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The map label for this gene is adh [H]

Identifier: 148259854

GI number: 148259854

Start: 931608

End: 932681

Strand: Reverse

Name: adh [H]

Synonym: Acry_0843

Alternate gene names: 148259854

Gene position: 932681-931608 (Counterclockwise)

Preceding gene: 148259855

Following gene: 148259853

Centisome position: 27.52

GC content: 70.48

Gene sequence:

>1074_bases
ATGTCCGCCACGATGAAAGCCTGGGCCGTTGTCGAGAACGGGGCGCCGCTGAAGGAAATCGACCTGCCGATGCCGGAGCC
GACGGGGCGGGAGATTTTGCTGGAGGTGACGCATTGCGGCGTCTGCCATTCCGACCTGCATCTCTGGGACGGGTATTACG
ACCTCGGCAGCGCCGGGCGCTACGAGATCGTGCAGCGCGGGATCACGCTGCCGCTGGCGCTGGGCCACGAGATCGTCGGC
CGGGTGGTGAAGCTCGGGCCGGAGGCGAGCGGGGTGAAGGTGGGGGATGTGCGGATCGTGTATCCCTGGGTCGGCTGCGG
CGAATGCGCGCGGTGCAAGGCGGGCGAGGACAATCTCTGCGCCAAGCAGCGCTCGCTCGGCATCTACCAGCATGGCGGCT
ACGCGACCCATGTGATCGCGGCGCATGCGGGGCACCTCGTCGATCCCGGCGATCTCGATCCGGCGCTGGCGGCGACCTAT
GCGTGTTCGGGCATCACGGTCTATGCCGCGATCCGCAAGGTGATGCCGCTGCCGGCGGACACGCCGGTGGTGCTGATCGG
CGCGGGCGGGCTCGGGCTTTCGGCGATTGCGGTGCTGCGCGCGCTCGGGCACAAGGCGATCGTCAGCGTCGATACCAGTG
CGAGGAAGCGCGAGGCGGCGCTGGCGGCGGGGGCCACCGCGGTGGTGGACGGCAACGACCCGGCGCTGCACAAGGCGATC
ATCGCGGCGTGCGGCGGGCAGCCGGAGGCGATCATCGACCTCGTCAACGGCTCGGGCACGGCGAAGGCGGCGCATGCGGC
GCTGGCCAAGGGCGGCAAGCTGATCATGGTCGGGCTGTTCGGCGGCGAGCTGAACATACCCCTGCCCTTCATGCCGATGC
GGGCGCTGACGTTGCAGGGCAGCTTCGTCGGCACGCCGGGCGATCTGCGCGAGCTGGTGGATCTCGCCCAGGGCGGGGCG
CTGCCGAAGCTGCAGATCGAGACCGTGCCGCAGCGCGAGGCGGACGCGGCGATCCACCGGCTCAAGGCCGGGGATGTGAC
CGGGCGGCTGGTGCTGGTGGCCGACGGCGCGTGA

Upstream 100 bases:

>100_bases
CGCCGGCGCAGGGCTGATCCCCCTCGCCTTCCGGCCTGCCCGGCTTGCCTGAACCGCGCGATCCACCCGATACTCGCGCG
GAGCAAAAAGGGAGACCGGA

Downstream 100 bases:

>100_bases
TCGACAAGCTCGAATACCTGCTCGCGCTGGCGCGGGAGGAGCATTTCGGCCGCGGCGCCGAAAGCTGCGGCGTGACCCAG
CCCACCTTCTCGGCGGGCAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSATMKAWAVVENGAPLKEIDLPMPEPTGREILLEVTHCGVCHSDLHLWDGYYDLGSAGRYEIVQRGITLPLALGHEIVG
RVVKLGPEASGVKVGDVRIVYPWVGCGECARCKAGEDNLCAKQRSLGIYQHGGYATHVIAAHAGHLVDPGDLDPALAATY
ACSGITVYAAIRKVMPLPADTPVVLIGAGGLGLSAIAVLRALGHKAIVSVDTSARKREAALAAGATAVVDGNDPALHKAI
IAACGGQPEAIIDLVNGSGTAKAAHAALAKGGKLIMVGLFGGELNIPLPFMPMRALTLQGSFVGTPGDLRELVDLAQGGA
LPKLQIETVPQREADAAIHRLKAGDVTGRLVLVADGA

Sequences:

>Translated_357_residues
MSATMKAWAVVENGAPLKEIDLPMPEPTGREILLEVTHCGVCHSDLHLWDGYYDLGSAGRYEIVQRGITLPLALGHEIVG
RVVKLGPEASGVKVGDVRIVYPWVGCGECARCKAGEDNLCAKQRSLGIYQHGGYATHVIAAHAGHLVDPGDLDPALAATY
ACSGITVYAAIRKVMPLPADTPVVLIGAGGLGLSAIAVLRALGHKAIVSVDTSARKREAALAAGATAVVDGNDPALHKAI
IAACGGQPEAIIDLVNGSGTAKAAHAALAKGGKLIMVGLFGGELNIPLPFMPMRALTLQGSFVGTPGDLRELVDLAQGGA
LPKLQIETVPQREADAAIHRLKAGDVTGRLVLVADGA
>Mature_356_residues
SATMKAWAVVENGAPLKEIDLPMPEPTGREILLEVTHCGVCHSDLHLWDGYYDLGSAGRYEIVQRGITLPLALGHEIVGR
VVKLGPEASGVKVGDVRIVYPWVGCGECARCKAGEDNLCAKQRSLGIYQHGGYATHVIAAHAGHLVDPGDLDPALAATYA
CSGITVYAAIRKVMPLPADTPVVLIGAGGLGLSAIAVLRALGHKAIVSVDTSARKREAALAAGATAVVDGNDPALHKAII
AACGGQPEAIIDLVNGSGTAKAAHAALAKGGKLIMVGLFGGELNIPLPFMPMRALTLQGSFVGTPGDLRELVDLAQGGAL
PKLQIETVPQREADAAIHRLKAGDVTGRLVLVADGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=308, Percent_Identity=26.2987012987013, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI226510992, Length=300, Percent_Identity=30, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082401, Length=357, Percent_Identity=30.5322128851541, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=27.4691358024691, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790045, Length=303, Percent_Identity=25.7425742574257, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786518, Length=363, Percent_Identity=27.5482093663912, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788073, Length=305, Percent_Identity=25.5737704918033, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787863, Length=274, Percent_Identity=24.8175182481752, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790718, Length=323, Percent_Identity=25.3869969040248, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786552, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082125, Length=368, Percent_Identity=23.6413043478261, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788075, Length=323, Percent_Identity=24.4582043343653, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788407, Length=204, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=270, Percent_Identity=27.037037037037, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=356, Percent_Identity=28.0898876404494, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71988145, Length=350, Percent_Identity=27.4285714285714, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17562582, Length=357, Percent_Identity=27.1708683473389, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562876, Length=299, Percent_Identity=27.4247491638796, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=293, Percent_Identity=26.6211604095563, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=357, Percent_Identity=29.1316526610644, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319621, Length=354, Percent_Identity=28.2485875706215, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324486, Length=357, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323729, Length=358, Percent_Identity=28.4916201117318, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6323980, Length=348, Percent_Identity=27.2988505747126, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319258, Length=331, Percent_Identity=27.4924471299094, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319949, Length=350, Percent_Identity=27.7142857142857, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319257, Length=337, Percent_Identity=28.486646884273, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=331, Percent_Identity=27.4924471299094, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=376, Percent_Identity=26.063829787234, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=331, Percent_Identity=27.4924471299094, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323099, Length=325, Percent_Identity=24.9230769230769, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17137530, Length=293, Percent_Identity=27.9863481228669, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737897, Length=305, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737895, Length=341, Percent_Identity=24.633431085044, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36809; Mature: 36678

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATMKAWAVVENGAPLKEIDLPMPEPTGREILLEVTHCGVCHSDLHLWDGYYDLGSAGR
CCCCCEEEEEEECCCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCH
YEIVQRGITLPLALGHEIVGRVVKLGPEASGVKVGDVRIVYPWVGCGECARCKAGEDNLC
HHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCCHHCCCCCCCCHH
AKQRSLGIYQHGGYATHVIAAHAGHLVDPGDLDPALAATYACSGITVYAAIRKVMPLPAD
HHHHCCCEEECCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
TPVVLIGAGGLGLSAIAVLRALGHKAIVSVDTSARKREAALAAGATAVVDGNDPALHKAI
CCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEECCCHHHHHHH
IAACGGQPEAIIDLVNGSGTAKAAHAALAKGGKLIMVGLFGGELNIPLPFMPMRALTLQG
HHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEECCCCCCCCCEEEEECC
SFVGTPGDLRELVDLAQGGALPKLQIETVPQREADAAIHRLKAGDVTGRLVLVADGA
CEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure 
SATMKAWAVVENGAPLKEIDLPMPEPTGREILLEVTHCGVCHSDLHLWDGYYDLGSAGR
CCCCEEEEEEECCCCHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCH
YEIVQRGITLPLALGHEIVGRVVKLGPEASGVKVGDVRIVYPWVGCGECARCKAGEDNLC
HHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCCHHCCCCCCCCHH
AKQRSLGIYQHGGYATHVIAAHAGHLVDPGDLDPALAATYACSGITVYAAIRKVMPLPAD
HHHHCCCEEECCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCC
TPVVLIGAGGLGLSAIAVLRALGHKAIVSVDTSARKREAALAAGATAVVDGNDPALHKAI
CCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCEEEEECCCHHHHHHH
IAACGGQPEAIIDLVNGSGTAKAAHAALAKGGKLIMVGLFGGELNIPLPFMPMRALTLQG
HHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCEECCCCCCCCCEEEEECC
SFVGTPGDLRELVDLAQGGALPKLQIETVPQREADAAIHRLKAGDVTGRLVLVADGA
CEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]