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The map label for this gene is bioA [H]

Identifier: 148243040

GI number: 148243040

Start: 1685826

End: 1687115

Strand: Direct

Name: bioA [H]

Synonym: SynRCC307_1941

Alternate gene names: 148243040

Gene position: 1685826-1687115 (Clockwise)

Preceding gene: 148243039

Following gene: 148243045

Centisome position: 75.77

GC content: 63.8

Gene sequence:

>1290_bases
ATGACTGAGATGGCAAGCAGCGGCTGGCATCCGCACCTCTGGCATCCCTTTACCCAGCCAGGGCGAGGCCCTGCTCCGAT
TCCGGTGCGCCGCGGCCAGGGGGTTTGGCTGGAACTCGACGACGGCCGCCGCTTGATCGATGGCATCAGCAGCTGGTGGG
TGACCCTGCATGGCCATGGGGAGCCCTGCATTGCTGAGGCCATTGGCCATCAAGCCAAAGAGCTCGAGCAGGTGATCTTT
GCCAACTTCCGCCATGGTCCGGCCAGCACCCTGTCAACGCGGTTGTGCGGCAAGTGGGATGGGCTGGATCGGATGTTTTT
CTCCGACAACGGCTCCACCGCCGTGGAGGTGGCCTTGAAGATGGCATGGCAGCACTGCCAACGGGAAGCACCGGAGCGGC
AGCAGGTGATCGCCTTTGACGGGGCGTATCACGGCGACACCTTTGGAGCCATGGCGCTCGGGGAGCGGGGCCTATTCAGC
GCCCCGTTTGAACCCTTGCTGTTTGCGGTGGCCCGAGCCCCTTGGCCCGCTACCTGGTGGGGAGATGGGGAGATTGAGCA
AAAGGAAGCCCAGGCCCTGCAACGGCTGGATGAGTTATTGCAAACCCCCACTGCTGCTGTGATCTTTGAGCCCCTGCTGC
AGGGAGCCGGTGGCATGGCGATGGTGCGTGAGACGTTCCTGCAAGCCGTCGAGCAACGGGCCCACGCGGCGGGTGCCCTG
GTGATTGCCGATGAGGTGCTCACGGGCTTTGGCCGCAGCGGCAGCCTGTTTGCCTGCCATCGCGCTGGCATTGCACCCGA
CATCGTCTCCCTCTCCAAAGGGCTCACGGCAGGATTTCTGCCGATGGGCGTGACCCTGGCCAGTGAGGCGCTTTATCAAA
GCTTTGTGGGCCCTGAGCCGGACCGCACGTTTTTCCATGGCCATAGCTTCACCGCCAACCCCTTGGGCTGTGCCGCGGCC
GTGGCCAGCCTCGAGCTGCTGGAGCGGGAACCCCAGCGCTACACAAGCATCGAAGCGCGGCATCGGCCGCACCTGGAACA
CTTGGCCGAGCACCGGCTGGTGACCAAACCACGGTTGCTCGGAGGAATTGCTGCCTTTGAGCTGCCAGGGGACAGCGGCT
ACCTCCAACCGATTGGTCTGGAGGTGCAGCGACTGGCCCTGGAACAAGGGCTGTTCATTCGCCCCCTGGGATCGGTCGTC
TACCTGATGCCACCGCTCGGCATCAACGACGGGGAATTGGCGCAGTGCTACGCCAGTTTGCAGGCGGTGCTGGATTCCCT
ACCGCTTTAA

Upstream 100 bases:

>100_bases
AGTGAAGGGCTGAGCCTGCGGGAAGCGGCACTGGTGCTGAATGCCATCGAAGCCGACGCCTTCGATGCAGCGGTGAACCC
TGGATGGATGGCCAAGCCCC

Downstream 100 bases:

>100_bases
GGCCCAGCCAGGATGGCGGCTTCCAGATCAGCGCGGCTCAAGCCATAGGAGAACGCCCGCTCGGTGCTGCTGCCCTGCTG
GCTCCAGCTGATGACCAGGC

Product: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTEMASSGWHPHLWHPFTQPGRGPAPIPVRRGQGVWLELDDGRRLIDGISSWWVTLHGHGEPCIAEAIGHQAKELEQVIF
ANFRHGPASTLSTRLCGKWDGLDRMFFSDNGSTAVEVALKMAWQHCQREAPERQQVIAFDGAYHGDTFGAMALGERGLFS
APFEPLLFAVARAPWPATWWGDGEIEQKEAQALQRLDELLQTPTAAVIFEPLLQGAGGMAMVRETFLQAVEQRAHAAGAL
VIADEVLTGFGRSGSLFACHRAGIAPDIVSLSKGLTAGFLPMGVTLASEALYQSFVGPEPDRTFFHGHSFTANPLGCAAA
VASLELLEREPQRYTSIEARHRPHLEHLAEHRLVTKPRLLGGIAAFELPGDSGYLQPIGLEVQRLALEQGLFIRPLGSVV
YLMPPLGINDGELAQCYASLQAVLDSLPL

Sequences:

>Translated_429_residues
MTEMASSGWHPHLWHPFTQPGRGPAPIPVRRGQGVWLELDDGRRLIDGISSWWVTLHGHGEPCIAEAIGHQAKELEQVIF
ANFRHGPASTLSTRLCGKWDGLDRMFFSDNGSTAVEVALKMAWQHCQREAPERQQVIAFDGAYHGDTFGAMALGERGLFS
APFEPLLFAVARAPWPATWWGDGEIEQKEAQALQRLDELLQTPTAAVIFEPLLQGAGGMAMVRETFLQAVEQRAHAAGAL
VIADEVLTGFGRSGSLFACHRAGIAPDIVSLSKGLTAGFLPMGVTLASEALYQSFVGPEPDRTFFHGHSFTANPLGCAAA
VASLELLEREPQRYTSIEARHRPHLEHLAEHRLVTKPRLLGGIAAFELPGDSGYLQPIGLEVQRLALEQGLFIRPLGSVV
YLMPPLGINDGELAQCYASLQAVLDSLPL
>Mature_428_residues
TEMASSGWHPHLWHPFTQPGRGPAPIPVRRGQGVWLELDDGRRLIDGISSWWVTLHGHGEPCIAEAIGHQAKELEQVIFA
NFRHGPASTLSTRLCGKWDGLDRMFFSDNGSTAVEVALKMAWQHCQREAPERQQVIAFDGAYHGDTFGAMALGERGLFSA
PFEPLLFAVARAPWPATWWGDGEIEQKEAQALQRLDELLQTPTAAVIFEPLLQGAGGMAMVRETFLQAVEQRAHAAGALV
IADEVLTGFGRSGSLFACHRAGIAPDIVSLSKGLTAGFLPMGVTLASEALYQSFVGPEPDRTFFHGHSFTANPLGCAAAV
ASLELLEREPQRYTSIEARHRPHLEHLAEHRLVTKPRLLGGIAAFELPGDSGYLQPIGLEVQRLALEQGLFIRPLGSVVY
LMPPLGINDGELAQCYASLQAVLDSLPL

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=413, Percent_Identity=25.90799031477, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI13994255, Length=338, Percent_Identity=27.2189349112426, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI37574042, Length=404, Percent_Identity=25.2475247524752, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI24119277, Length=427, Percent_Identity=25.5269320843091, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI226442705, Length=404, Percent_Identity=24.7524752475248, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI284507298, Length=328, Percent_Identity=25.609756097561, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=24.6819338422392, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=38.5882352941176, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI145693181, Length=292, Percent_Identity=34.9315068493151, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788044, Length=401, Percent_Identity=30.1745635910224, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789016, Length=405, Percent_Identity=30.3703703703704, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789759, Length=323, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787560, Length=412, Percent_Identity=28.3980582524272, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786349, Length=315, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144271, Length=412, Percent_Identity=24.2718446601942, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=24.5412844036697, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=337, Percent_Identity=26.7062314540059, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144274, Length=134, Percent_Identity=34.3283582089552, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324386, Length=456, Percent_Identity=29.6052631578947, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6323470, Length=446, Percent_Identity=24.8878923766816, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=27.2727272727273, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357415, Length=438, Percent_Identity=25.3424657534247, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI28574759, Length=441, Percent_Identity=24.2630385487528, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356575, Length=316, Percent_Identity=27.8481012658228, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI161085790, Length=417, Percent_Identity=24.220623501199, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 46707; Mature: 46576

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEMASSGWHPHLWHPFTQPGRGPAPIPVRRGQGVWLELDDGRRLIDGISSWWVTLHGHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCHHHHCCCEEEEEEECCC
EPCIAEAIGHQAKELEQVIFANFRHGPASTLSTRLCGKWDGLDRMFFSDNGSTAVEVALK
CHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHH
MAWQHCQREAPERQQVIAFDGAYHGDTFGAMALGERGLFSAPFEPLLFAVARAPWPATWW
HHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCC
GDGEIEQKEAQALQRLDELLQTPTAAVIFEPLLQGAGGMAMVRETFLQAVEQRAHAAGAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCE
VIADEVLTGFGRSGSLFACHRAGIAPDIVSLSKGLTAGFLPMGVTLASEALYQSFVGPEP
EEHHHHHHCCCCCCCEEEEHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
DRTFFHGHSFTANPLGCAAAVASLELLEREPQRYTSIEARHRPHLEHLAEHRLVTKPRLL
CCCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHCCCCCHHH
GGIAAFELPGDSGYLQPIGLEVQRLALEQGLFIRPLGSVVYLMPPLGINDGELAQCYASL
HCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCCHHHHHHHHHH
QAVLDSLPL
HHHHHHCCC
>Mature Secondary Structure 
TEMASSGWHPHLWHPFTQPGRGPAPIPVRRGQGVWLELDDGRRLIDGISSWWVTLHGHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCHHHHCCCEEEEEEECCC
EPCIAEAIGHQAKELEQVIFANFRHGPASTLSTRLCGKWDGLDRMFFSDNGSTAVEVALK
CHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHH
MAWQHCQREAPERQQVIAFDGAYHGDTFGAMALGERGLFSAPFEPLLFAVARAPWPATWW
HHHHHHHHCCCCHHEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCC
GDGEIEQKEAQALQRLDELLQTPTAAVIFEPLLQGAGGMAMVRETFLQAVEQRAHAAGAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCE
VIADEVLTGFGRSGSLFACHRAGIAPDIVSLSKGLTAGFLPMGVTLASEALYQSFVGPEP
EEHHHHHHCCCCCCCEEEEHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCC
DRTFFHGHSFTANPLGCAAAVASLELLEREPQRYTSIEARHRPHLEHLAEHRLVTKPRLL
CCCEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHCCCHHHHHHHHHCCCCCHHH
GGIAAFELPGDSGYLQPIGLEVQRLALEQGLFIRPLGSVVYLMPPLGINDGELAQCYASL
HCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEECCCEEEEECCCCCCCHHHHHHHHHH
QAVLDSLPL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2110099 [H]