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The map label for this gene is fusA [H]

Identifier: 148243268

GI number: 148243268

Start: 1877732

End: 1879807

Strand: Direct

Name: fusA [H]

Synonym: SynRCC307_2169

Alternate gene names: 148243268

Gene position: 1877732-1879807 (Clockwise)

Preceding gene: 148243267

Following gene: 148243269

Centisome position: 84.4

GC content: 56.74

Gene sequence:

>2076_bases
GTGCCTCGCGACTTCCCCCTCGATCGCGTCAGGAATATCGGCATTGCCGCTCATATCGACGCTGGCAAAACCACGACCAC
GGAACGCATCCTGTTTTATTCAGGCGTGGTGCACAAGATTGGCGAGGTCCACGATGGCGCCGCCGTGACTGACTGGATGG
CCCAGGAGCGCGAGCGCGGCATCACCATTACGGCTGCGGCTATTTCCACTGCGTGGAATGACCACCGCATCAACATCATT
GATACCCCCGGTCACGTGGACTTCACCATTGAGGTGGAGCGTTCCATGCGTGTGCTCGATGGCGTGATTGCCGTCTTCTG
CGCCGTGGGTGGTGTTCAACCTCAGTCGGAAACTGTTTGGCGTCAGGCGGATCGTTACAGCGTTCCCCGCATGGTGTTCG
TCAACAAGATGGATCGAACCGGGGCTGACTTCCTCAAGGTCTATGGACAAATCGTTGATCGCCTGAAAGCAAAAGCTGCC
CCCATTCAGCTTCCGATTGGCGCCGAAGGTGACCTGAGCGGAATTATCGATTTGGTGGCCAACAAGGCCTATATCTATAA
GAACGATCTGGGCACAGATATCGAAGAAGCTGAGATTCCTGCCGACATGGCAGACGAAGCAGCTGAATGGCGGGCAAAGC
TCATGGAAAGTGTTGCCGAAAACGACGAAGAACTGATTGAAAAGTTCCTCGAAACCGGTGAACTTACAGAAGCTGAACTC
AAAAAAGGCATCCGTGACGGCGTGTTGAAGCACGGCCTTGTTCCGATGCTCTGCGGTTCTGCTTTCAAGAACAAAGGTGT
GCAGCTGGTGCTCGACGCTGTGGTCGATTACCTGCCCGCTCCCATCGATGTGCCCCCGATCCAGGGTGTGTTGGCCGATG
GCAGCGAAGCCGTTCGTCCTTCTGACGACAATGCTCCCTTTAGTGCACTGGCCTTCAAGGTCATGGCTGACCCCTACGGA
AAGCTCACCTTCGTGCGGATGTATTCCGGCGTGCTCTCCAAGGGCAGCTACGTGATGAATTCGACCAAGGACGTCAAAGA
GCGCATCTCCCGTCTGGTGGTGCTGAAGGCTGACGATCGCGAGGAGGTGGACCAACTGCGCGCTGGTGACCTGGGCGCGG
TGCTGGGCCTGAAGAACACCACCACCGGTGACACCCTCTGCGATCCCGACAACAGCATCGTTCTGGAGACCCTGTTCATT
CCCGAACCGGTGATCTCCGTGGCTGTGGAGCCCAAGACCAAGGGCGACATGGAGAAGCTCTCCAAAGCGCTGACGTCCCT
ATCCGAGGAAGACCCCACCTTCCGCGTCTCCACCGATGAGGAAACCGGCCAAACCGTAATCGCCGGCATGGGCGAGCTTC
ACCTTGAAATCCTGGTGGACCGCATGCTGCGGGAGTTCAAGGTGGAAGCCAACATCGGCGCCCCGCAGGTGTCGTATCGC
GAAACCATCCGCTCCTCCTCCAAAGGGGAAGGCAAGTTCGCTCGCCAAACCGGTGGTAAGGGTCAATACGGCCACGTGGT
GATCGAAATGGAGCCTGGTGAGCCCGGCACCGGCTTCGAATTCATCAACAAAATTGTTGGTGGCGCCGTTCCCAAGGAAT
TCATCAAGCCCGCTGAAATGGGCATGAAGGAAACCTGCGAATCTGGCGTGATTGCCGGTTTCCCGTTGATCGACGTGAAA
TGCACAATGGTCGACGGTTCTTATCACGACGTCGACTCTTCGGAGATGGCGTTCAAGATCGCCGGCTCCATGGCCTTCAA
AGACGGCGTCAAGAAGTGCAATCCCGTACTGCTTGAACCGATGATGAAGGTGGAAGTCGAGGTGCCCGAGGATTTCCTCG
GTTCCATCATCGGCGATCTCTCCTCCCGGAGAGGCCAAGTCGAGGGTCAGTCCATCGACGATGGCATCTCAAAGGTCTCT
GCAAAAGTGCCTCTGGCCGAGATGTTCGGCTACGCCACGCAGCTCCGCTCCATGACCCAGGGGAGGGGTATATTTTCAAT
GGAATTCAGCCGTTACGAGGAGGTTCCTCGCAACGTGGCCGAAGCCATTATTTCCAAGAATCAGGGAAATTCCTGA

Upstream 100 bases:

>100_bases
GCTACTAATCCAAACCTCCCTTTTGCGGGTCAACGGCTGCCTGAGGTCAGCCTGTAGAGTTGCGCCCGCTTTTTAGCAAC
ATTCCCCTTAGGAGCATCAC

Downstream 100 bases:

>100_bases
TCCTTCCCCCCTCTTCATTTACCCCCCGATTCTTCATTAACAATGGCCCGCGAGAAGTTTGAGAGGAACAAACCTCACGT
CAACATCGGCACCATCGGCC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MPRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTAWNDHRINII
DTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAA
PIQLPIGAEGDLSGIIDLVANKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAEL
KKGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRPSDDNAPFSALAFKVMADPYG
KLTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDREEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFI
PEPVISVAVEPKTKGDMEKLSKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYR
ETIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEMGMKETCESGVIAGFPLIDVK
CTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVS
AKVPLAEMFGYATQLRSMTQGRGIFSMEFSRYEEVPRNVAEAIISKNQGNS

Sequences:

>Translated_691_residues
MPRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTAWNDHRINII
DTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAA
PIQLPIGAEGDLSGIIDLVANKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAEL
KKGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRPSDDNAPFSALAFKVMADPYG
KLTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDREEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFI
PEPVISVAVEPKTKGDMEKLSKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYR
ETIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEMGMKETCESGVIAGFPLIDVK
CTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVS
AKVPLAEMFGYATQLRSMTQGRGIFSMEFSRYEEVPRNVAEAIISKNQGNS
>Mature_690_residues
PRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTAWNDHRINIID
TPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAAP
IQLPIGAEGDLSGIIDLVANKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAELK
KGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRPSDDNAPFSALAFKVMADPYGK
LTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDREEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFIP
EPVISVAVEPKTKGDMEKLSKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRE
TIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEMGMKETCESGVIAGFPLIDVKC
TMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVSA
KVPLAEMFGYATQLRSMTQGRGIFSMEFSRYEEVPRNVAEAIISKNQGNS

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=694, Percent_Identity=43.8040345821326, Blast_Score=578, Evalue=1e-165,
Organism=Homo sapiens, GI19923640, Length=728, Percent_Identity=39.6978021978022, Blast_Score=474, Evalue=1e-133,
Organism=Homo sapiens, GI25306287, Length=727, Percent_Identity=37.6891334250344, Blast_Score=435, Evalue=1e-122,
Organism=Homo sapiens, GI25306283, Length=443, Percent_Identity=43.3408577878104, Blast_Score=318, Evalue=1e-86,
Organism=Homo sapiens, GI157426893, Length=151, Percent_Identity=37.7483443708609, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI4503483, Length=496, Percent_Identity=26.008064516129, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI94966754, Length=134, Percent_Identity=38.8059701492537, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI310132016, Length=118, Percent_Identity=38.9830508474576, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI310110807, Length=118, Percent_Identity=38.9830508474576, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI310123363, Length=118, Percent_Identity=38.9830508474576, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI1789738, Length=699, Percent_Identity=60.9442060085837, Blast_Score=869, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=477, Percent_Identity=28.7211740041929, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI48994988, Length=175, Percent_Identity=41.1428571428571, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788922, Length=152, Percent_Identity=36.1842105263158, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17533571, Length=679, Percent_Identity=43.0044182621502, Blast_Score=537, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17556745, Length=699, Percent_Identity=28.6123032904149, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17506493, Length=492, Percent_Identity=26.8292682926829, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17557151, Length=148, Percent_Identity=38.5135135135135, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=30.5970149253731, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=30.5970149253731, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17552882, Length=135, Percent_Identity=34.0740740740741, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=691, Percent_Identity=42.1128798842258, Blast_Score=551, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322359, Length=798, Percent_Identity=32.7067669172932, Blast_Score=401, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6324707, Length=148, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320593, Length=148, Percent_Identity=40.5405405405405, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323320, Length=157, Percent_Identity=36.3057324840764, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324166, Length=144, Percent_Identity=32.6388888888889, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582462, Length=694, Percent_Identity=44.5244956772334, Blast_Score=599, Evalue=1e-171,
Organism=Drosophila melanogaster, GI221458488, Length=725, Percent_Identity=32.9655172413793, Blast_Score=360, Evalue=3e-99,
Organism=Drosophila melanogaster, GI24585711, Length=487, Percent_Identity=25.4620123203285, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585713, Length=487, Percent_Identity=25.4620123203285, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585709, Length=487, Percent_Identity=25.4620123203285, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI78706572, Length=149, Percent_Identity=38.255033557047, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574573, Length=140, Percent_Identity=36.4285714285714, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357743, Length=135, Percent_Identity=31.1111111111111, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 75273; Mature: 75142

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERG
CCCCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
ITITAAAISTAWNDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVW
EEEEEEHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAAPIQLPIGAEGDLSGIIDLVA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHH
NKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAEL
CCEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHH
KKGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRP
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCC
SDDNAPFSALAFKVMADPYGKLTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDR
CCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEECCHHHHHHHHHHEEEEECCCH
EEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFIPEPVISVAVEPKTKGDMEKL
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHEEEECCCCCCCHHHH
SKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYR
HHHHHHCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ETIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEM
HHHHCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHCCHHHC
GMKETCESGVIAGFPLIDVKCTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEP
CHHHHHCCCCEECCCEEEEEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHCCHHHHCC
MMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVSAKVPLAEMFGYATQLRSMTQ
HHEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GRGIFSMEFSRYEEVPRNVAEAIISKNQGNS
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PRDFPLDRVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERG
CCCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
ITITAAAISTAWNDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVW
EEEEEEHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RQADRYSVPRMVFVNKMDRTGADFLKVYGQIVDRLKAKAAPIQLPIGAEGDLSGIIDLVA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHH
NKAYIYKNDLGTDIEEAEIPADMADEAAEWRAKLMESVAENDEELIEKFLETGELTEAEL
CCEEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHH
KKGIRDGVLKHGLVPMLCGSAFKNKGVQLVLDAVVDYLPAPIDVPPIQGVLADGSEAVRP
HHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCC
SDDNAPFSALAFKVMADPYGKLTFVRMYSGVLSKGSYVMNSTKDVKERISRLVVLKADDR
CCCCCCHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEECCHHHHHHHHHHEEEEECCCH
EEVDQLRAGDLGAVLGLKNTTTGDTLCDPDNSIVLETLFIPEPVISVAVEPKTKGDMEKL
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEECCCCHHEEEECCCCCCCHHHH
SKALTSLSEEDPTFRVSTDEETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYR
HHHHHHCCCCCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ETIRSSSKGEGKFARQTGGKGQYGHVVIEMEPGEPGTGFEFINKIVGGAVPKEFIKPAEM
HHHHCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCHHHCCHHHC
GMKETCESGVIAGFPLIDVKCTMVDGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEP
CHHHHHCCCCEECCCEEEEEEEEECCCCCCCCCCHHEEEHHHHHHHHHHHHHCCHHHHCC
MMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIDDGISKVSAKVPLAEMFGYATQLRSMTQ
HHEEEEECCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
GRGIFSMEFSRYEEVPRNVAEAIISKNQGNS
CCCEEEEHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA