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The map label for this gene is menC [H]

Identifier: 148243353

GI number: 148243353

Start: 1960037

End: 1960993

Strand: Direct

Name: menC [H]

Synonym: SynRCC307_2254

Alternate gene names: 148243353

Gene position: 1960037-1960993 (Clockwise)

Preceding gene: 148243352

Following gene: 148243354

Centisome position: 88.09

GC content: 69.59

Gene sequence:

>957_bases
ATGCAACTGCGCTGGCGCCCATACCGGTGGGCGCTGCAGCCGCCTTTGATCACCGCCTGCGGGCCCTGGAGCGAGCGGCG
CGGCTGGCTGCTGCGGCTCGAGGACCCAGGCAGCGGTTCTGCGGGTTGGGGAGAAGCCGCACCCTTGCCGGCTGAGCACG
CCCAGTGCGCCGATGCACTCGCGGCATTGCCTTCTGAGTGCAGCACCGAGCACCTGGAGCAAGCGCTCAGGGCACTGCCT
GGGCCTGCGGCCTTTGCCATCGGACTGGCCCTAGCCGAGCTGGAAGGGCTCCAAGGCGGGCAATGGCTGCCGGCTCCCGC
TTCAGCGGTGTTGCTGCCAGCCGGCGGTGAGGCCATCGCAGCCCTGAAGAGCGCGCTCCAGCGAGCCACAGGCGAGCCAG
CGGAGTTCGCAGCCAAGTGGAAGGTGGGGGTGCTGGATCCAGACACCGAACTGCAGCTGCTGGAGCAACTTTTGGAGCAA
CTTCCCAGCGGCGCCCAGCTCCGCCTTGATTCCAATGGCAGCTGGGACCGTGCCACCGCGGGGCGCTGGGCCATGCGTTT
GAAGCACGAGGGCAAGCTGCAATGGCTGGAGCAGCCCTTGCCACCCAGCGACCATGCCGGCTTGCTCGCCCTGGGTCGCC
GGCTGCCGGTGGCCCTCGATGAATCGCTCCGGCATCCCAGCGGCCTCCCCCCTGGGTGGAGCGGCTGGCTGGTGCACAAA
CCAGCTCTCGAGGGTGATCCCCGGCCCCTGCTGCTGCAGCTCAAACAAGGGGCCGCCAAACAGATGGTGAGCAGTGCCTT
GGAGAGCGGCATAGGAGCCCGGGCGGTGGCCCACATGGCGGCCCTGGCCAGCCGCGGCCCCACACCATGCGCCGCTGGAC
TGGCCCCGGGCTGGGGTGCTTCTGGCGATCTCGCCAGCACGATCCCCCAGCAGGTGTGGGAGGCCGCCGGCTCATGA

Upstream 100 bases:

>100_bases
AGCGGATTAGCGGCAGCAAGTTTTTGGCCTTGCGCTTTCAAGCCCTAAGCGGCCTCGGGCTCGCCATCGGCCTGGGCATT
GCACCTTGGCTGGGACGTTG

Downstream 100 bases:

>100_bases
ACGGCTGGGAGCTACGGGCCAGTGCGCTTGAAGAGCAAGCGGGCCGCGATGCGATGACCTGCTGCCAACGGTGGCCAGAA
GGCAGCGGCGTGGTGATCGG

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MQLRWRPYRWALQPPLITACGPWSERRGWLLRLEDPGSGSAGWGEAAPLPAEHAQCADALAALPSECSTEHLEQALRALP
GPAAFAIGLALAELEGLQGGQWLPAPASAVLLPAGGEAIAALKSALQRATGEPAEFAAKWKVGVLDPDTELQLLEQLLEQ
LPSGAQLRLDSNGSWDRATAGRWAMRLKHEGKLQWLEQPLPPSDHAGLLALGRRLPVALDESLRHPSGLPPGWSGWLVHK
PALEGDPRPLLLQLKQGAAKQMVSSALESGIGARAVAHMAALASRGPTPCAAGLAPGWGASGDLASTIPQQVWEAAGS

Sequences:

>Translated_318_residues
MQLRWRPYRWALQPPLITACGPWSERRGWLLRLEDPGSGSAGWGEAAPLPAEHAQCADALAALPSECSTEHLEQALRALP
GPAAFAIGLALAELEGLQGGQWLPAPASAVLLPAGGEAIAALKSALQRATGEPAEFAAKWKVGVLDPDTELQLLEQLLEQ
LPSGAQLRLDSNGSWDRATAGRWAMRLKHEGKLQWLEQPLPPSDHAGLLALGRRLPVALDESLRHPSGLPPGWSGWLVHK
PALEGDPRPLLLQLKQGAAKQMVSSALESGIGARAVAHMAALASRGPTPCAAGLAPGWGASGDLASTIPQQVWEAAGS
>Mature_318_residues
MQLRWRPYRWALQPPLITACGPWSERRGWLLRLEDPGSGSAGWGEAAPLPAEHAQCADALAALPSECSTEHLEQALRALP
GPAAFAIGLALAELEGLQGGQWLPAPASAVLLPAGGEAIAALKSALQRATGEPAEFAAKWKVGVLDPDTELQLLEQLLEQ
LPSGAQLRLDSNGSWDRATAGRWAMRLKHEGKLQWLEQPLPPSDHAGLLALGRRLPVALDESLRHPSGLPPGWSGWLVHK
PALEGDPRPLLLQLKQGAAKQMVSSALESGIGARAVAHMAALASRGPTPCAAGLAPGWGASGDLASTIPQQVWEAAGS

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 33457; Mature: 33457

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRWRPYRWALQPPLITACGPWSERRGWLLRLEDPGSGSAGWGEAAPLPAEHAQCADAL
CCCCCCCCCEECCCCEEEECCCCHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
AALPSECSTEHLEQALRALPGPAAFAIGLALAELEGLQGGQWLPAPASAVLLPAGGEAIA
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHH
ALKSALQRATGEPAEFAAKWKVGVLDPDTELQLLEQLLEQLPSGAQLRLDSNGSWDRATA
HHHHHHHHHCCCCHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
GRWAMRLKHEGKLQWLEQPLPPSDHAGLLALGRRLPVALDESLRHPSGLPPGWSGWLVHK
HHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEC
PALEGDPRPLLLQLKQGAAKQMVSSALESGIGARAVAHMAALASRGPTPCAAGLAPGWGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SGDLASTIPQQVWEAAGS
CCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLRWRPYRWALQPPLITACGPWSERRGWLLRLEDPGSGSAGWGEAAPLPAEHAQCADAL
CCCCCCCCCEECCCCEEEECCCCHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHH
AALPSECSTEHLEQALRALPGPAAFAIGLALAELEGLQGGQWLPAPASAVLLPAGGEAIA
HHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHH
ALKSALQRATGEPAEFAAKWKVGVLDPDTELQLLEQLLEQLPSGAQLRLDSNGSWDRATA
HHHHHHHHHCCCCHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
GRWAMRLKHEGKLQWLEQPLPPSDHAGLLALGRRLPVALDESLRHPSGLPPGWSGWLVHK
HHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEC
PALEGDPRPLLLQLKQGAAKQMVSSALESGIGARAVAHMAALASRGPTPCAAGLAPGWGA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
SGDLASTIPQQVWEAAGS
CCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]