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The map label for this gene is hfaC [H]

Identifier: 148259955

GI number: 148259955

Start: 1048289

End: 1050094

Strand: Reverse

Name: hfaC [H]

Synonym: Acry_0944

Alternate gene names: 148259955

Gene position: 1050094-1048289 (Counterclockwise)

Preceding gene: 148259957

Following gene: 148259923

Centisome position: 30.98

GC content: 69.77

Gene sequence:

>1806_bases
ATGGCTCCTCCCCTGCTCAACCTGCAAGACATAAGGCTCTCGCTCGGCGGCGCGCCGCTGCTCGACGGGGCGGAAATCGG
CATTGCCGCGGGCGAGCGGATCTGCCTCGTCGGGCGGAACGGATCGGGCAAGTCCACCCTGCTGAAGATCGCGGCGGGGC
TCGCCGAGGCCGATTCCGGCACGCGGTTCCTGCAGCCTGGCGCCACCCTGCGCTACCTGCCGCAGGAGCCGGACCTCACC
CGCTTCCCGACCGTGCTCGATTACGTGTTCGACGGTCTCGATCCGGAAGTGGACGGGCACCACGCCCGTGCCTGCCTCGA
CCGGCTTGGGCTGACCGGCGCCGAGAGTACCGCCCGCCTCTCCGGCGGCGAGGCGCGGCGGGCCGCGCTGGCCAAGGTGC
TGGCGCCGGAGCCCGATGTGCTGCTGCTCGACGAGCCGACGAACCATCTCGACCTGCCGGCGATCGAATGGCTGGAGGCC
GAGTTGAAGGCCTCGCGCGCCGGCATCGTGCTGATCAGCCATGACCGGCGGCTGCTGGAGACGGTGACGCGCAGCATCGT
CTGGCTCGATCGCGGCCGCACCAGCCGGATCGATCGCGGCTTCTCGCATTTCGAAGCCTGGCGCGACGAGGTGTTCGAGC
AGGAGGAGCGTGACGCGCAGAAGCTCTCCCGCGCCATCGCGCGCGAGGAGGACTGGATGCGCTATGGCGTGACGGCGCGG
CGCAAGCGCAATGTCCGCCGCGTTGCCGAACTCGCCGCCCTGCGCGCGCGCAAGCGCGAGGAGCGACGCGAGGCGCGGGA
GATGAACGTGACGACAAGTGCCGCCGCACTCTCCGGCAAGATCGTCGTCGATGCCGAGCACGTCTCGAAAACATTCGGCG
AGCGCTGCGTGATCCGCGACCTGACGCTACGGGTACTGCGTGGCGACCGGCTTGGCATCGTCGGGCCGAACGGTGCCGGC
AAGACCACCCTGCTGCGGCTGCTGACCGGGCAGATCGAGCCGGACTCAGGCACGATCACCCAGGGCACCAACCTTGCCGT
GGCGACCCTTGACCAGCAGCGCGCCGCCCTCGACCCGGCCCGCACCCTCGCCGACACGCTGACCGGAGGGGGGAGCGACA
TGGTCGAGGTCGGCGGGCAGTTTCGCCATGTCGTCGGCTACATGAAGGATTTCCTGTTCCGCCCCGAACAGGCGCGCACG
CCGGTCGGCACGCTGTCGGGCGGCGAGCGTGGCCGGCTGCTGCTGGCCTGCGCGATGGCACGGCCGTCGAACCTGCTGAT
CCTCGACGAACCGACCAACGATCTCGATCTCGAAACGCTCGACATCCTGCAGGATATGCTGTCGGACTATGCCGGCACGG
TGCTGCTGGTCAGCCATGACCGCGACTTTCTCGACCGCATCGCGACCTCCACGCTCGCGGCGGAGGGCGACGGGCGATGG
GTGGAGTATGCCGGCGGCTATGCGGACATGCTGGCCCAGCGCGGCCCGCGCGAGACGCGCGAGGCAGGGCCGCGCAAGCC
GGCCGCGCCGCCGCCGAAACCCAGGGCCGCGGCCTCGGCGTTCTCCTTCCGCGACCGTCACCGGCTCAAGGAACTCGAAA
GCGAGATGGAAACGCTTCAGGCCGGCATCGCCCGGCACGAGGCCCGCCTCGCCGACCCCGATTTCTTCACCCGCGATGCC
GATGGGTTCCGCAAGGCCAGTGAAACGGTAGGCGGACTCCAGGAGCGGCTCGCCGCGCTCGAGGCCGAATGGCTCGACCT
CGAACTCAGGCGCGAGACGGCGGATGAGGGGAAAACCTCATCGTGA

Upstream 100 bases:

>100_bases
AAGCGGCAGACGGATTTCGGTCAGGCGGATCATGGCAGCGCTCTCATACCCCGATCGGCGCTCGCTTGCCATGCGATCCG
CGATTGGCCACAAGGCGCGC

Downstream 100 bases:

>100_bases
TGCTGCGCGCGATGACCAGCACGATGATGACGACGACCAGCGTGATGATGTCTTCCGCCGAGAATTTCTGGCCGTAGAGC
TTGATCAGCACCTCACGGAG

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MAPPLLNLQDIRLSLGGAPLLDGAEIGIAAGERICLVGRNGSGKSTLLKIAAGLAEADSGTRFLQPGATLRYLPQEPDLT
RFPTVLDYVFDGLDPEVDGHHARACLDRLGLTGAESTARLSGGEARRAALAKVLAPEPDVLLLDEPTNHLDLPAIEWLEA
ELKASRAGIVLISHDRRLLETVTRSIVWLDRGRTSRIDRGFSHFEAWRDEVFEQEERDAQKLSRAIAREEDWMRYGVTAR
RKRNVRRVAELAALRARKREERREAREMNVTTSAAALSGKIVVDAEHVSKTFGERCVIRDLTLRVLRGDRLGIVGPNGAG
KTTLLRLLTGQIEPDSGTITQGTNLAVATLDQQRAALDPARTLADTLTGGGSDMVEVGGQFRHVVGYMKDFLFRPEQART
PVGTLSGGERGRLLLACAMARPSNLLILDEPTNDLDLETLDILQDMLSDYAGTVLLVSHDRDFLDRIATSTLAAEGDGRW
VEYAGGYADMLAQRGPRETREAGPRKPAAPPPKPRAAASAFSFRDRHRLKELESEMETLQAGIARHEARLADPDFFTRDA
DGFRKASETVGGLQERLAALEAEWLDLELRRETADEGKTSS

Sequences:

>Translated_601_residues
MAPPLLNLQDIRLSLGGAPLLDGAEIGIAAGERICLVGRNGSGKSTLLKIAAGLAEADSGTRFLQPGATLRYLPQEPDLT
RFPTVLDYVFDGLDPEVDGHHARACLDRLGLTGAESTARLSGGEARRAALAKVLAPEPDVLLLDEPTNHLDLPAIEWLEA
ELKASRAGIVLISHDRRLLETVTRSIVWLDRGRTSRIDRGFSHFEAWRDEVFEQEERDAQKLSRAIAREEDWMRYGVTAR
RKRNVRRVAELAALRARKREERREAREMNVTTSAAALSGKIVVDAEHVSKTFGERCVIRDLTLRVLRGDRLGIVGPNGAG
KTTLLRLLTGQIEPDSGTITQGTNLAVATLDQQRAALDPARTLADTLTGGGSDMVEVGGQFRHVVGYMKDFLFRPEQART
PVGTLSGGERGRLLLACAMARPSNLLILDEPTNDLDLETLDILQDMLSDYAGTVLLVSHDRDFLDRIATSTLAAEGDGRW
VEYAGGYADMLAQRGPRETREAGPRKPAAPPPKPRAAASAFSFRDRHRLKELESEMETLQAGIARHEARLADPDFFTRDA
DGFRKASETVGGLQERLAALEAEWLDLELRRETADEGKTSS
>Mature_600_residues
APPLLNLQDIRLSLGGAPLLDGAEIGIAAGERICLVGRNGSGKSTLLKIAAGLAEADSGTRFLQPGATLRYLPQEPDLTR
FPTVLDYVFDGLDPEVDGHHARACLDRLGLTGAESTARLSGGEARRAALAKVLAPEPDVLLLDEPTNHLDLPAIEWLEAE
LKASRAGIVLISHDRRLLETVTRSIVWLDRGRTSRIDRGFSHFEAWRDEVFEQEERDAQKLSRAIAREEDWMRYGVTARR
KRNVRRVAELAALRARKREERREAREMNVTTSAAALSGKIVVDAEHVSKTFGERCVIRDLTLRVLRGDRLGIVGPNGAGK
TTLLRLLTGQIEPDSGTITQGTNLAVATLDQQRAALDPARTLADTLTGGGSDMVEVGGQFRHVVGYMKDFLFRPEQARTP
VGTLSGGERGRLLLACAMARPSNLLILDEPTNDLDLETLDILQDMLSDYAGTVLLVSHDRDFLDRIATSTLAAEGDGRWV
EYAGGYADMLAQRGPRETREAGPRKPAAPPPKPRAAASAFSFRDRHRLKELESEMETLQAGIARHEARLADPDFFTRDAD
GFRKASETVGGLQERLAALEAEWLDLELRRETADEGKTSS

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=31.0861423220974, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI27881506, Length=513, Percent_Identity=27.0955165692008, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI10947137, Length=513, Percent_Identity=27.0955165692008, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI69354671, Length=360, Percent_Identity=28.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI10947135, Length=360, Percent_Identity=28.3333333333333, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI9955963, Length=252, Percent_Identity=30.5555555555556, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1787182, Length=632, Percent_Identity=38.6075949367089, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI2367384, Length=512, Percent_Identity=36.1328125, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1787041, Length=536, Percent_Identity=29.4776119402985, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789751, Length=629, Percent_Identity=29.8887122416534, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=30.5, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788225, Length=218, Percent_Identity=29.3577981651376, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=33.5078534031414, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788761, Length=217, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787164, Length=182, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081791, Length=200, Percent_Identity=28.5, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=214, Percent_Identity=29.9065420560748, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786698, Length=197, Percent_Identity=31.9796954314721, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786563, Length=188, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786703, Length=155, Percent_Identity=36.7741935483871, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787105, Length=212, Percent_Identity=32.5471698113208, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790190, Length=196, Percent_Identity=31.1224489795918, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081709, Length=207, Percent_Identity=27.0531400966184, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790739, Length=195, Percent_Identity=30.2564102564103, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789586, Length=197, Percent_Identity=31.9796954314721, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787792, Length=191, Percent_Identity=32.4607329842932, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=183, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=513, Percent_Identity=30.6042884990253, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=25.9047619047619, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17559834, Length=388, Percent_Identity=27.319587628866, Blast_Score=145, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320874, Length=542, Percent_Identity=26.5682656826568, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321121, Length=399, Percent_Identity=30.0751879699248, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6325030, Length=360, Percent_Identity=28.6111111111111, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=352, Percent_Identity=26.4204545454545, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323278, Length=356, Percent_Identity=26.9662921348315, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322640, Length=219, Percent_Identity=28.7671232876712, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642252, Length=537, Percent_Identity=27.7467411545624, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI18859989, Length=537, Percent_Identity=27.7467411545624, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24641342, Length=553, Percent_Identity=26.7631103074141, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=28.4332688588008, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI116007184, Length=172, Percent_Identity=33.1395348837209, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221500365, Length=172, Percent_Identity=33.1395348837209, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643674, Length=227, Percent_Identity=25.9911894273128, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666092, Length=193, Percent_Identity=29.5336787564767, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 65889; Mature: 65758

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPLLNLQDIRLSLGGAPLLDGAEIGIAAGERICLVGRNGSGKSTLLKIAAGLAEADSG
CCCCCCCHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCC
TRFLQPGATLRYLPQEPDLTRFPTVLDYVFDGLDPEVDGHHARACLDRLGLTGAESTARL
CEEECCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHC
SGGEARRAALAKVLAPEPDVLLLDEPTNHLDLPAIEWLEAELKASRAGIVLISHDRRLLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHH
TVTRSIVWLDRGRTSRIDRGFSHFEAWRDEVFEQEERDAQKLSRAIAREEDWMRYGVTAR
HHHHHHEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNVRRVAELAALRARKREERREAREMNVTTSAAALSGKIVVDAEHVSKTFGERCVIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEHHHHHHHHHCHHHHHH
LTLRVLRGDRLGIVGPNGAGKTTLLRLLTGQIEPDSGTITQGTNLAVATLDQQRAALDPA
HHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEECCCCEEEEECCHHHHHCCHH
RTLADTLTGGGSDMVEVGGQFRHVVGYMKDFLFRPEQARTPVGTLSGGERGRLLLACAMA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECC
RPSNLLILDEPTNDLDLETLDILQDMLSDYAGTVLLVSHDRDFLDRIATSTLAAEGDGRW
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCE
VEYAGGYADMLAQRGPRETREAGPRKPAAPPPKPRAAASAFSFRDRHRLKELESEMETLQ
EEECCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGIARHEARLADPDFFTRDADGFRKASETVGGLQERLAALEAEWLDLELRRETADEGKTS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C
>Mature Secondary Structure 
APPLLNLQDIRLSLGGAPLLDGAEIGIAAGERICLVGRNGSGKSTLLKIAAGLAEADSG
CCCCCCHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCC
TRFLQPGATLRYLPQEPDLTRFPTVLDYVFDGLDPEVDGHHARACLDRLGLTGAESTARL
CEEECCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHC
SGGEARRAALAKVLAPEPDVLLLDEPTNHLDLPAIEWLEAELKASRAGIVLISHDRRLLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHH
TVTRSIVWLDRGRTSRIDRGFSHFEAWRDEVFEQEERDAQKLSRAIAREEDWMRYGVTAR
HHHHHHEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNVRRVAELAALRARKREERREAREMNVTTSAAALSGKIVVDAEHVSKTFGERCVIRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEEHHHHHHHHHCHHHHHH
LTLRVLRGDRLGIVGPNGAGKTTLLRLLTGQIEPDSGTITQGTNLAVATLDQQRAALDPA
HHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEECCCCEEEEECCHHHHHCCHH
RTLADTLTGGGSDMVEVGGQFRHVVGYMKDFLFRPEQARTPVGTLSGGERGRLLLACAMA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCEEEEEECC
RPSNLLILDEPTNDLDLETLDILQDMLSDYAGTVLLVSHDRDFLDRIATSTLAAEGDGRW
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCCE
VEYAGGYADMLAQRGPRETREAGPRKPAAPPPKPRAAASAFSFRDRHRLKELESEMETLQ
EEECCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGIARHEARLADPDFFTRDADGFRKASETVGGLQERLAALEAEWLDLELRRETADEGKTS
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]