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The map label for this gene is htrB [C]

Identifier: 148259662

GI number: 148259662

Start: 732034

End: 732921

Strand: Reverse

Name: htrB [C]

Synonym: Acry_0649

Alternate gene names: 148259662

Gene position: 732921-732034 (Counterclockwise)

Preceding gene: 148259663

Following gene: 148259661

Centisome position: 21.63

GC content: 72.07

Gene sequence:

>888_bases
ATGAGCCTCCTGCACAAGATCGAAACCACCGCGGCACGCGCCTTCCTCGGCATCTTCCGCGCCCTTGGCCCGCGTGCCGC
GAGCAACCTCGCCGGCGCGCTCGGCCGCGGCATCGGCCCGCTGATCCCCACCTCGCGCGTCGCCGATCAGAATCTCCGCC
GCGCCATGCCGGAACTCGACGAGGCCGCGCGCCGCCGCATCATCCGCGAGGTGTGGGAGAGCCTCGCCCGCACTGCCGGC
GAATTCCCGCATCTCGCCGCCCTGCGCGAAACCGATGCCGGCCCCGGCTACGAGATCGTCGGCCGCGAGCATTGCCTGGC
CCTCGCCGCGCAGGGCGGCCCGGCGCTCATCTTCACCGCGCATTTCGGCAACTGGGAGCTGATCCCGCCGGTGCTGCACC
GGCTCGGCGTCAGGCTCGCCTTCTTCTACCGCGCCGCCGCCAACCCGGCGGTCGACCGCCTGATCCTCGACCTGCGCGAG
CAGGCCACCGGCGAGCCGGTCACCATGTTCGCCAAGGGCGCCGCCGGCGCGCGCGGCTCCTATGCCCATCTGGTGCGCGG
CGGCATTCTCGGCATGCTGATGGACCAGAAGCTGAACGACGGCATCGCCTCGCCGCTGTTCGGAATCGACGCGATGACCG
CCCCGGCGCTGGCCGTCTTCGCCCGCAAGTTCCGCTGCCCGATCCTGCCGGTGCGCGCGGAACGCATCGGCCCGGCGCGC
ATCCGCATCGTCTTCGAGAAGCTGCACCGGATCGAGGTCACCGACGACCGCGAGGCCGACATCGCCGCCGGCACCGCCTG
GATGAACGCGACGATCGAGCGCTGGGTGCGCCAGCGTCCCGGCCAGTGGCTCTGGCTGCACCGGCGCTGGCCAAAGCCGG
TGGCCTAA

Upstream 100 bases:

>100_bases
AGGACGCGGTGAAACTGCCGCCGGCATTCCGCGCACGCTGCGCGGTGATCGAGGCGGGGCTTGCCTTCGACGACCCGGCC
GCGCTTGATCGGTTCCTGAC

Downstream 100 bases:

>100_bases
CGCCCCCCTGTCGGGTAAGATGAACGCACAATAATCAAAACCGGGAGCCATCATGTCTGTTCTGGGTTCGCATCATCGAC
TGAAGCGCGACGCGCTGGGC

Product: lipid A biosynthesis acyltransferase

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase HtrB Family; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lauroyl/Myristoyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis Lauroyl Acyltransferase Protein; Lipid A Lauroyl Acyltransferase Protein; Acyltransferase; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSLLHKIETTAARAFLGIFRALGPRAASNLAGALGRGIGPLIPTSRVADQNLRRAMPELDEAARRRIIREVWESLARTAG
EFPHLAALRETDAGPGYEIVGREHCLALAAQGGPALIFTAHFGNWELIPPVLHRLGVRLAFFYRAAANPAVDRLILDLRE
QATGEPVTMFAKGAAGARGSYAHLVRGGILGMLMDQKLNDGIASPLFGIDAMTAPALAVFARKFRCPILPVRAERIGPAR
IRIVFEKLHRIEVTDDREADIAAGTAWMNATIERWVRQRPGQWLWLHRRWPKPVA

Sequences:

>Translated_295_residues
MSLLHKIETTAARAFLGIFRALGPRAASNLAGALGRGIGPLIPTSRVADQNLRRAMPELDEAARRRIIREVWESLARTAG
EFPHLAALRETDAGPGYEIVGREHCLALAAQGGPALIFTAHFGNWELIPPVLHRLGVRLAFFYRAAANPAVDRLILDLRE
QATGEPVTMFAKGAAGARGSYAHLVRGGILGMLMDQKLNDGIASPLFGIDAMTAPALAVFARKFRCPILPVRAERIGPAR
IRIVFEKLHRIEVTDDREADIAAGTAWMNATIERWVRQRPGQWLWLHRRWPKPVA
>Mature_294_residues
SLLHKIETTAARAFLGIFRALGPRAASNLAGALGRGIGPLIPTSRVADQNLRRAMPELDEAARRRIIREVWESLARTAGE
FPHLAALRETDAGPGYEIVGREHCLALAAQGGPALIFTAHFGNWELIPPVLHRLGVRLAFFYRAAANPAVDRLILDLREQ
ATGEPVTMFAKGAAGARGSYAHLVRGGILGMLMDQKLNDGIASPLFGIDAMTAPALAVFARKFRCPILPVRAERIGPARI
RIVFEKLHRIEVTDDREADIAAGTAWMNATIERWVRQRPGQWLWLHRRWPKPVA

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 32470; Mature: 32339

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLHKIETTAARAFLGIFRALGPRAASNLAGALGRGIGPLIPTSRVADQNLRRAMPELD
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHH
EAARRRIIREVWESLARTAGEFPHLAALRETDAGPGYEIVGREHCLALAAQGGPALIFTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCHHHHHEEEECCCCEEEEEE
HFGNWELIPPVLHRLGVRLAFFYRAAANPAVDRLILDLREQATGEPVTMFAKGAAGARGS
ECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
YAHLVRGGILGMLMDQKLNDGIASPLFGIDAMTAPALAVFARKFRCPILPVRAERIGPAR
HHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHH
IRIVFEKLHRIEVTDDREADIAAGTAWMNATIERWVRQRPGQWLWLHRRWPKPVA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
SLLHKIETTAARAFLGIFRALGPRAASNLAGALGRGIGPLIPTSRVADQNLRRAMPELD
CHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHH
EAARRRIIREVWESLARTAGEFPHLAALRETDAGPGYEIVGREHCLALAAQGGPALIFTA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEECCHHHHHEEEECCCCEEEEEE
HFGNWELIPPVLHRLGVRLAFFYRAAANPAVDRLILDLREQATGEPVTMFAKGAAGARGS
ECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
YAHLVRGGILGMLMDQKLNDGIASPLFGIDAMTAPALAVFARKFRCPILPVRAERIGPAR
HHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHH
IRIVFEKLHRIEVTDDREADIAAGTAWMNATIERWVRQRPGQWLWLHRRWPKPVA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA