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The map label for this gene is 148259147

Identifier: 148259147

GI number: 148259147

Start: 139350

End: 140063

Strand: Reverse

Name: 148259147

Synonym: Acry_0127

Alternate gene names: NA

Gene position: 140063-139350 (Counterclockwise)

Preceding gene: 148259148

Following gene: 148259146

Centisome position: 4.13

GC content: 70.87

Gene sequence:

>714_bases
TTGACTGACCCCGGTGCGACAGAGCCGCTCACCGTCCTGGTGACGCGCCCCGAACCGGGCGGCAGCGCCACCGCCGCCGC
CCTCCGCGCGGCAGGATATGTGCCGGTTCTCGCACCCTGTCTTGAGATCGAACCATTGCCGGGGGCTTTGCCAACGCTGG
TGGATGGAATCGTGATCGCCAGCACCCAGGCGCTGCCCGGCCTGCCACCGGCACTGCGGGCCGTGCCGCTGTTCGCGGTG
GGTGATGCCACCGCCGCCCGCGCGCGGGCAGCCGGGTTCATCGACGTCGCGAGCGCCGCCGGAACGGCACGGGAACTGGC
GGCGCTGTTGGGTGAGCGGCTCGATCCCGGCGCACGGCTGCTGCTGGCCTGTGGTGCGGGGCACAGTATGGATCTCGCTG
CTGATCTTCGCGGCCGCGGCTTCCGGGTGACACGTCGGGTGGTATACCGCTCGCGCCCGGCCCGGCAGCTCGACGCGGCA
GCCCAGGCGGCGCTGGAGGCAGGCGAAATCGACCGGGTGATGGTATTCTCACCAGCCAGTGCGCGGCGTTTCGTGACCCT
CATCACTGAGGCGGGGCTCGACGGGGCGCTGGCCGGGGCGATTGCCGTGGCAATCAGCCCGGCGGCTGCGGCCCCGCTCA
CGCGCCTGCCCTTCCGCGACATCCGCAGCGCGGTTTCGCCCGATCAGGATCACATGATAACGATACTGGCATGA

Upstream 100 bases:

>100_bases
CTGCTGAAGCGCAGCGAGGTGGCGAACGCCGCCGATGCGGTGCGACTGGGGGCGGAACTCGGTGCCTCGCTGCGGCGCGA
CAGCCCGGCCGACATCTTTC

Downstream 100 bases:

>100_bases
CCGAGCACGACCCGAACCAGACCCCGACCGCTCCCTCCGCCACCGGCGAACCGGCGCTAGCCGCCGCGCCAGAGCCTCAG
GCTGCCGACCCCGCGACCGC

Product: uroporphyrinogen III synthase HEM4

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTDPGATEPLTVLVTRPEPGGSATAAALRAAGYVPVLAPCLEIEPLPGALPTLVDGIVIASTQALPGLPPALRAVPLFAV
GDATAARARAAGFIDVASAAGTARELAALLGERLDPGARLLLACGAGHSMDLAADLRGRGFRVTRRVVYRSRPARQLDAA
AQAALEAGEIDRVMVFSPASARRFVTLITEAGLDGALAGAIAVAISPAAAAPLTRLPFRDIRSAVSPDQDHMITILA

Sequences:

>Translated_237_residues
MTDPGATEPLTVLVTRPEPGGSATAAALRAAGYVPVLAPCLEIEPLPGALPTLVDGIVIASTQALPGLPPALRAVPLFAV
GDATAARARAAGFIDVASAAGTARELAALLGERLDPGARLLLACGAGHSMDLAADLRGRGFRVTRRVVYRSRPARQLDAA
AQAALEAGEIDRVMVFSPASARRFVTLITEAGLDGALAGAIAVAISPAAAAPLTRLPFRDIRSAVSPDQDHMITILA
>Mature_236_residues
TDPGATEPLTVLVTRPEPGGSATAAALRAAGYVPVLAPCLEIEPLPGALPTLVDGIVIASTQALPGLPPALRAVPLFAVG
DATAARARAAGFIDVASAAGTARELAALLGERLDPGARLLLACGAGHSMDLAADLRGRGFRVTRRVVYRSRPARQLDAAA
QAALEAGEIDRVMVFSPASARRFVTLITEAGLDGALAGAIAVAISPAAAAPLTRLPFRDIRSAVSPDQDHMITILA

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 24117; Mature: 23986

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPGATEPLTVLVTRPEPGGSATAAALRAAGYVPVLAPCLEIEPLPGALPTLVDGIVIA
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHCCHHEE
STQALPGLPPALRAVPLFAVGDATAARARAAGFIDVASAAGTARELAALLGERLDPGARL
CCCCCCCCCHHHHHCEEEEECCCHHHHHHHCCCEEHHHHCCCHHHHHHHHHCCCCCCCEE
LLACGAGHSMDLAADLRGRGFRVTRRVVYRSRPARQLDAAAQAALEAGEIDRVMVFSPAS
EEEECCCCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
ARRFVTLITEAGLDGALAGAIAVAISPAAAAPLTRLPFRDIRSAVSPDQDHMITILA
HHHHHHEEHHCCCCHHHHHHHHHEECCHHCCCCCCCCHHHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure 
TDPGATEPLTVLVTRPEPGGSATAAALRAAGYVPVLAPCLEIEPLPGALPTLVDGIVIA
CCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHCCHHEE
STQALPGLPPALRAVPLFAVGDATAARARAAGFIDVASAAGTARELAALLGERLDPGARL
CCCCCCCCCHHHHHCEEEEECCCHHHHHHHCCCEEHHHHCCCHHHHHHHHHCCCCCCCEE
LLACGAGHSMDLAADLRGRGFRVTRRVVYRSRPARQLDAAAQAALEAGEIDRVMVFSPAS
EEEECCCCCCCCHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
ARRFVTLITEAGLDGALAGAIAVAISPAAAAPLTRLPFRDIRSAVSPDQDHMITILA
HHHHHHEEHHCCCCHHHHHHHHHEECCHHCCCCCCCCHHHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA