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The map label for this gene is pheS [H]

Identifier: 148242840

GI number: 148242840

Start: 1522769

End: 1523776

Strand: Direct

Name: pheS [H]

Synonym: SynRCC307_1741

Alternate gene names: 148242840

Gene position: 1522769-1523776 (Clockwise)

Preceding gene: 148242838

Following gene: 148242841

Centisome position: 68.44

GC content: 65.48

Gene sequence:

>1008_bases
TTGAGCAGCGCTCCCACCCTGGAGGAGATCACCAGCGCGTTGGAGGCCTTGGAGGCGGAGGCCGCTGCCGCGATCGCTGA
AGCCCCCGATGCCGCAGCCCTCGAGCAGCTGCGAATCGATCTTTTAGGCAAAAAAGGCAAGCTATCTGGCGTGCTGGGCG
CCATGGGCAAGCTGCCCGGCGATCAGCGCCCAGTGGTGGGCCAGCGGGCCAATGTGCTGAAAACGCAGGTGCAATCGCTG
CTGCAGGAGCGCCAAAGCGCCCTCAAAGAAGCGGCACTGGAAGCCCGCATCGCCAGCGAAACGATCGATGTCACCCTGCC
GCCGGTGTACACACCCGCCGGCCATCGCCATCCGCTGCTGAGCACCACCGACGCGATCGTCGACATCTTCTGCGGCCTCG
GCTACCGGGTGGTGGAAGGCCCCGACATCGAGAGCGACTACTACAACTTCTCGGCCCTCAACATCCCCGAGGAGCATCCC
GCCCGGGACATGCAGGACACCTTCTACTTGCCGGGTGATCGCCTGCTGCGCACCCACACCTCACCGGTGCAGATTCGCCA
TCTCGAATCCAACCCCCCGCCGGTGCGCGTGATCGCCCCGGGCCGCGTCTACCGCCGTGATGCCGTTGATGCCACCCACT
CGCCGGTGTTCCACCAGGTGGAGGTGTTGGCCATTGATGAAGGGCTCGACTTCAGCCACCTCCGCGGCACGGTGAGCCAC
TTCCTCAAGGCCTTTTTTGGTGATCTGCCGGTGCGCTTCCGCGCCAGCTACTTCCCCTTCACCGAACCCAGCGCCGAGGT
GGATGTGCAATGGCGCGGCCGCTGGCTGGAGGTGATGGGCTGCGGCATGGTCGACCCCGCCGTGCTGGAGGGCATGGGGC
TCGACCCCGAGCGCTGGAGCGGCTTTGCAGCGGGCCTTGGCGTTGAGCGCTTCTGCATGGTGCGCCACGGCATCGACGAC
ATCCGCCGCCTGTTCACCAGCGATCTGCGTTTTCTCGAACAGTTCTGA

Upstream 100 bases:

>100_bases
GATGCCTTCGGCGAAGACCCCGTCGTCATTGCTGATCAGGATCTTGAGGGGGGAAGCCATCGAAAGGCGATACTGCCCCA
CGCACGTTAGGCCGACTCCC

Downstream 100 bases:

>100_bases
GTCAAGCGAGCTGAGGCTGCTTAATTTCCGGCTAGAGGCCTTTGGCAGCCGGCCATGTCCGTGCTCTCGGTGTTCGATGG
CTCCGCGCGCGCGCTGGAGA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSSAPTLEEITSALEALEAEAAAAIAEAPDAAALEQLRIDLLGKKGKLSGVLGAMGKLPGDQRPVVGQRANVLKTQVQSL
LQERQSALKEAALEARIASETIDVTLPPVYTPAGHRHPLLSTTDAIVDIFCGLGYRVVEGPDIESDYYNFSALNIPEEHP
ARDMQDTFYLPGDRLLRTHTSPVQIRHLESNPPPVRVIAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVSH
FLKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGMGLDPERWSGFAAGLGVERFCMVRHGIDD
IRRLFTSDLRFLEQF

Sequences:

>Translated_335_residues
MSSAPTLEEITSALEALEAEAAAAIAEAPDAAALEQLRIDLLGKKGKLSGVLGAMGKLPGDQRPVVGQRANVLKTQVQSL
LQERQSALKEAALEARIASETIDVTLPPVYTPAGHRHPLLSTTDAIVDIFCGLGYRVVEGPDIESDYYNFSALNIPEEHP
ARDMQDTFYLPGDRLLRTHTSPVQIRHLESNPPPVRVIAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVSH
FLKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGMGLDPERWSGFAAGLGVERFCMVRHGIDD
IRRLFTSDLRFLEQF
>Mature_334_residues
SSAPTLEEITSALEALEAEAAAAIAEAPDAAALEQLRIDLLGKKGKLSGVLGAMGKLPGDQRPVVGQRANVLKTQVQSLL
QERQSALKEAALEARIASETIDVTLPPVYTPAGHRHPLLSTTDAIVDIFCGLGYRVVEGPDIESDYYNFSALNIPEEHPA
RDMQDTFYLPGDRLLRTHTSPVQIRHLESNPPPVRVIAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVSHF
LKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGMGLDPERWSGFAAGLGVERFCMVRHGIDDI
RRLFTSDLRFLEQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=259, Percent_Identity=35.5212355212355, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI5729820, Length=230, Percent_Identity=33.4782608695652, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1788007, Length=326, Percent_Identity=53.3742331288344, Blast_Score=347, Evalue=5e-97,
Organism=Caenorhabditis elegans, GI17508957, Length=263, Percent_Identity=32.6996197718631, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32563657, Length=263, Percent_Identity=32.6996197718631, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32566635, Length=301, Percent_Identity=32.2259136212625, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321087, Length=270, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6325304, Length=88, Percent_Identity=45.4545454545455, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18858079, Length=271, Percent_Identity=32.8413284132841, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI17137424, Length=278, Percent_Identity=30.9352517985612, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 36967; Mature: 36836

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAPTLEEITSALEALEAEAAAAIAEAPDAAALEQLRIDLLGKKGKLSGVLGAMGKLPG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
DQRPVVGQRANVLKTQVQSLLQERQSALKEAALEARIASETIDVTLPPVYTPAGHRHPLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCC
STTDAIVDIFCGLGYRVVEGPDIESDYYNFSALNIPEEHPARDMQDTFYLPGDRLLRTHT
HHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCCHHHHCCC
SPVQIRHLESNPPPVRVIAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVSH
CCEEEEEECCCCCCEEEECCCCHHHHHCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHH
FLKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGMGLDPERWS
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHCCCCCHHHHC
GFAAGLGVERFCMVRHGIDDIRRLFTSDLRFLEQF
CHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSAPTLEEITSALEALEAEAAAAIAEAPDAAALEQLRIDLLGKKGKLSGVLGAMGKLPG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
DQRPVVGQRANVLKTQVQSLLQERQSALKEAALEARIASETIDVTLPPVYTPAGHRHPLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCC
STTDAIVDIFCGLGYRVVEGPDIESDYYNFSALNIPEEHPARDMQDTFYLPGDRLLRTHT
HHHHHHHHHHHCCCEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCCCHHHHCCC
SPVQIRHLESNPPPVRVIAPGRVYRRDAVDATHSPVFHQVEVLAIDEGLDFSHLRGTVSH
CCEEEEEECCCCCCEEEECCCCHHHHHCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHH
FLKAFFGDLPVRFRASYFPFTEPSAEVDVQWRGRWLEVMGCGMVDPAVLEGMGLDPERWS
HHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHCCCCCHHHHC
GFAAGLGVERFCMVRHGIDDIRRLFTSDLRFLEQF
CHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917641 [H]