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The map label for this gene is nuoE [H]

Identifier: 148259852

GI number: 148259852

Start: 930098

End: 930571

Strand: Reverse

Name: nuoE [H]

Synonym: Acry_0841

Alternate gene names: 148259852

Gene position: 930571-930098 (Counterclockwise)

Preceding gene: 148259853

Following gene: 148259851

Centisome position: 27.46

GC content: 70.25

Gene sequence:

>474_bases
ATGGACCCAAAGCCCGCTGAATGGAATGACGAGGCCGCCCGCGCCGTGATCCGGGATTACCTGGGCGAGGAAGGGCCGCT
GCTGCCGATCCTTCACGCGCTGCAGGAGAATTTCGGCTTCATCCCGCGCGAGGCCGAGCCGCTGATCGCCGACATGCTCA
ACATCACCCGCGCCGAGGTGCATGGCGTGATCAGCTTCTACCACGATTTCCGCCGCGCGCCGGCGGGCCGCCACGTGCTG
AAGCTGTGCCGGGCGGAGGCCTGCCAGTCGATGGGGTCGGAGGCGAATGCGCGCCGCCTGCTGGACGCGCTCGGGCTCGA
ATGGGGCGGCACCACGCCGGACGGGCGGATCACCGTCGAGGCGGTGTATTGCCTTGGCCTGTGCGCCACGGCGCCGAGCG
CGCTGTTCGACGACGAGCCGGTGGGACGGGCGGATGCCGCCACCCTTGAAGCCCTGGTCGCGGAGGCCGCGTGA

Upstream 100 bases:

>100_bases
GCGGGAAGATCATGTGGATAATGCACACGAAAGATTAACCTGCCCGATTTAAGCAGGAGGTTCGGTCATCCCGGCCGAGC
GAGGAAACAGGACTGTCGGA

Downstream 100 bases:

>100_bases
TGAAGATTTTCGTGCCGCAGGACATGGCCGCCGTGGCGGTCGGGGCGAACCGGGTGGCCGCGGCGATCGAGGCCGAGGCG
CGGGCGCGCAACATTCCGGT

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDPKPAEWNDEAARAVIRDYLGEEGPLLPILHALQENFGFIPREAEPLIADMLNITRAEVHGVISFYHDFRRAPAGRHVL
KLCRAEACQSMGSEANARRLLDALGLEWGGTTPDGRITVEAVYCLGLCATAPSALFDDEPVGRADAATLEALVAEAA

Sequences:

>Translated_157_residues
MDPKPAEWNDEAARAVIRDYLGEEGPLLPILHALQENFGFIPREAEPLIADMLNITRAEVHGVISFYHDFRRAPAGRHVL
KLCRAEACQSMGSEANARRLLDALGLEWGGTTPDGRITVEAVYCLGLCATAPSALFDDEPVGRADAATLEALVAEAA
>Mature_157_residues
MDPKPAEWNDEAARAVIRDYLGEEGPLLPILHALQENFGFIPREAEPLIADMLNITRAEVHGVISFYHDFRRAPAGRHVL
KLCRAEACQSMGSEANARRLLDALGLEWGGTTPDGRITVEAVYCLGLCATAPSALFDDEPVGRADAATLEALVAEAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=149, Percent_Identity=27.5167785234899, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1788621, Length=109, Percent_Identity=35.7798165137615, Blast_Score=76, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561328, Length=133, Percent_Identity=32.3308270676692, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859877, Length=117, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355353, Length=132, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 16982; Mature: 16982

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPKPAEWNDEAARAVIRDYLGEEGPLLPILHALQENFGFIPREAEPLIADMLNITRAEV
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HGVISFYHDFRRAPAGRHVLKLCRAEACQSMGSEANARRLLDALGLEWGGTTPDGRITVE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
AVYCLGLCATAPSALFDDEPVGRADAATLEALVAEAA
HHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDPKPAEWNDEAARAVIRDYLGEEGPLLPILHALQENFGFIPREAEPLIADMLNITRAEV
CCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HGVISFYHDFRRAPAGRHVLKLCRAEACQSMGSEANARRLLDALGLEWGGTTPDGRITVE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHH
AVYCLGLCATAPSALFDDEPVGRADAATLEALVAEAA
HHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]