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The map label for this gene is trpB [H]

Identifier: 148243370

GI number: 148243370

Start: 1973782

End: 1975050

Strand: Direct

Name: trpB [H]

Synonym: SynRCC307_2271

Alternate gene names: 148243370

Gene position: 1973782-1975050 (Clockwise)

Preceding gene: 148243369

Following gene: 148243373

Centisome position: 88.71

GC content: 65.33

Gene sequence:

>1269_bases
TTGATTGCGCCGGTGACCAGCACGCTGCCCAACTCCGCGGCCCTGGATGCCGCCTCTCGCCCTAACGGTTTGGGCCGCTT
CGGCCGTTTTGGCGGTCAATACGTTCCTGAAACGCTGATGCCAGCGCTGGCTGAGCTGGAAGCCGCCGCCGCTGAAGCCT
GGCAAGACAAGGCCTTCACCGATCGCTTAAACGCGCTGCTGCGCGATTACGTGGGCCGGCCCAGCCCCCTCTATGAGGCC
GAGCGCCTCAGCGAGCACTACCGCCGCGCTGAAGGCGGACCCCGCATTTGGCTCAAGCGCGAGGACCTCAACCACACCGG
CGCCCACAAGATCAACAACGCCCTTGGCCAAGCGCTGCTGGCGCTACGCATGGGCAAAAAGCGGATCATTGCTGAAACCG
GTGCTGGCCAGCACGGCGTGGCCACCGCGACCGTCTGCGCCCGCTTCGGCCTGGAGTGTGTCATCTACATGGGCGCGGAA
GACATGCGTCGTCAGGCCCTCAACGTCTTCCGCATGCGTCTGTTGGGCGCCACCGTTCAACCGGTGACAGCGGGCACCGC
CACCTTGAAAGACGCCACCAGCGAAGCCATCCGCGATTGGGTGACCAACGTTGAGAGCACCCACTACATCCTTGGCTCGG
TGGCTGGCCCGCATCCCTACCCGATGCTGGTGCGCGACTTCCACGCCTGCATTGGCCGGGAAACCCGCCAGCAGTGCCAC
GACGCCTTTGGCCGGCTTCCTGATGTGTTGTTGGCCTGCGTGGGTGGCGGTTCCAATGCCATGGGGCTCTTCCACCCCTT
CGTAGCCGACACCAGCGTTCGCCTCATCGGCGTTGAAGCCGCCGGTGAAGGGGTCGCCAGTGGTCGCCATGCCGCCACGA
TCACCGAAGGGCGCACCGGCGTTCTGCATGGGGCCATGAGCCTGCTGCTGCAGGACGGCGATGGCCAGGTGATGGAGGCC
CACTCCATCAGCGCTGGCCTTGATTACCCCGGCGTTGGGCCTGAGCACAGCTACCTGCGAGAGATCGGGCGCGCCGAGTA
CGCCGCGGTAACCGACACGCAAGCCCTCGATGCCCTGCAGCGCCTCAGCCAACTGGAAGGGATCATCCCGGCCCTGGAAA
CTGCCCATGCCTTTGCTTGGCTCGAAAGCCTCTGCCCAACTCTGGCTCCAGGCACTGAGGTGGTGATCAACCTCTCCGGC
CGCGGGGACAAAGACGTGAACACCGTGGCCGAGCGCCTCGGCGATCAACTCAAGCCAGCAGACGGCTGA

Upstream 100 bases:

>100_bases
CAGCGCCAACCGCTGCCGGGGGGAGCAGGGCCGCATCCAAATCCTTGAGCCCTACGGCTGGCCTCCCATAGCCCCACCGG
CTCCCTAGGCTGACGCCAAC

Downstream 100 bases:

>100_bases
GGGTTCCAGCCACCGCCTCAACGGCGGCCAAGGCCGTGGCATAGGCCATCCGCATCGGCCCCACCAACGCCACGCTGCCC
TCACCACCGGAAGCGGTGGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MIAPVTSTLPNSAALDAASRPNGLGRFGRFGGQYVPETLMPALAELEAAAAEAWQDKAFTDRLNALLRDYVGRPSPLYEA
ERLSEHYRRAEGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAE
DMRRQALNVFRMRLLGATVQPVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHACIGRETRQQCH
DAFGRLPDVLLACVGGGSNAMGLFHPFVADTSVRLIGVEAAGEGVASGRHAATITEGRTGVLHGAMSLLLQDGDGQVMEA
HSISAGLDYPGVGPEHSYLREIGRAEYAAVTDTQALDALQRLSQLEGIIPALETAHAFAWLESLCPTLAPGTEVVINLSG
RGDKDVNTVAERLGDQLKPADG

Sequences:

>Translated_422_residues
MIAPVTSTLPNSAALDAASRPNGLGRFGRFGGQYVPETLMPALAELEAAAAEAWQDKAFTDRLNALLRDYVGRPSPLYEA
ERLSEHYRRAEGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAE
DMRRQALNVFRMRLLGATVQPVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHACIGRETRQQCH
DAFGRLPDVLLACVGGGSNAMGLFHPFVADTSVRLIGVEAAGEGVASGRHAATITEGRTGVLHGAMSLLLQDGDGQVMEA
HSISAGLDYPGVGPEHSYLREIGRAEYAAVTDTQALDALQRLSQLEGIIPALETAHAFAWLESLCPTLAPGTEVVINLSG
RGDKDVNTVAERLGDQLKPADG
>Mature_422_residues
MIAPVTSTLPNSAALDAASRPNGLGRFGRFGGQYVPETLMPALAELEAAAAEAWQDKAFTDRLNALLRDYVGRPSPLYEA
ERLSEHYRRAEGGPRIWLKREDLNHTGAHKINNALGQALLALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAE
DMRRQALNVFRMRLLGATVQPVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHACIGRETRQQCH
DAFGRLPDVLLACVGGGSNAMGLFHPFVADTSVRLIGVEAAGEGVASGRHAATITEGRTGVLHGAMSLLLQDGDGQVMEA
HSISAGLDYPGVGPEHSYLREIGRAEYAAVTDTQALDALQRLSQLEGIIPALETAHAFAWLESLCPTLAPGTEVVINLSG
RGDKDVNTVAERLGDQLKPADG

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=53.6082474226804, Blast_Score=418, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=389, Percent_Identity=61.439588688946, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45058; Mature: 45058

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAPVTSTLPNSAALDAASRPNGLGRFGRFGGQYVPETLMPALAELEAAAAEAWQDKAFT
CCCCCCCCCCCCHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DRLNALLRDYVGRPSPLYEAERLSEHYRRAEGGPRIWLKREDLNHTGAHKINNALGQALL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAEDMRRQALNVFRMRLLGATVQ
HHHHCCHHEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
PVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHACIGRETRQQCH
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHHHHHHHHHHCHHHHHHHH
DAFGRLPDVLLACVGGGSNAMGLFHPFVADTSVRLIGVEAAGEGVASGRHAATITEGRTG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCHH
VLHGAMSLLLQDGDGQVMEAHSISAGLDYPGVGPEHSYLREIGRAEYAAVTDTQALDALQ
HHHHHHHHHHCCCCCCEEEHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
RLSQLEGIIPALETAHAFAWLESLCPTLAPGTEVVINLSGRGDKDVNTVAERLGDQLKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCC
DG
CC
>Mature Secondary Structure
MIAPVTSTLPNSAALDAASRPNGLGRFGRFGGQYVPETLMPALAELEAAAAEAWQDKAFT
CCCCCCCCCCCCHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DRLNALLRDYVGRPSPLYEAERLSEHYRRAEGGPRIWLKREDLNHTGAHKINNALGQALL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ALRMGKKRIIAETGAGQHGVATATVCARFGLECVIYMGAEDMRRQALNVFRMRLLGATVQ
HHHHCCHHEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCC
PVTAGTATLKDATSEAIRDWVTNVESTHYILGSVAGPHPYPMLVRDFHACIGRETRQQCH
CCCCCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCCCCCCHHHHHHHHHHHCHHHHHHHH
DAFGRLPDVLLACVGGGSNAMGLFHPFVADTSVRLIGVEAAGEGVASGRHAATITEGRTG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCHH
VLHGAMSLLLQDGDGQVMEAHSISAGLDYPGVGPEHSYLREIGRAEYAAVTDTQALDALQ
HHHHHHHHHHCCCCCCEEEHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
RLSQLEGIIPALETAHAFAWLESLCPTLAPGTEVVINLSGRGDKDVNTVAERLGDQLKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCC
DG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]