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The map label for this gene is pdxJ

Identifier: 148242652

GI number: 148242652

Start: 1367013

End: 1367771

Strand: Direct

Name: pdxJ

Synonym: SynRCC307_1553

Alternate gene names: 148242652

Gene position: 1367013-1367771 (Clockwise)

Preceding gene: 148242646

Following gene: 148242653

Centisome position: 61.44

GC content: 63.11

Gene sequence:

>759_bases
ATGGCCAGTCTCGGCATCAACCTGGATCACATCGCCACGGTTCGGCAGGCCCGCCGAACCGTGGAGCCAGACCCTGTGCA
TTTGGCTTTGCTGGCCGAATTGGGCGGCGCCGATGGCATCACGGTGCATCTGCGTGAAGACCGGCGCCACATCCAAGACC
GCGATGTGGAACTGCTGCGTCAAACCGTGCGGACACGGCTGAATTTGGAGATGGCCGCCACCGCTGAAATGGTGGCCATC
GCCTTAACGATCAAGCCCGACATGGTGACCCTGGTGCCGGAAAAACGGCAGGAGGTCACCACCGAAGGCGGCCTTGATGT
GGTGAGCCAAGCAGCCGCGCTTCAGGGACAAATCAGCCAGCTCCAAGGGGCCGGGATCCCGGTCAGCCTGTTTGTGGATC
CCGAGCGTGCGCAACTCCAAGCCAGCCAGCGCAGTGGAGCGCGCTGGGTTGAACTGCACACTGGCAGCTATGCGGAGGCG
AGCTGGAGCCAGCAGCCCCTTGAGCTCGCACGGCTCATCGAGGGCACCACCGAGGCCCGGCAACTGGGTTTGCGCGTCAA
CGCAGGACACGGCCTCACCTACCAAAACGTGGAGCCGATCGCAGCGATCTCCGGCATGGAGGAGCTCAACATTGGCCACA
CCGTGATGGCCCGTGCCATGGCCGTTGGTTTGCAAGAGGCGGTCAAGCAAATGAAGGAGTTGGTGAGCGCACCGCGCCAA
GAGCCCCTCTTTGGCGCAGGGCTTGCTGCAGAATCCTGA

Upstream 100 bases:

>100_bases
CGCCAGGCGACTCGCTGCCATGGGATCGCTGGAGCTGGCCATAGCTCCGACCTTATCGAGCGAAGGCCTTCCTTAAATTG
AATGCTGGACAGCAGTTGCG

Downstream 100 bases:

>100_bases
GCTGCTCGAGAAGCCGATGTCCACCTATTACTTCGTGGCCGCTAGCGCAGCGTTCCTGACTGAAGAGGAACCCTTGGAAG
AAGTGCTGCGTGAGCGCGTG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLRQTVRTRLNLEMAATAEMVAI
ALTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQLQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEA
SWSQQPLELARLIEGTTEARQLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQ
EPLFGAGLAAES

Sequences:

>Translated_252_residues
MASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLRQTVRTRLNLEMAATAEMVAI
ALTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQLQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEA
SWSQQPLELARLIEGTTEARQLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQ
EPLFGAGLAAES
>Mature_251_residues
ASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLRQTVRTRLNLEMAATAEMVAIA
LTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQLQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEAS
WSQQPLELARLIEGTTEARQLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQE
PLFGAGLAAES

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=237, Percent_Identity=58.2278481012658, Blast_Score=277, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_SYNR3 (A5GU97)

Other databases:

- EMBL:   CT978603
- RefSeq:   YP_001227809.1
- ProteinModelPortal:   A5GU97
- SMR:   A5GU97
- STRING:   A5GU97
- GeneID:   5157793
- GenomeReviews:   CT978603_GR
- KEGG:   syr:SynRCC307_1553
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 27237; Mature: 27105

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 190-190 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLR
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEECHHHHHHHHHHHHHH
QTVRTRLNLEMAATAEMVAIALTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQ
HHHHHHHCHHHHHHHEEEEEEEEECCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHH
LQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEASWSQQPLELARLIEGTTEAR
HCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHH
QLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQ
HHCCEEECCCCCEECCCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EPLFGAGLAAES
CCCCCCCCCCCC
>Mature Secondary Structure 
ASLGINLDHIATVRQARRTVEPDPVHLALLAELGGADGITVHLREDRRHIQDRDVELLR
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCEEEEEECHHHHHHHHHHHHHH
QTVRTRLNLEMAATAEMVAIALTIKPDMVTLVPEKRQEVTTEGGLDVVSQAAALQGQISQ
HHHHHHHCHHHHHHHEEEEEEEEECCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHH
LQGAGIPVSLFVDPERAQLQASQRSGARWVELHTGSYAEASWSQQPLELARLIEGTTEAR
HCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHH
QLGLRVNAGHGLTYQNVEPIAAISGMEELNIGHTVMARAMAVGLQEAVKQMKELVSAPRQ
HHCCEEECCCCCEECCCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EPLFGAGLAAES
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA