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The map label for this gene is engA [H]

Identifier: 148259762

GI number: 148259762

Start: 839943

End: 841298

Strand: Reverse

Name: engA [H]

Synonym: Acry_0750

Alternate gene names: 148259762

Gene position: 841298-839943 (Counterclockwise)

Preceding gene: 148259763

Following gene: 148259757

Centisome position: 24.82

GC content: 70.13

Gene sequence:

>1356_bases
ATGACCACCTCCCCTGCCCGCACCCCGCGGGTCGCGATCTGCGGGCGGCCGAATGTCGGCAAATCCACCCTGTTCAACCG
GTTGGCGGGCAAGCGTATCGCGCTCGTCGCCGACGAGCCGGGGGTCACGCGCGACCGCAAGGAAGCCTGGGGCGAGCTTG
CCGGGGTGAAGGTGCAGCTGATCGACACCGCGGGGCTTGAGGAAGCGCCGCCGGACACGCTGCCGGGCCGGATGCGCGCC
TCGACCGGGACGGCGGTGGACGAGGCGGATCTCGTGCTGTTCGTGTTCGACGCCCGCGCCGGCCTGCTGCCGGAGGACCG
GCATTTCGCCGCCTGGCTGCGCCGGGCGGGCAAGCCGGTGATCGTCGTCGCCAACAAGGCGGAGGGGCGCGGCGGCAGCA
ACGCGGCGCTGGAGGCCTATGAACTCGGCCTCGGCGAGCCGGTGGCGGTATCCGCCGAGCATAACGAGGGCGTGTCCGAC
CTGATCGACCGCATCATCGAGGCGCTGCCCGAGACGGACGAGGCGGAGGATGAGGATGGCGAACGGCCGATGCACCTCGC
CATCGTCGGGCGGCCGAATGCCGGAAAGTCGACCCTGATGAACCGGCTGCTGGGCGAGCAGCGGGTGATCACCGGCCCGG
AACCCGGCCTGACCCGCGATGCGATCGCCGCCGAACTGACCGATTCGGCCGGGCGGCGCTACCGGCTGTTCGACACCGCC
GGGCTGCGCCGGCGCGCGCGGGTCGAGGCGGGGCTGGAGAAACTCTCCACCTCATCGACGATCGAGGCGCTGAAATTCGC
CGATACGGTGGTGCTCGCGATCGATGCGCATGAGGGGCTGCACGACCAGGATTTCACCATTGCCCGGCTGATCGAGCGCG
AGGGCCGCGCCTGCGTCATCGCGCTGACCAAGTGGGACCTGGTGGAAGACCGCGACCGCACCCGCCGCGCGATTCTCGAA
CGGCTGGAACACTCGCTCTCGCAGATGAAGGGGATCACGCTGGTGCCGCTCTCGGGCGAGACCGGCGAGGGTGTCAAGAA
ACTGCTGCCGGCGGTGCGCGAGGCGGACCGCATCTGGAACACGCGGGTCACCACCTCCGCACTCAACCGCTGGTTCGAGG
GCGCGCTGGAACGCTTCCCGCCGCCGCTGGTCGAGGGGCGCCGGCTCAAGCTGCGCTATATCACCCAGGTCAAGGCGCGG
CCGCCCAGCTTCGCGGTGTTCGGCACCAGGGCGGAACTCACGCCCGACAGCTACCAGCGCTACCTCGTCAATTCGCTGCG
CGAGCGGTTCGGCCTCGAAGGCACGCCGATCCGCCTCGCGTTGCGCGGCACCAAGAACCCCTACGCCGACGAGTAA

Upstream 100 bases:

>100_bases
CCGCCGGCCTCGCGCTCGACGGAGAGGCCGATCTTGCCCCGATCGCCGCCGCGGGAACGCTGTTCGCGCTGACCCGCAAC
GCGGTGCTGACCGCCTATCG

Downstream 100 bases:

>100_bases
CCGGGCCGGCGCATGCCGCTAGTGTCCCGAATCTGAAATTCACCCACGAATTTCAGGCGCAGGACACCAGTGCATCATCC
GATCCAACAGGATCGGAAAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTTSPARTPRVAICGRPNVGKSTLFNRLAGKRIALVADEPGVTRDRKEAWGELAGVKVQLIDTAGLEEAPPDTLPGRMRA
STGTAVDEADLVLFVFDARAGLLPEDRHFAAWLRRAGKPVIVVANKAEGRGGSNAALEAYELGLGEPVAVSAEHNEGVSD
LIDRIIEALPETDEAEDEDGERPMHLAIVGRPNAGKSTLMNRLLGEQRVITGPEPGLTRDAIAAELTDSAGRRYRLFDTA
GLRRRARVEAGLEKLSTSSTIEALKFADTVVLAIDAHEGLHDQDFTIARLIEREGRACVIALTKWDLVEDRDRTRRAILE
RLEHSLSQMKGITLVPLSGETGEGVKKLLPAVREADRIWNTRVTTSALNRWFEGALERFPPPLVEGRRLKLRYITQVKAR
PPSFAVFGTRAELTPDSYQRYLVNSLRERFGLEGTPIRLALRGTKNPYADE

Sequences:

>Translated_451_residues
MTTSPARTPRVAICGRPNVGKSTLFNRLAGKRIALVADEPGVTRDRKEAWGELAGVKVQLIDTAGLEEAPPDTLPGRMRA
STGTAVDEADLVLFVFDARAGLLPEDRHFAAWLRRAGKPVIVVANKAEGRGGSNAALEAYELGLGEPVAVSAEHNEGVSD
LIDRIIEALPETDEAEDEDGERPMHLAIVGRPNAGKSTLMNRLLGEQRVITGPEPGLTRDAIAAELTDSAGRRYRLFDTA
GLRRRARVEAGLEKLSTSSTIEALKFADTVVLAIDAHEGLHDQDFTIARLIEREGRACVIALTKWDLVEDRDRTRRAILE
RLEHSLSQMKGITLVPLSGETGEGVKKLLPAVREADRIWNTRVTTSALNRWFEGALERFPPPLVEGRRLKLRYITQVKAR
PPSFAVFGTRAELTPDSYQRYLVNSLRERFGLEGTPIRLALRGTKNPYADE
>Mature_450_residues
TTSPARTPRVAICGRPNVGKSTLFNRLAGKRIALVADEPGVTRDRKEAWGELAGVKVQLIDTAGLEEAPPDTLPGRMRAS
TGTAVDEADLVLFVFDARAGLLPEDRHFAAWLRRAGKPVIVVANKAEGRGGSNAALEAYELGLGEPVAVSAEHNEGVSDL
IDRIIEALPETDEAEDEDGERPMHLAIVGRPNAGKSTLMNRLLGEQRVITGPEPGLTRDAIAAELTDSAGRRYRLFDTAG
LRRRARVEAGLEKLSTSSTIEALKFADTVVLAIDAHEGLHDQDFTIARLIEREGRACVIALTKWDLVEDRDRTRRAILER
LEHSLSQMKGITLVPLSGETGEGVKKLLPAVREADRIWNTRVTTSALNRWFEGALERFPPPLVEGRRLKLRYITQVKARP
PSFAVFGTRAELTPDSYQRYLVNSLRERFGLEGTPIRLALRGTKNPYADE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=471, Percent_Identity=41.1889596602972, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788919, Length=170, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI2367268, Length=168, Percent_Identity=36.3095238095238, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=164, Percent_Identity=34.1463414634146, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49552; Mature: 49421

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSPARTPRVAICGRPNVGKSTLFNRLAGKRIALVADEPGVTRDRKEAWGELAGVKVQL
CCCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEE
IDTAGLEEAPPDTLPGRMRASTGTAVDEADLVLFVFDARAGLLPEDRHFAAWLRRAGKPV
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCE
IVVANKAEGRGGSNAALEAYELGLGEPVAVSAEHNEGVSDLIDRIIEALPETDEAEDEDG
EEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
ERPMHLAIVGRPNAGKSTLMNRLLGEQRVITGPEPGLTRDAIAAELTDSAGRRYRLFDTA
CCCEEEEEEECCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECC
GLRRRARVEAGLEKLSTSSTIEALKFADTVVLAIDAHEGLHDQDFTIARLIEREGRACVI
CHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEE
ALTKWDLVEDRDRTRRAILERLEHSLSQMKGITLVPLSGETGEGVKKLLPAVREADRIWN
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
TRVTTSALNRWFEGALERFPPPLVEGRRLKLRYITQVKARPPSFAVFGTRAELTPDSYQR
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHH
YLVNSLRERFGLEGTPIRLALRGTKNPYADE
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TTSPARTPRVAICGRPNVGKSTLFNRLAGKRIALVADEPGVTRDRKEAWGELAGVKVQL
CCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEE
IDTAGLEEAPPDTLPGRMRASTGTAVDEADLVLFVFDARAGLLPEDRHFAAWLRRAGKPV
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCE
IVVANKAEGRGGSNAALEAYELGLGEPVAVSAEHNEGVSDLIDRIIEALPETDEAEDEDG
EEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCC
ERPMHLAIVGRPNAGKSTLMNRLLGEQRVITGPEPGLTRDAIAAELTDSAGRRYRLFDTA
CCCEEEEEEECCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECC
GLRRRARVEAGLEKLSTSSTIEALKFADTVVLAIDAHEGLHDQDFTIARLIEREGRACVI
CHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEE
ALTKWDLVEDRDRTRRAILERLEHSLSQMKGITLVPLSGETGEGVKKLLPAVREADRIWN
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
TRVTTSALNRWFEGALERFPPPLVEGRRLKLRYITQVKARPPSFAVFGTRAELTPDSYQR
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCCHHHHHH
YLVNSLRERFGLEGTPIRLALRGTKNPYADE
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA