Click here to switch to the map view.

The map label for this gene is flbA [H]

Identifier: 148259277

GI number: 148259277

Start: 296074

End: 297447

Strand: Reverse

Name: flbA [H]

Synonym: Acry_0257

Alternate gene names: 148259277

Gene position: 297447-296074 (Counterclockwise)

Preceding gene: 148259278

Following gene: 148259276

Centisome position: 8.78

GC content: 70.31

Gene sequence:

>1374_bases
ATGAGCGCCGCGCCGCAACCGACGGCGAAGATCACGGTCGGCGAGGTGCTGGCCGAGATCACCGCGCTCGAACGGGACGG
CAGGCTGGAGGACGCCGAATCGCTCGCCGAGCGCGCGGTCGCCGCCTCGCCCGGGCATCCGCACATCCTGCATCTCTCGG
GGATCGTCGCCTACCGGCGCGGCAACATCCCGCGCGCGATCGAGCGGATCGAGAAATCCCTCGTCCTGGCGCCGGAGGTC
GCGATCTATCCGCGCAACGCCTGCGAGATCTATCGCGGCGCCGGGCGGCTCGACGACGCGCTGGCGATGGCGTTGCGCGC
CGTCGAACTCGCGCCGGAGGAGCGCGCCGCGCATTTCAATCTCGCCCTGATCCGCTACGAGCGCCACGAGCTGGACGCGG
GCATCGAGGCGGCCGACCGCGCCATCGCGCTTTCACCTGATTTCGCCGAGGCGCATTTCGAGCGCGCCGAGCTGCTGCTG
ATCGGCGGAAGGCTGACGGAAGGCTGGGAGAGCTACGAATGGCGCTTCAAGCTGAAGCAGGCCGACGGCATGCTGCCGAA
GACCGACAAGCCGCAATGGGACGGCAGCCCGATGCCGGAGGGGCGGCTGCTGCTGGTCGCCGACCAGGGCTTCGGGGACT
GCATCCAGTTCGGCCGCTATATCCCCTGGGTCGCGGCGCGCGCGCCGAAGCCGGTGATCGCCTGTGGCGGTGATCTCATG
CCGCTGCTGCGGCAGTTCCCTGAGGTGGGCCGGTTCGCGAACAGCTGGGCCGCCGCCGGCGAGTATGACGCCTTCATGCC
GCTCTCCGGGCTGCCGCGCCTCGCCGGCACGACGATCGCGACGATTCCGGCGGACATCCCCTATCTGCGGGCCGATCCAC
GCAAGGTGGAGGCGTGGCGCCAGCGCCTCGCCGCGCTGGTGCCGCCGGGGCTGAAGCGCATCGGCCTGGTCTGGGCCGGG
CGGCCGACCCACAAGAACGACCGCAAGCGCACGGTGCGGCTGGAGCGTTTCGCGCCGCTGTTCGCGCGGCCGGACATCGC
GATCGTCACCGTGCAGAAAGGCGACCGGATCGACGAGGTGGGCGGGTATTTCGGCCCGGCGCCGCTGGTCAATCTCGGGC
CGTCGATCTTCGATTTCACCGATACGCTGGCGATCCTGCAATGCCTCGACCGGCTGGTGACGATCGACACCTCCGTCGCT
CATCTGGCCGGCGCCTCGGGCGTGCCGACCTCGATCATCCTGCCCTATGCGCCCGACTGGCGCTGGCTGCTGGACCGCGA
GGACACGCCCTGGTACCCGTCGCTGCGCCTGTTCCGCCAGGAGCACCCCTCCGACTGGTCCGGCGTCGTCGAACGGGTTG
CCGGGAGTCTCTGA

Upstream 100 bases:

>100_bases
TCCGCCACCGCCGCTTCGGCGACGTCTTCGGCGAGGCGATGCCGGTTCTCGCCCCCTGGATCGAGCGCCTCGGCTATGCC
GCCACGCCGGAGGGCGCGGC

Downstream 100 bases:

>100_bases
TGCGCCGTCTCGCTTCGCTTGTTCTCGCCTGCCTGTTCGGCATGCCCTTCGCCGCGCACGCCGCATCGCTCACGCTGTAT
TCGCGGCTTGATTATGCGCC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSAAPQPTAKITVGEVLAEITALERDGRLEDAESLAERAVAASPGHPHILHLSGIVAYRRGNIPRAIERIEKSLVLAPEV
AIYPRNACEIYRGAGRLDDALAMALRAVELAPEERAAHFNLALIRYERHELDAGIEAADRAIALSPDFAEAHFERAELLL
IGGRLTEGWESYEWRFKLKQADGMLPKTDKPQWDGSPMPEGRLLLVADQGFGDCIQFGRYIPWVAARAPKPVIACGGDLM
PLLRQFPEVGRFANSWAAAGEYDAFMPLSGLPRLAGTTIATIPADIPYLRADPRKVEAWRQRLAALVPPGLKRIGLVWAG
RPTHKNDRKRTVRLERFAPLFARPDIAIVTVQKGDRIDEVGGYFGPAPLVNLGPSIFDFTDTLAILQCLDRLVTIDTSVA
HLAGASGVPTSIILPYAPDWRWLLDREDTPWYPSLRLFRQEHPSDWSGVVERVAGSL

Sequences:

>Translated_457_residues
MSAAPQPTAKITVGEVLAEITALERDGRLEDAESLAERAVAASPGHPHILHLSGIVAYRRGNIPRAIERIEKSLVLAPEV
AIYPRNACEIYRGAGRLDDALAMALRAVELAPEERAAHFNLALIRYERHELDAGIEAADRAIALSPDFAEAHFERAELLL
IGGRLTEGWESYEWRFKLKQADGMLPKTDKPQWDGSPMPEGRLLLVADQGFGDCIQFGRYIPWVAARAPKPVIACGGDLM
PLLRQFPEVGRFANSWAAAGEYDAFMPLSGLPRLAGTTIATIPADIPYLRADPRKVEAWRQRLAALVPPGLKRIGLVWAG
RPTHKNDRKRTVRLERFAPLFARPDIAIVTVQKGDRIDEVGGYFGPAPLVNLGPSIFDFTDTLAILQCLDRLVTIDTSVA
HLAGASGVPTSIILPYAPDWRWLLDREDTPWYPSLRLFRQEHPSDWSGVVERVAGSL
>Mature_456_residues
SAAPQPTAKITVGEVLAEITALERDGRLEDAESLAERAVAASPGHPHILHLSGIVAYRRGNIPRAIERIEKSLVLAPEVA
IYPRNACEIYRGAGRLDDALAMALRAVELAPEERAAHFNLALIRYERHELDAGIEAADRAIALSPDFAEAHFERAELLLI
GGRLTEGWESYEWRFKLKQADGMLPKTDKPQWDGSPMPEGRLLLVADQGFGDCIQFGRYIPWVAARAPKPVIACGGDLMP
LLRQFPEVGRFANSWAAAGEYDAFMPLSGLPRLAGTTIATIPADIPYLRADPRKVEAWRQRLAALVPPGLKRIGLVWAGR
PTHKNDRKRTVRLERFAPLFARPDIAIVTVQKGDRIDEVGGYFGPAPLVNLGPSIFDFTDTLAILQCLDRLVTIDTSVAH
LAGASGVPTSIILPYAPDWRWLLDREDTPWYPSLRLFRQEHPSDWSGVVERVAGSL

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=152, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI32307148, Length=152, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=159, Percent_Identity=28.9308176100629, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=159, Percent_Identity=28.9308176100629, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647755, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585827, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585829, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50422; Mature: 50291

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPQPTAKITVGEVLAEITALERDGRLEDAESLAERAVAASPGHPHILHLSGIVAYRR
CCCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEECC
GNIPRAIERIEKSLVLAPEVAIYPRNACEIYRGAGRLDDALAMALRAVELAPEERAAHFN
CCCHHHHHHHHHHEEECCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCEEE
LALIRYERHELDAGIEAADRAIALSPDFAEAHFERAELLLIGGRLTEGWESYEWRFKLKQ
EEEEEEEHHHHCCCHHHHCCEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCEEEEEEEC
ADGMLPKTDKPQWDGSPMPEGRLLLVADQGFGDCIQFGRYIPWVAARAPKPVIACGGDLM
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCHHHHCCCCCEEEECCHHH
PLLRQFPEVGRFANSWAAAGEYDAFMPLSGLPRLAGTTIATIPADIPYLRADPRKVEAWR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHH
QRLAALVPPGLKRIGLVWAGRPTHKNDRKRTVRLERFAPLFARPDIAIVTVQKGDRIDEV
HHHHHHCCCCHHHEEEEECCCCCCCCCHHHEEEHHHHCHHHCCCCEEEEEECCCCCHHHH
GGYFGPAPLVNLGPSIFDFTDTLAILQCLDRLVTIDTSVAHLAGASGVPTSIILPYAPDW
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCCC
RWLLDREDTPWYPSLRLFRQEHPSDWSGVVERVAGSL
EEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SAAPQPTAKITVGEVLAEITALERDGRLEDAESLAERAVAASPGHPHILHLSGIVAYRR
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEECC
GNIPRAIERIEKSLVLAPEVAIYPRNACEIYRGAGRLDDALAMALRAVELAPEERAAHFN
CCCHHHHHHHHHHEEECCCEEECCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCEEE
LALIRYERHELDAGIEAADRAIALSPDFAEAHFERAELLLIGGRLTEGWESYEWRFKLKQ
EEEEEEEHHHHCCCHHHHCCEEEECCCHHHHHHCCEEEEEECCCCCCCCCCCEEEEEEEC
ADGMLPKTDKPQWDGSPMPEGRLLLVADQGFGDCIQFGRYIPWVAARAPKPVIACGGDLM
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCHHHHCCCCCEEEECCHHH
PLLRQFPEVGRFANSWAAAGEYDAFMPLSGLPRLAGTTIATIPADIPYLRADPRKVEAWR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHH
QRLAALVPPGLKRIGLVWAGRPTHKNDRKRTVRLERFAPLFARPDIAIVTVQKGDRIDEV
HHHHHHCCCCHHHEEEEECCCCCCCCCHHHEEEHHHHCHHHCCCCEEEEEECCCCCHHHH
GGYFGPAPLVNLGPSIFDFTDTLAILQCLDRLVTIDTSVAHLAGASGVPTSIILPYAPDW
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEECCCCC
RWLLDREDTPWYPSLRLFRQEHPSDWSGVVERVAGSL
EEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748431; 11259647; 1699845 [H]