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The map label for this gene is ribD [H]

Identifier: 148242850

GI number: 148242850

Start: 1532068

End: 1533168

Strand: Direct

Name: ribD [H]

Synonym: SynRCC307_1751

Alternate gene names: 148242850

Gene position: 1532068-1533168 (Clockwise)

Preceding gene: 148242849

Following gene: 148242853

Centisome position: 68.86

GC content: 68.66

Gene sequence:

>1101_bases
GTGAGCTGCCCACCTATCCCCTCTGATCGCCATTGGATGGCCAGGGCCTTGGCCCTCGCTGCCCTCGCTGATGGCCGCAC
CAGCCCCAACCCGCTGGTGGGCTGCGTGGTGCTTGATGCCAACGGCGAGCTTGTGGGTGAGGGCTACCACCGCCAAGCCG
GTGAACCCCACGCTGAAGTGATGGCGTTGCGCCGAGCTGGGGATCGCGCCAAAGGCGGCACGCTCTACGTGACGCTGGAG
CCCTGCTGCCACCACGGCCGCACGCCCCCCTGCTCAGAGGCGGTGATAGCCGCTGGCCTGCGCCGGGTGGTGATTGCCCT
GGCTGATCCCGATCCCCGTGTGGCCGGCGGCGGCATCGCCCAGCTCAAGGCAGCTGGCATGGAGGTGATCAGCGGCGTGC
GCCAAGCCGAAGCCGCCCAGCAAAATCGCGCCTTCCTGCACCGCATTCGCACAGGCCGCCCCTGGGGCCTGTTGAAGTGG
GCCATGAGCCTCGATGGCCGAACGGCTCTGCCCAATGGCGCCAGCCAATGGATCAGCAGCCCGCCAGCCCGCAGCTGGGT
GCATCACCTGCGCGCTGCCGTTGATGCGGTGATCGTTGGCGGCGGCACCGTTCGCGCCGACAACCCCCTGCTCACCAGCC
GCGGGCAGCGCAGCCCCGAGCCGCTGCGAGTGGTGCTCAGCCGCACTCTTGATTTGCCAAGCGATGCCCAGCTTTGGGAT
CAAACCAGCGCCACCACCCTGGTGGCCCATGGCCCCGAGGCCCCAGCGCAAGCCAGGCAGCAACTCGATCAGCTCGGGGT
GGAGCGCATCGAGCTCGTGGCCTGCGAACCAGCAGCCTTGCTCGAGGCCTTGGCGCAGCGCGGCTGCAACCGGGTGCTGT
GGGAATGCGGCCCCCAATTAGCGGCGGCCGCCATCGCTTCCGGCTGCGTGCAAGAAACAGCAGCCGTGGTGGCGCCAGCG
CTGTTGGGCGGCGCAGCGGCCCGCACGCCCCTGGGCGATCTGGGCTTCACCGCCATGGATCAGGTGATTCGCCTTGCGCC
CAATATCCCGCAGGCACTGGGCAGCGATTGGCTGTTTCAGTCGCTGCTGCCAGAAGACTGA

Upstream 100 bases:

>100_bases
CCGCTACTGGCTGAACTAAACAAGAACCGGCCACTGCGGCTGCAACTGCCTGGTGTGTTCAACGAACTGCCGGTGCCCCC
CTTTGTGGTGAAGGAATGGC

Downstream 100 bases:

>100_bases
GCTGAGCCAGCAAAGCGGCCAATCAGCACCCCCATCACCACCGCTAGATAGAGCGGGCCGGCAATGCTGGTCACCACGCT
GAGCATGCGAGCCAACGGCA

Product: riboflavin biosynthesis protein ribD (diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase)

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSCPPIPSDRHWMARALALAALADGRTSPNPLVGCVVLDANGELVGEGYHRQAGEPHAEVMALRRAGDRAKGGTLYVTLE
PCCHHGRTPPCSEAVIAAGLRRVVIALADPDPRVAGGGIAQLKAAGMEVISGVRQAEAAQQNRAFLHRIRTGRPWGLLKW
AMSLDGRTALPNGASQWISSPPARSWVHHLRAAVDAVIVGGGTVRADNPLLTSRGQRSPEPLRVVLSRTLDLPSDAQLWD
QTSATTLVAHGPEAPAQARQQLDQLGVERIELVACEPAALLEALAQRGCNRVLWECGPQLAAAAIASGCVQETAAVVAPA
LLGGAAARTPLGDLGFTAMDQVIRLAPNIPQALGSDWLFQSLLPED

Sequences:

>Translated_366_residues
MSCPPIPSDRHWMARALALAALADGRTSPNPLVGCVVLDANGELVGEGYHRQAGEPHAEVMALRRAGDRAKGGTLYVTLE
PCCHHGRTPPCSEAVIAAGLRRVVIALADPDPRVAGGGIAQLKAAGMEVISGVRQAEAAQQNRAFLHRIRTGRPWGLLKW
AMSLDGRTALPNGASQWISSPPARSWVHHLRAAVDAVIVGGGTVRADNPLLTSRGQRSPEPLRVVLSRTLDLPSDAQLWD
QTSATTLVAHGPEAPAQARQQLDQLGVERIELVACEPAALLEALAQRGCNRVLWECGPQLAAAAIASGCVQETAAVVAPA
LLGGAAARTPLGDLGFTAMDQVIRLAPNIPQALGSDWLFQSLLPED
>Mature_365_residues
SCPPIPSDRHWMARALALAALADGRTSPNPLVGCVVLDANGELVGEGYHRQAGEPHAEVMALRRAGDRAKGGTLYVTLEP
CCHHGRTPPCSEAVIAAGLRRVVIALADPDPRVAGGGIAQLKAAGMEVISGVRQAEAAQQNRAFLHRIRTGRPWGLLKWA
MSLDGRTALPNGASQWISSPPARSWVHHLRAAVDAVIVGGGTVRADNPLLTSRGQRSPEPLRVVLSRTLDLPSDAQLWDQ
TSATTLVAHGPEAPAQARQQLDQLGVERIELVACEPAALLEALAQRGCNRVLWECGPQLAAAAIASGCVQETAAVVAPAL
LGGAAARTPLGDLGFTAMDQVIRLAPNIPQALGSDWLFQSLLPED

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=349, Percent_Identity=43.2664756446991, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38518; Mature: 38386

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCPPIPSDRHWMARALALAALADGRTSPNPLVGCVVLDANGELVGEGYHRQAGEPHAEV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCHHCCCCCCHHHH
MALRRAGDRAKGGTLYVTLEPCCHHGRTPPCSEAVIAAGLRRVVIALADPDPRVAGGGIA
HHHHHCCCCCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCHH
QLKAAGMEVISGVRQAEAAQQNRAFLHRIRTGRPWGLLKWAMSLDGRTALPNGASQWISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHCC
PPARSWVHHLRAAVDAVIVGGGTVRADNPLLTSRGQRSPEPLRVVLSRTLDLPSDAQLWD
CCHHHHHHHHHHHHHEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHC
QTSATTLVAHGPEAPAQARQQLDQLGVERIELVACEPAALLEALAQRGCNRVLWECGPQL
CCCCEEEEECCCCCHHHHHHHHHHHCHHHEEEEECCHHHHHHHHHHHCCHHHHHHCCHHH
AAAAIASGCVQETAAVVAPALLGGAAARTPLGDLGFTAMDQVIRLAPNIPQALGSDWLFQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCHHHHCHHHHHH
SLLPED
HHCCCC
>Mature Secondary Structure 
SCPPIPSDRHWMARALALAALADGRTSPNPLVGCVVLDANGELVGEGYHRQAGEPHAEV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCHHCCCCCCHHHH
MALRRAGDRAKGGTLYVTLEPCCHHGRTPPCSEAVIAAGLRRVVIALADPDPRVAGGGIA
HHHHHCCCCCCCCEEEEEECHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCHH
QLKAAGMEVISGVRQAEAAQQNRAFLHRIRTGRPWGLLKWAMSLDGRTALPNGASQWISS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHCC
PPARSWVHHLRAAVDAVIVGGGTVRADNPLLTSRGQRSPEPLRVVLSRTLDLPSDAQLWD
CCHHHHHHHHHHHHHEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHC
QTSATTLVAHGPEAPAQARQQLDQLGVERIELVACEPAALLEALAQRGCNRVLWECGPQL
CCCCEEEEECCCCCHHHHHHHHHHHCHHHEEEEECCHHHHHHHHHHHCCHHHHHHCCHHH
AAAAIASGCVQETAAVVAPALLGGAAARTPLGDLGFTAMDQVIRLAPNIPQALGSDWLFQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCHHHHCHHHHHH
SLLPED
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]