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The map label for this gene is icfA [H]

Identifier: 148259679

GI number: 148259679

Start: 752922

End: 753545

Strand: Reverse

Name: icfA [H]

Synonym: Acry_0666

Alternate gene names: 148259679

Gene position: 753545-752922 (Counterclockwise)

Preceding gene: 148259691

Following gene: 148259678

Centisome position: 22.23

GC content: 70.83

Gene sequence:

>624_bases
ATGGAAGAGCTTCTGGCAGGGTATCGGCGGTTCCGCGCGGCGCGCTGGCCGGCGCAGCGGGAAACCCTGGAGGCCCTGGC
GCGCGACGGGCAGAAGCCGCACACGCTGGCGATCGCCTGCTGCGATTCCCGCGTCGCGCCGGAGATGATCTTCGACTGCG
CCCCCGGCGACGTGTTCACGGTGCGCAATATCGCCAATCTGGTGCCGCCCTACGCGCCGGACACCGCCAATCACGGCACC
TCGGCGGCGCTGGAATTCGCGGTGCGGGTGCTGCGGGTGCGGCGCATCGCGGTGATCGGCCATTCCTCCTGCGGCGGCAT
CGCGGCGCTGCTGCACGAACCCCCGCCCGAGGCGCGCGACTTCGTGGCGAACTGGGTGCGGATCGCCGAACCCGCCCGCA
AGCGCGCCGTGCGCTTCGCCGATGACCCGGTGGAAGCCGCCCGCCGCGCCGAAATCGAAAGCGTGCGGGTCTCGCTCGAG
AATCTCATGACCTTCCCCTGGATCGCCTCCGCGCACAACGCGGGCGAACTCGGCGTCTATGGCTTCTATTTCGACGTTCC
GAGCGGCACGCTGCGCGAGGTGACGGCGGAGGGCGAGCGGCTGATCACCGAGGGCGCGGGCTGA

Upstream 100 bases:

>100_bases
GGGACGGCGAAGGCGGCCCCGCCGCGTCATGATATGAGACGATGTTTGCCGCAGCGCGGCATGGATGATAAGCGGAACGC
TGTCTTGAGGAGGGGCCCGG

Downstream 100 bases:

>100_bases
GCCCGAGCGCGCGCAGGCACGCCCCAGCACAGAAAGGCATGGCGATGGAAACGGCAGATCGGAAGGCCGACCGCAAATCG
ATCGGATCGTGGGAACGCGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MEELLAGYRRFRAARWPAQRETLEALARDGQKPHTLAIACCDSRVAPEMIFDCAPGDVFTVRNIANLVPPYAPDTANHGT
SAALEFAVRVLRVRRIAVIGHSSCGGIAALLHEPPPEARDFVANWVRIAEPARKRAVRFADDPVEAARRAEIESVRVSLE
NLMTFPWIASAHNAGELGVYGFYFDVPSGTLREVTAEGERLITEGAG

Sequences:

>Translated_207_residues
MEELLAGYRRFRAARWPAQRETLEALARDGQKPHTLAIACCDSRVAPEMIFDCAPGDVFTVRNIANLVPPYAPDTANHGT
SAALEFAVRVLRVRRIAVIGHSSCGGIAALLHEPPPEARDFVANWVRIAEPARKRAVRFADDPVEAARRAEIESVRVSLE
NLMTFPWIASAHNAGELGVYGFYFDVPSGTLREVTAEGERLITEGAG
>Mature_207_residues
MEELLAGYRRFRAARWPAQRETLEALARDGQKPHTLAIACCDSRVAPEMIFDCAPGDVFTVRNIANLVPPYAPDTANHGT
SAALEFAVRVLRVRRIAVIGHSSCGGIAALLHEPPPEARDFVANWVRIAEPARKRAVRFADDPVEAARRAEIESVRVSLE
NLMTFPWIASAHNAGELGVYGFYFDVPSGTLREVTAEGERLITEGAG

Specific function: Reversible hydration of carbon dioxide. Essential to photosynthetic carbon dioxide fixation [H]

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=193, Percent_Identity=35.7512953367876, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786318, Length=175, Percent_Identity=30.2857142857143, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=196, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 22664; Mature: 22664

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELLAGYRRFRAARWPAQRETLEALARDGQKPHTLAIACCDSRVAPEMIFDCAPGDVFT
CHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEH
VRNIANLVPPYAPDTANHGTSAALEFAVRVLRVRRIAVIGHSSCGGIAALLHEPPPEARD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHH
FVANWVRIAEPARKRAVRFADDPVEAARRAEIESVRVSLENLMTFPWIASAHNAGELGVY
HHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEE
GFYFDVPSGTLREVTAEGERLITEGAG
EEEEECCCCHHHHHHHCCCCHHCCCCC
>Mature Secondary Structure
MEELLAGYRRFRAARWPAQRETLEALARDGQKPHTLAIACCDSRVAPEMIFDCAPGDVFT
CHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCEEH
VRNIANLVPPYAPDTANHGTSAALEFAVRVLRVRRIAVIGHSSCGGIAALLHEPPPEARD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCCCHHHH
FVANWVRIAEPARKRAVRFADDPVEAARRAEIESVRVSLENLMTFPWIASAHNAGELGVY
HHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEE
GFYFDVPSGTLREVTAEGERLITEGAG
EEEEECCCCHHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584776 [H]