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The map label for this gene is menA [H]

Identifier: 148243352

GI number: 148243352

Start: 1959102

End: 1960037

Strand: Direct

Name: menA [H]

Synonym: SynRCC307_2253

Alternate gene names: 148243352

Gene position: 1959102-1960037 (Clockwise)

Preceding gene: 148243350

Following gene: 148243353

Centisome position: 88.05

GC content: 65.92

Gene sequence:

>936_bases
ATGGCTGAGCCCCAGGTCGTCGCAAGCCGTTACGCGCTCTGGAAGGCGGCCATCAAATGGCCGATGTACTCCGTGGCAGT
GATGCCAGCGCTTTTGGCCAGTGGCTGGCTTCAAAGTCAGGGGTTAGACCCCCGCTGGGGCCAGCTCGGCCTGTTTCTGC
TCGCAGCGGTGCTGCTGCTGGGGTGGGAAAACCTCAGCAACGACGTGTTTGATGACGACACCGGTGTCGACACCCTCGGC
AAACCCCATTCCTTGGTGGCCCTGACCGGCCGCCGCGATCGCATTGCTTGGATTGCTCACAGCCTGCTCGCTGGCGGATT
GCTGCTGATGGCCCTGGTGGCCCTGCGCAGCCAACCGGTGGTGCTGCTGCTAGTGCTGATCTGCTGCGGCCTGGGATACC
TCTACCAAGGCCCACCCTTTCGTTTGGGCTACCGCGGCCTCGGCGAACCGCTGTGCTGGCTGGCCTTTGGCCCCTTCGCC
ACGGCCGCTGCGCTGATGGCGCTGCAGCCACCAACGAGCCTGCCGGCTGCAGTGCCTTGGCAGGTGGCACTGAGCCTGGG
CTCCGGCCCGGCGCTGGCCACCACCTTGGTGTTGTTCTGCTCCCACTTTCATCAGGTCGAGGAGGACGCTGCCCACGGCA
AACGCTCTCCGGTTGTGAAGCTGGGCACGGCCAAAGCCGCGGCCGTGGTGCCCTGGCTTGTGGCGGCAAGCTTGGCCCTG
CAATGGCTGCCGGTGCTGGAGCGCCAGTGGCCCTCCACCGCGCTGCTGAGCGTGATCGGGTTGCCCGCTGCAGCGCAGCT
GATTCGGCTGCTGCGGGAGCATCACCACCAGCCCGAGCGGATTAGCGGCAGCAAGTTTTTGGCCTTGCGCTTTCAAGCCC
TAAGCGGCCTCGGGCTCGCCATCGGCCTGGGCATTGCACCTTGGCTGGGACGTTGA

Upstream 100 bases:

>100_bases
CTGGCTGAGCAAGTCGGTGAAGCGGGGGGCCTGTTGCACCACACAACCGGGGGACTGCTCAAATGTATGGGTCTCTCGTG
GCCCGTAGTGGCGGGCAGCC

Downstream 100 bases:

>100_bases
TGCAACTGCGCTGGCGCCCATACCGGTGGGCGCTGCAGCCGCCTTTGATCACCGCCTGCGGGCCCTGGAGCGAGCGGCGC
GGCTGGCTGCTGCGGCTCGA

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MAEPQVVASRYALWKAAIKWPMYSVAVMPALLASGWLQSQGLDPRWGQLGLFLLAAVLLLGWENLSNDVFDDDTGVDTLG
KPHSLVALTGRRDRIAWIAHSLLAGGLLLMALVALRSQPVVLLLVLICCGLGYLYQGPPFRLGYRGLGEPLCWLAFGPFA
TAAALMALQPPTSLPAAVPWQVALSLGSGPALATTLVLFCSHFHQVEEDAAHGKRSPVVKLGTAKAAAVVPWLVAASLAL
QWLPVLERQWPSTALLSVIGLPAAAQLIRLLREHHHQPERISGSKFLALRFQALSGLGLAIGLGIAPWLGR

Sequences:

>Translated_311_residues
MAEPQVVASRYALWKAAIKWPMYSVAVMPALLASGWLQSQGLDPRWGQLGLFLLAAVLLLGWENLSNDVFDDDTGVDTLG
KPHSLVALTGRRDRIAWIAHSLLAGGLLLMALVALRSQPVVLLLVLICCGLGYLYQGPPFRLGYRGLGEPLCWLAFGPFA
TAAALMALQPPTSLPAAVPWQVALSLGSGPALATTLVLFCSHFHQVEEDAAHGKRSPVVKLGTAKAAAVVPWLVAASLAL
QWLPVLERQWPSTALLSVIGLPAAAQLIRLLREHHHQPERISGSKFLALRFQALSGLGLAIGLGIAPWLGR
>Mature_310_residues
AEPQVVASRYALWKAAIKWPMYSVAVMPALLASGWLQSQGLDPRWGQLGLFLLAAVLLLGWENLSNDVFDDDTGVDTLGK
PHSLVALTGRRDRIAWIAHSLLAGGLLLMALVALRSQPVVLLLVLICCGLGYLYQGPPFRLGYRGLGEPLCWLAFGPFAT
AAALMALQPPTSLPAAVPWQVALSLGSGPALATTLVLFCSHFHQVEEDAAHGKRSPVVKLGTAKAAAVVPWLVAASLALQ
WLPVLERQWPSTALLSVIGLPAAAQLIRLLREHHHQPERISGSKFLALRFQALSGLGLAIGLGIAPWLGR

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011937
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 33289; Mature: 33158

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPQVVASRYALWKAAIKWPMYSVAVMPALLASGWLQSQGLDPRWGQLGLFLLAAVLLL
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GWENLSNDVFDDDTGVDTLGKPHSLVALTGRRDRIAWIAHSLLAGGLLLMALVALRSQPV
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VLLLVLICCGLGYLYQGPPFRLGYRGLGEPLCWLAFGPFATAAALMALQPPTSLPAAVPW
HHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QVALSLGSGPALATTLVLFCSHFHQVEEDAAHGKRSPVVKLGTAKAAAVVPWLVAASLAL
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
QWLPVLERQWPSTALLSVIGLPAAAQLIRLLREHHHQPERISGSKFLALRFQALSGLGLA
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHH
IGLGIAPWLGR
HHHCCHHCCCC
>Mature Secondary Structure 
AEPQVVASRYALWKAAIKWPMYSVAVMPALLASGWLQSQGLDPRWGQLGLFLLAAVLLL
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GWENLSNDVFDDDTGVDTLGKPHSLVALTGRRDRIAWIAHSLLAGGLLLMALVALRSQPV
HHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VLLLVLICCGLGYLYQGPPFRLGYRGLGEPLCWLAFGPFATAAALMALQPPTSLPAAVPW
HHHHHHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QVALSLGSGPALATTLVLFCSHFHQVEEDAAHGKRSPVVKLGTAKAAAVVPWLVAASLAL
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHH
QWLPVLERQWPSTALLSVIGLPAAAQLIRLLREHHHQPERISGSKFLALRFQALSGLGLA
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHH
IGLGIAPWLGR
HHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]