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The map label for this gene is menA [H]

Identifier: 148259360

GI number: 148259360

Start: 389670

End: 391208

Strand: Reverse

Name: menA [H]

Synonym: Acry_0341

Alternate gene names: 148259360

Gene position: 391208-389670 (Counterclockwise)

Preceding gene: 148259361

Following gene: 148259357

Centisome position: 11.54

GC content: 72.64

Gene sequence:

>1539_bases
ATGGACCAGTTCGGCGCCATGCGCCTCGGCGGCAACGCGGAGCGGGCGAGTGCGGACCAGGCGCTGACCGCGCAACTGTT
CGACAAGGCGCGGCGGATGGTGATCGCCGGCGCGATCGACGGCAACCCGTCGGCAACACCGCTGCTCTGCGCGCGGGATG
GGGAGGACCTCGTCTTCGCCGCCCATCGCGCCTCGCGCCTTGCCGCCCTGCTGTCGATCAATCCGCGGGCGCAGGCGATC
GTCGAGACTGACGATCCGTTATTTTCGCTCCTGCTGGAGGTCACGGGCTTCTGCGTCGAGCTGCGGGAGGCGGCGGCGCG
GGGGCGGGTGTTGGCGGCACTGCATGGCGGGGCCGGGCCGGATGACGCGGCGGCGCGAGAATTTGCCTGCTACCGGCTGC
GGCCGACGCGGCTCGCGCTGGTGGACCGGATGGCGACGCCGCGCTTCGCCTGGCAGGCGCTGCCGCAGAACCGGCGCAGC
GACGCGCGGCTGGCGCTGGACGATCTCGGCGGGTGGATGCGGCTGTGGATCCGCACCGTGCGGGCACCGTTCTTCACCGC
CGCGATCGTGCCGGTGCTGCTGGGCGGGGCGGTGGCGCGGTTCGCGATGGCACGGGCCGGGACCGGGGCGGACTGGCCGT
GGGCGCTGTTCCTCTGGTGCATCGCGGGCGTTCTGCTGGCGGCGGCGGGGACGAACCTGATCAACGATTACGGCGACCAC
GAGACCGGGGCCGACGAGGGCAACGAGGTTGGCGGCAATCCGTTCACCGGGGGCAGCCGGGCGATCCAGCTCGGGATGGT
GGCGGCGTGGAAAGTGCTGCTGGGCAGCGCGATCTGCTTCGGCGGCACGGTCGCGATCGGGCTGCACATCAACGCGGCAC
TCGCCGGCCACGCGCTGGCGCCGACGCCGCTGCTCGGCTTCGGCGTGATCGGCTGCGCACTCGGCATCATGTATACCATG
GGGCCGTTCCGGCTGAGCTATCGCGGGCTCGGCGAGGTCGCGGTGCCGCTCGGCTTCGGGCCGGTGATCGTGCTCGGCAC
CGCCTATGTGCTGGCGAAGGCGATGCACGTGCCGGTGCCCTGGCTGGCGGGGCTGCTGGCCGCCCTGCCGGTTTCGGTGT
TCGTGCTGCTGATCCTGTGGATCAACCAGTTCCAGGACGCGCCGGCCGATGCGGCGGCGGGCAAGCGGACCTGGGTGGTG
CGGCTGGCGGAGACGGCGGGCGGCGACATCGATTTCCGGCGGCCGTTCCGCGCCTATCTGGCGCTGGATGCCGCGGGGTT
CGGGCTGATCGCGCTGCTCGGGCTGATCGGGCGGGCCGATCCGGCGCTGGCGACACGATATGCGTTCCTCGCGCTGCTGC
CGCTGCCGCTCGCCCTCGTCGCTGCGCGCAAGGGGAGCTTGTGGGTGCGGCGCTGGCGGGCGGCGCCGGGCGAGCGGGCG
CGGTTGCCGTTCGAGCTGCTCGGGGTGAACGCGATCACCATCGGCGTGCACCTGGCGACGGGGCTGCTGCTGGCGCTCGC
CTATCTTCTCGCGGGGTGA

Upstream 100 bases:

>100_bases
CGCGCCGCAGGCGGCACCGAAGGCGCCGGCCGGAACGGCGCCGGTCAATCTGAACGGCATGTGCGGCTGAGCGCGGAATT
CGGGACGACGGGAGGCCGGG

Downstream 100 bases:

>100_bases
GCGGCGCGGCCCCTCGCCTCCCGCTCGAACGCCGCGACCACCCGCCAGAGCAGCACCGGCACGAGGCGCGATGCCATCGC
ATCGAGCGGGCGGGAGTCGA

Product: UbiA prenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MDQFGAMRLGGNAERASADQALTAQLFDKARRMVIAGAIDGNPSATPLLCARDGEDLVFAAHRASRLAALLSINPRAQAI
VETDDPLFSLLLEVTGFCVELREAAARGRVLAALHGGAGPDDAAAREFACYRLRPTRLALVDRMATPRFAWQALPQNRRS
DARLALDDLGGWMRLWIRTVRAPFFTAAIVPVLLGGAVARFAMARAGTGADWPWALFLWCIAGVLLAAAGTNLINDYGDH
ETGADEGNEVGGNPFTGGSRAIQLGMVAAWKVLLGSAICFGGTVAIGLHINAALAGHALAPTPLLGFGVIGCALGIMYTM
GPFRLSYRGLGEVAVPLGFGPVIVLGTAYVLAKAMHVPVPWLAGLLAALPVSVFVLLILWINQFQDAPADAAAGKRTWVV
RLAETAGGDIDFRRPFRAYLALDAAGFGLIALLGLIGRADPALATRYAFLALLPLPLALVAARKGSLWVRRWRAAPGERA
RLPFELLGVNAITIGVHLATGLLLALAYLLAG

Sequences:

>Translated_512_residues
MDQFGAMRLGGNAERASADQALTAQLFDKARRMVIAGAIDGNPSATPLLCARDGEDLVFAAHRASRLAALLSINPRAQAI
VETDDPLFSLLLEVTGFCVELREAAARGRVLAALHGGAGPDDAAAREFACYRLRPTRLALVDRMATPRFAWQALPQNRRS
DARLALDDLGGWMRLWIRTVRAPFFTAAIVPVLLGGAVARFAMARAGTGADWPWALFLWCIAGVLLAAAGTNLINDYGDH
ETGADEGNEVGGNPFTGGSRAIQLGMVAAWKVLLGSAICFGGTVAIGLHINAALAGHALAPTPLLGFGVIGCALGIMYTM
GPFRLSYRGLGEVAVPLGFGPVIVLGTAYVLAKAMHVPVPWLAGLLAALPVSVFVLLILWINQFQDAPADAAAGKRTWVV
RLAETAGGDIDFRRPFRAYLALDAAGFGLIALLGLIGRADPALATRYAFLALLPLPLALVAARKGSLWVRRWRAAPGERA
RLPFELLGVNAITIGVHLATGLLLALAYLLAG
>Mature_512_residues
MDQFGAMRLGGNAERASADQALTAQLFDKARRMVIAGAIDGNPSATPLLCARDGEDLVFAAHRASRLAALLSINPRAQAI
VETDDPLFSLLLEVTGFCVELREAAARGRVLAALHGGAGPDDAAAREFACYRLRPTRLALVDRMATPRFAWQALPQNRRS
DARLALDDLGGWMRLWIRTVRAPFFTAAIVPVLLGGAVARFAMARAGTGADWPWALFLWCIAGVLLAAAGTNLINDYGDH
ETGADEGNEVGGNPFTGGSRAIQLGMVAAWKVLLGSAICFGGTVAIGLHINAALAGHALAPTPLLGFGVIGCALGIMYTM
GPFRLSYRGLGEVAVPLGFGPVIVLGTAYVLAKAMHVPVPWLAGLLAALPVSVFVLLILWINQFQDAPADAAAGKRTWVV
RLAETAGGDIDFRRPFRAYLALDAAGFGLIALLGLIGRADPALATRYAFLALLPLPLALVAARKGSLWVRRWRAAPGERA
RLPFELLGVNAITIGVHLATGLLLALAYLLAG

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Escherichia coli, GI1790365, Length=273, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 53982; Mature: 53982

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQFGAMRLGGNAERASADQALTAQLFDKARRMVIAGAIDGNPSATPLLCARDGEDLVFA
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEECCCCCEEEE
AHRASRLAALLSINPRAQAIVETDDPLFSLLLEVTGFCVELREAAARGRVLAALHGGAGP
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
DDAAAREFACYRLRPTRLALVDRMATPRFAWQALPQNRRSDARLALDDLGGWMRLWIRTV
CHHHHHHHHHEECCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHH
RAPFFTAAIVPVLLGGAVARFAMARAGTGADWPWALFLWCIAGVLLAAAGTNLINDYGDH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
ETGADEGNEVGGNPFTGGSRAIQLGMVAAWKVLLGSAICFGGTVAIGLHINAALAGHALA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHCCCCC
PTPLLGFGVIGCALGIMYTMGPFRLSYRGLGEVAVPLGFGPVIVLGTAYVLAKAMHVPVP
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHH
WLAGLLAALPVSVFVLLILWINQFQDAPADAAAGKRTWVVRLAETAGGDIDFRRPFRAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHH
ALDAAGFGLIALLGLIGRADPALATRYAFLALLPLPLALVAARKGSLWVRRWRAAPGERA
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
RLPFELLGVNAITIGVHLATGLLLALAYLLAG
CCCHHHHCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQFGAMRLGGNAERASADQALTAQLFDKARRMVIAGAIDGNPSATPLLCARDGEDLVFA
CCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEECCCCCEEEE
AHRASRLAALLSINPRAQAIVETDDPLFSLLLEVTGFCVELREAAARGRVLAALHGGAGP
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
DDAAAREFACYRLRPTRLALVDRMATPRFAWQALPQNRRSDARLALDDLGGWMRLWIRTV
CHHHHHHHHHEECCCHHHHHHHHHCCCHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHH
RAPFFTAAIVPVLLGGAVARFAMARAGTGADWPWALFLWCIAGVLLAAAGTNLINDYGDH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCC
ETGADEGNEVGGNPFTGGSRAIQLGMVAAWKVLLGSAICFGGTVAIGLHINAALAGHALA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHCCCCC
PTPLLGFGVIGCALGIMYTMGPFRLSYRGLGEVAVPLGFGPVIVLGTAYVLAKAMHVPVP
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCHH
WLAGLLAALPVSVFVLLILWINQFQDAPADAAAGKRTWVVRLAETAGGDIDFRRPFRAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHH
ALDAAGFGLIALLGLIGRADPALATRYAFLALLPLPLALVAARKGSLWVRRWRAAPGERA
HHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
RLPFELLGVNAITIGVHLATGLLLALAYLLAG
CCCHHHHCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]