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The map label for this gene is ubiB [C]

Identifier: 148242841

GI number: 148242841

Start: 1523831

End: 1525486

Strand: Direct

Name: ubiB [C]

Synonym: SynRCC307_1742

Alternate gene names: 148242841

Gene position: 1523831-1525486 (Clockwise)

Preceding gene: 148242840

Following gene: 148242842

Centisome position: 68.49

GC content: 63.41

Gene sequence:

>1656_bases
ATGTCCGTGCTCTCGGTGTTCGATGGCTCCGCGCGCGCGCTGGAGATCGCGCGGGTTGTCACCCGTTATGAGTGGTCCTT
CCTTTCACAGCTCCTCAACCGCGGCGATGCCGCTGAAACGCGCCTGCCCCAACCGCAGGTGCTCTGCCAAATCCTGATCG
AGCTGGGCCCGGTCTACGTGAAGCTTGGCCAGCTGCTGAGCACCCGCCCGGATCTGCTGGCCAAGGACTACATCGATGCC
CTCAGCAGCCTGCAGGCCGATGTGCCGGTGGAACCCTGGGAGCAAATCGAGCCGTTGATGCGCGAAGCGCTGGGCCAAGA
GGTTGATCAAGCCTTTGGCCAGTTCGAGCGCGAGCCGATCGCCGCCGGCAGCATCGGCCAGGTGTATCGGGCCAGCCTTC
ACGACAACACTCCGGTGGCGGTGAAGGTGCTGCGGCCCGGCATCGAGCAACTGGTCCAAGAAGACGGCCGCTTGCTGCGC
AAGATCGCCAGCTTGGCCTCAGCAACTGCTCTTGGTGCCAGCTACGACCTCGAAGGCCTGGCGGAGCAGGTGCTGCAAGC
GATTGGCCGCGAGCTGGATTTCCGCGTCGAAGCCGGCAACACCTTGAAGTTGCAGGGCATCTTGGGGCGCTCGAAGTTTG
TGCCCAACGGCAGCCTCAAGGTGCCCAATGTGGTGCCGGCCCTCTCCAGCCAGCGGGTGCTGGTGCTCGAGTGGATTGAT
GGGCACAACATCCTTGGCGAGGAGGCCAAAGCAGCCCTCACCCAGCACGGCTCCAGCGTTGATGCCGCCACCAAGGCATT
GCTGGGGGCGTTTGTGGAGCAGTACTTCGTGGAAGGCTTCTTCCACGCCGATCCCCATCCCGGCAACCTCAAGGTGGATG
GCGATGGCGTCATCACCCTGCTCGATGAGGGGATGGTGGGGATGTTTGATCCCCGCAGCCGCACCACGCTGTTGGATCTG
GTGCTGGCGCTGATCAACCAAGACGGAGCCCGCGCCACCGACCTATTAGTGCAATTGGCCCCGCCGCCAGCAGGGGTGAA
GGTGGACCGGCGGCAGCTGCAAAGTCAGCTGCAACAACTGATCGCCAGCAGCTTTTCCAAACCGCTGCAGGAGCTCAATT
TCGCCATCTTTCTGGCCGAGCTGCTGCGACTGGCCAACAAGGTGGGGCTCAGGGTGCCGGGCACCATCGGCCTGTTTGTG
AAGTCGGTCACCAACCTTGAAGGCGTGGGCGGATCGCTCAACCCCAACTTCAGCTTCACCGCCGAAATGCAGCCGTTGGT
GGGGCAGCTGCTCAGCGATTCGATGCTGCTGCCCAAAGAGCGGATGATGCAGTTCGGGCTGGATCTGCGCAGCTTCAGCA
TCGATGCGCCGCGCCAACTCAGCCAGCTGCTGCGGCGCTTCAGCAGCGATGAGCTGGTGTTCTCGCTGCAACTCGAAGGA
CTGGAAGCCCTGCGCACCAGCCTTGAGCGGCTCTCGCAACGGGTGTCGCTGGCCATCCTGGTGGCCTCACTGCTGCTCAG
CGCCACCTTGATGGCTTCCTTGGCCCAGCAGGAGCTGCTGCGCACCGTCAGTGAAGGCCTCTTCATCAGCGCCACCCTGT
TTGGCCTCTGGCTGATCGTTTCGCTGCTGCGCTCCGGCCGCAGCGGACGCACTTAA

Upstream 100 bases:

>100_bases
CCGCCGCCTGTTCACCAGCGATCTGCGTTTTCTCGAACAGTTCTGAGTCAAGCGAGCTGAGGCTGCTTAATTTCCGGCTA
GAGGCCTTTGGCAGCCGGCC

Downstream 100 bases:

>100_bases
CGAAGTCCTAGTAACAGGGAAAGCCCGCCTAAACTCAGGCACCCACTTGCTCGTGACCGGTGCCCTGTGCCGGACTGATC
GTTAACGACGGCAAGGATCT

Product: protein kinase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSVLSVFDGSARALEIARVVTRYEWSFLSQLLNRGDAAETRLPQPQVLCQILIELGPVYVKLGQLLSTRPDLLAKDYIDA
LSSLQADVPVEPWEQIEPLMREALGQEVDQAFGQFEREPIAAGSIGQVYRASLHDNTPVAVKVLRPGIEQLVQEDGRLLR
KIASLASATALGASYDLEGLAEQVLQAIGRELDFRVEAGNTLKLQGILGRSKFVPNGSLKVPNVVPALSSQRVLVLEWID
GHNILGEEAKAALTQHGSSVDAATKALLGAFVEQYFVEGFFHADPHPGNLKVDGDGVITLLDEGMVGMFDPRSRTTLLDL
VLALINQDGARATDLLVQLAPPPAGVKVDRRQLQSQLQQLIASSFSKPLQELNFAIFLAELLRLANKVGLRVPGTIGLFV
KSVTNLEGVGGSLNPNFSFTAEMQPLVGQLLSDSMLLPKERMMQFGLDLRSFSIDAPRQLSQLLRRFSSDELVFSLQLEG
LEALRTSLERLSQRVSLAILVASLLLSATLMASLAQQELLRTVSEGLFISATLFGLWLIVSLLRSGRSGRT

Sequences:

>Translated_551_residues
MSVLSVFDGSARALEIARVVTRYEWSFLSQLLNRGDAAETRLPQPQVLCQILIELGPVYVKLGQLLSTRPDLLAKDYIDA
LSSLQADVPVEPWEQIEPLMREALGQEVDQAFGQFEREPIAAGSIGQVYRASLHDNTPVAVKVLRPGIEQLVQEDGRLLR
KIASLASATALGASYDLEGLAEQVLQAIGRELDFRVEAGNTLKLQGILGRSKFVPNGSLKVPNVVPALSSQRVLVLEWID
GHNILGEEAKAALTQHGSSVDAATKALLGAFVEQYFVEGFFHADPHPGNLKVDGDGVITLLDEGMVGMFDPRSRTTLLDL
VLALINQDGARATDLLVQLAPPPAGVKVDRRQLQSQLQQLIASSFSKPLQELNFAIFLAELLRLANKVGLRVPGTIGLFV
KSVTNLEGVGGSLNPNFSFTAEMQPLVGQLLSDSMLLPKERMMQFGLDLRSFSIDAPRQLSQLLRRFSSDELVFSLQLEG
LEALRTSLERLSQRVSLAILVASLLLSATLMASLAQQELLRTVSEGLFISATLFGLWLIVSLLRSGRSGRT
>Mature_550_residues
SVLSVFDGSARALEIARVVTRYEWSFLSQLLNRGDAAETRLPQPQVLCQILIELGPVYVKLGQLLSTRPDLLAKDYIDAL
SSLQADVPVEPWEQIEPLMREALGQEVDQAFGQFEREPIAAGSIGQVYRASLHDNTPVAVKVLRPGIEQLVQEDGRLLRK
IASLASATALGASYDLEGLAEQVLQAIGRELDFRVEAGNTLKLQGILGRSKFVPNGSLKVPNVVPALSSQRVLVLEWIDG
HNILGEEAKAALTQHGSSVDAATKALLGAFVEQYFVEGFFHADPHPGNLKVDGDGVITLLDEGMVGMFDPRSRTTLLDLV
LALINQDGARATDLLVQLAPPPAGVKVDRRQLQSQLQQLIASSFSKPLQELNFAIFLAELLRLANKVGLRVPGTIGLFVK
SVTNLEGVGGSLNPNFSFTAEMQPLVGQLLSDSMLLPKERMMQFGLDLRSFSIDAPRQLSQLLRRFSSDELVFSLQLEGL
EALRTSLERLSQRVSLAILVASLLLSATLMASLAQQELLRTVSEGLFISATLFGLWLIVSLLRSGRSGRT

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=302, Percent_Identity=30.1324503311258, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI41393593, Length=280, Percent_Identity=32.1428571428571, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI217035081, Length=280, Percent_Identity=29.6428571428571, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI27363457, Length=289, Percent_Identity=28.719723183391, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI217416386, Length=245, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI2367309, Length=399, Percent_Identity=29.0726817042606, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17559152, Length=281, Percent_Identity=28.4697508896797, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32565180, Length=290, Percent_Identity=24.4827586206897, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323282, Length=285, Percent_Identity=29.1228070175439, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325148, Length=481, Percent_Identity=22.4532224532225, Blast_Score=100, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6321319, Length=249, Percent_Identity=25.7028112449799, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI22024280, Length=322, Percent_Identity=27.639751552795, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24662575, Length=262, Percent_Identity=30.1526717557252, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI18859849, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60014; Mature: 59883

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLSVFDGSARALEIARVVTRYEWSFLSQLLNRGDAAETRLPQPQVLCQILIELGPVYV
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KLGQLLSTRPDLLAKDYIDALSSLQADVPVEPWEQIEPLMREALGQEVDQAFGQFEREPI
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAGSIGQVYRASLHDNTPVAVKVLRPGIEQLVQEDGRLLRKIASLASATALGASYDLEGL
CCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AEQVLQAIGRELDFRVEAGNTLKLQGILGRSKFVPNGSLKVPNVVPALSSQRVLVLEWID
HHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GHNILGEEAKAALTQHGSSVDAATKALLGAFVEQYFVEGFFHADPHPGNLKVDGDGVITL
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
LDEGMVGMFDPRSRTTLLDLVLALINQDGARATDLLVQLAPPPAGVKVDRRQLQSQLQQL
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
IASSFSKPLQELNFAIFLAELLRLANKVGLRVPGTIGLFVKSVTNLEGVGGSLNPNFSFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
AEMQPLVGQLLSDSMLLPKERMMQFGLDLRSFSIDAPRQLSQLLRRFSSDELVFSLQLEG
CCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCEEEEEEHHH
LEALRTSLERLSQRVSLAILVASLLLSATLMASLAQQELLRTVSEGLFISATLFGLWLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SLLRSGRSGRT
HHHHCCCCCCC
>Mature Secondary Structure 
SVLSVFDGSARALEIARVVTRYEWSFLSQLLNRGDAAETRLPQPQVLCQILIELGPVYV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KLGQLLSTRPDLLAKDYIDALSSLQADVPVEPWEQIEPLMREALGQEVDQAFGQFEREPI
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AAGSIGQVYRASLHDNTPVAVKVLRPGIEQLVQEDGRLLRKIASLASATALGASYDLEGL
CCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
AEQVLQAIGRELDFRVEAGNTLKLQGILGRSKFVPNGSLKVPNVVPALSSQRVLVLEWID
HHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GHNILGEEAKAALTQHGSSVDAATKALLGAFVEQYFVEGFFHADPHPGNLKVDGDGVITL
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
LDEGMVGMFDPRSRTTLLDLVLALINQDGARATDLLVQLAPPPAGVKVDRRQLQSQLQQL
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
IASSFSKPLQELNFAIFLAELLRLANKVGLRVPGTIGLFVKSVTNLEGVGGSLNPNFSFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEE
AEMQPLVGQLLSDSMLLPKERMMQFGLDLRSFSIDAPRQLSQLLRRFSSDELVFSLQLEG
CCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCCCEEEEEEHHH
LEALRTSLERLSQRVSLAILVASLLLSATLMASLAQQELLRTVSEGLFISATLFGLWLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SLLRSGRSGRT
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]