
GGCCGTGCGCAAGTGGCGCAGCGCCGGGGCGATTCCGGCACGGCACTGGCCGGCGGTGATTGCCGCGACCGGCCTGTCCC
TGGCCGATCTTTCAGGAGACATTGCAATGGAATCCGAAACCACGAAACCGGAGGGCGCAACCGCGGCGCTGGTATTGGGC
GACGGCCGCGTGTTCTGGGGACGCGGCTTCGGCGCGCATTCCACCGGCGAGCCGGCGGAACTCTGCTTCTCCACCGGCAT
GACCGGCTATCAGGAAACCCTGACCGATCCGTCCTTCGCCGGGCAGATCATCACCTTCACCTTCCCGCATATCGGCAATG
TCGGCGCCAATCCCGAGGATATCGAGGCGAACACGAGTTTCGCCCGCGGCCTCGTGATCAACCGCGACATCACCCGTCCG
TCGAACTGGCGCGCCGCCGAGGGGCTGGCCGCCTGGTGCCGCCGCATGGGCCTGCCGGGCATCGCCGGAGTCGACACCCG
CGCCCTCACCCGCACCATCCGCGACGACGGCCCGCCCAACGCGCTGATCGCCTATCCCGAGGACGGCCGCTTCGACATCC
CCGCCCTGGTCGAGCGGGCCCGCGCCTGGCCGGGGCTCGAGGGCATGGACCTCGCGCGCGAGGTCTCCTGCACCCAGAGC
TACGAATGGACCGAGACGCTGTGGGACCGCGCGCACGGGTTCGGCCGGCAGAACGCGCCGAAATTTACTGTAGTTGCCGT
GGATTACGGCGCGAAGCGCAACATCCTTCGCAACCTCGCGAGCGCCGGCTGCCGGGTCATCGTCGTCCCCGCCACCGCCT
CGGCCGAGGATATCCTCCGTCATCAGCCTGATGGCGTGTTCCTCTCCAACGGCCCCGGCGACCCTGCGGCGACGGCCGAA
TACGCCGTGCCGGCGATCCGCGGCGTGCTCGATGCCGGCAAGCCGCTCTTCGGCATCTGCCTCGGCCACCAGCTCCTCGC
CCACACGCTTGGCGCGAAGACCTACAAGCTCGCCCGCGGCCATCGCGGCGCCAACCAGCCGGTGCAGGAGCTTGCCACCG
GCAAGGTCGAGATCACCAGCCAGAATCATGGCTTCGCGGTGGATGAGGCCAGCCTGCCCGACGGCGTGACGGTCACCCAT
CGCTCCCTGTTCGATGGTTCGAACGAGGGCATCGCCTGCCCGGCGAAGAACTGCTTCTCCGTGCAATATCACCCCGAGGC
CAGCCCTGGCCCGTCGGATGCCAATCACCTGTTCCGGCGCTTTGTCGCGATGATGGAGGGCTGA

Upstream 100 bases:

>100_bases
AGAGCGCGGCAAAATGTCGTTGGCGGAAATAATTTCCGACCGCCCTCCGATCAGGAGAAGTCCGGTTGAATTCGGAGAAA
AAATCCGGCATGAGACCGTC

Downstream 100 bases:

>100_bases
CCATGCCGAAACGCACAGACATCAAATCGATCCTGATCATCGGCGCCGGGCCCATCGTCATCGGCCAGGCCTGCGAGTTC
GACTATTCCGGTGCCCAGGC

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPKTTDEIIDLLGGADAAARLTQVSTEAVRKWRSAGAIPARHWPAVIAATGLSLADLSGDIAMESETTKPEGATAALVLG
DGRVFWGRGFGAHSTGEPAELCFSTGMTGYQETLTDPSFAGQIITFTFPHIGNVGANPEDIEANTSFARGLVINRDITRP
SNWRAAEGLAAWCRRMGLPGIAGVDTRALTRTIRDDGPPNALIAYPEDGRFDIPALVERARAWPGLEGMDLAREVSCTQS
YEWTETLWDRAHGFGRQNAPKFTVVAVDYGAKRNILRNLASAGCRVIVVPATASAEDILRHQPDGVFLSNGPGDPAATAE
YAVPAIRGVLDAGKPLFGICLGHQLLAHTLGAKTYKLARGHRGANQPVQELATGKVEITSQNHGFAVDEASLPDGVTVTH
RSLFDGSNEGIACPAKNCFSVQYHPEASPGPSDANHLFRRFVAMMEG

Sequences:

>Translated_447_residues
MPKTTDEIIDLLGGADAAARLTQVSTEAVRKWRSAGAIPARHWPAVIAATGLSLADLSGDIAMESETTKPEGATAALVLG
DGRVFWGRGFGAHSTGEPAELCFSTGMTGYQETLTDPSFAGQIITFTFPHIGNVGANPEDIEANTSFARGLVINRDITRP
SNWRAAEGLAAWCRRMGLPGIAGVDTRALTRTIRDDGPPNALIAYPEDGRFDIPALVERARAWPGLEGMDLAREVSCTQS
YEWTETLWDRAHGFGRQNAPKFTVVAVDYGAKRNILRNLASAGCRVIVVPATASAEDILRHQPDGVFLSNGPGDPAATAE
YAVPAIRGVLDAGKPLFGICLGHQLLAHTLGAKTYKLARGHRGANQPVQELATGKVEITSQNHGFAVDEASLPDGVTVTH
RSLFDGSNEGIACPAKNCFSVQYHPEASPGPSDANHLFRRFVAMMEG
>Mature_446_residues
PKTTDEIIDLLGGADAAARLTQVSTEAVRKWRSAGAIPARHWPAVIAATGLSLADLSGDIAMESETTKPEGATAALVLGD
GRVFWGRGFGAHSTGEPAELCFSTGMTGYQETLTDPSFAGQIITFTFPHIGNVGANPEDIEANTSFARGLVINRDITRPS
NWRAAEGLAAWCRRMGLPGIAGVDTRALTRTIRDDGPPNALIAYPEDGRFDIPALVERARAWPGLEGMDLAREVSCTQSY
EWTETLWDRAHGFGRQNAPKFTVVAVDYGAKRNILRNLASAGCRVIVVPATASAEDILRHQPDGVFLSNGPGDPAATAEY
AVPAIRGVLDAGKPLFGICLGHQLLAHTLGAKTYKLARGHRGANQPVQELATGKVEITSQNHGFAVDEASLPDGVTVTHR
SLFDGSNEGIACPAKNCFSVQYHPEASPGPSDANHLFRRFVAMMEG

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=379, Percent_Identity=39.5778364116095, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI21361331, Length=393, Percent_Identity=35.8778625954198, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI169790915, Length=393, Percent_Identity=35.8778625954198, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1786215, Length=377, Percent_Identity=51.1936339522546, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI193204318, Length=381, Percent_Identity=38.0577427821522, Blast_Score=234, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6322331, Length=397, Percent_Identity=36.5239294710327, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6324878, Length=399, Percent_Identity=35.3383458646617, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI45555749, Length=388, Percent_Identity=37.3711340206186, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24642586, Length=388, Percent_Identity=37.3711340206186, Blast_Score=226, Evalue=3e-59,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 47590; Mature: 47459

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTTDEIIDLLGGADAAARLTQVSTEAVRKWRSAGAIPARHWPAVIAATGLSLADLSGD
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHCCCCHHHCCCC
IAMESETTKPEGATAALVLGDGRVFWGRGFGAHSTGEPAELCFSTGMTGYQETLTDPSFA
EEECCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCC
GQIITFTFPHIGNVGANPEDIEANTSFARGLVINRDITRPSNWRAAEGLAAWCRRMGLPG
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
IAGVDTRALTRTIRDDGPPNALIAYPEDGRFDIPALVERARAWPGLEGMDLAREVSCTQS
CCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCC
YEWTETLWDRAHGFGRQNAPKFTVVAVDYGAKRNILRNLASAGCRVIVVPATASAEDILR
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHH
HQPDGVFLSNGPGDPAATAEYAVPAIRGVLDAGKPLFGICLGHQLLAHTLGAKTYKLARG
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCC
HRGANQPVQELATGKVEITSQNHGFAVDEASLPDGVTVTHRSLFDGSNEGIACPAKNCFS
CCCCCCHHHHHHCCCEEEEECCCCEEEECCCCCCCCEEEEHHHCCCCCCCEECCCCCCEE
VQYHPEASPGPSDANHLFRRFVAMMEG
EEECCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKTTDEIIDLLGGADAAARLTQVSTEAVRKWRSAGAIPARHWPAVIAATGLSLADLSGD
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHCCCCHHHCCCC
IAMESETTKPEGATAALVLGDGRVFWGRGFGAHSTGEPAELCFSTGMTGYQETLTDPSFA
EEECCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCC
GQIITFTFPHIGNVGANPEDIEANTSFARGLVINRDITRPSNWRAAEGLAAWCRRMGLPG
CEEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCC
IAGVDTRALTRTIRDDGPPNALIAYPEDGRFDIPALVERARAWPGLEGMDLAREVSCTQS
CCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCC
YEWTETLWDRAHGFGRQNAPKFTVVAVDYGAKRNILRNLASAGCRVIVVPATASAEDILR
CCHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHH
HQPDGVFLSNGPGDPAATAEYAVPAIRGVLDAGKPLFGICLGHQLLAHTLGAKTYKLARG
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCC
HRGANQPVQELATGKVEITSQNHGFAVDEASLPDGVTVTHRSLFDGSNEGIACPAKNCFS
CCCCCCHHHHHHCCCEEEEECCCCEEEECCCCCCCCEEEEHHHCCCCCCCEECCCCCCEE
VQYHPEASPGPSDANHLFRRFVAMMEG
EEECCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA