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The map label for this gene is gpt [C]

Identifier: 148242560

GI number: 148242560

Start: 1298162

End: 1298710

Strand: Direct

Name: gpt [C]

Synonym: SynRCC307_1461

Alternate gene names: 148242560

Gene position: 1298162-1298710 (Clockwise)

Preceding gene: 148242559

Following gene: 148242561

Centisome position: 58.35

GC content: 62.66

Gene sequence:

>549_bases
ATGACAGCACTGCCCCAGCTCAAGCCCCCGGCCATCAGCGACAACACCGCTGGTGAGCTGGTGGTGAGCTGGGAGCAATA
CCACCGGCTGATCGAGCACCTGGCGCTGCAACTGCATCAAGCCGCAGCGGATTTTGATCAGATCGTGGCCCTCTCCCGCG
GCGGTTTGCGGGTGGGTGATCTGCTCTCCCGTCTGTTCGATCGGCCCTTGGTGGTGATGGCGGCCAGCAGCTACAGCGGC
GATGGCGATCGCATTCAGGGCCAACTGAAGCTCGGCCATCAACTGGCCCACACCTGCGACCAGCTAGGGCCTCGGCTGCT
GCTGGTGGACGACTTGGTGGATAGCGGCACCACCTTGGTGGAGGCCAGCGCCTGGCTCAACACAGAAGTGAGGCCATCCC
AACTGCTCACGGGGGTGCTGTGGCTCAAAGGCGGCAGCAGCTTTCAACCAGATTTCTGGGCCATGCATCTACCCGAAAAC
CCCTGGATCGTGCAGCCATTTGAGCGCTGGGAGCTGCTGCACCCCGGCGAACTCGAACCCATGAGCTAA

Upstream 100 bases:

>100_bases
TGCTGCGCTTTGGCTCCCGCGCTCCGGGCGCGCCCCAAGAGCTCACGCTCGCGGACATGCAGGATGTTCGTCGCAGACTG
GATCGGAAGGACTGGCCGCA

Downstream 100 bases:

>100_bases
TGGTCTATGCCATGGTTTTGCGCAGACCTTGGCCCGCTCCATGACCGGCACCCTGGCCCCCACCACCTTGAGCGACACCG
ATTGGAGCCAGGATCCGCGC

Product: phosphoribosyltransferase

Products: Diphosphate; Xanthosine 5'-phosphate [C]

Alternate protein names: Transferase; Xanthine-Guanine Phosphoribosyltransferase; Purine Phosphoribosyltransferase; Nucleotide Phosphoribosyltransferase; Phosphoribosyl Transferase Domain Protein; Xanthine Phosphoribosyltransferase; Phosphoribosyl Transferase Domain-Containing Protein; Phosphoribosyl Transferase Domain-Containing

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTALPQLKPPAISDNTAGELVVSWEQYHRLIEHLALQLHQAAADFDQIVALSRGGLRVGDLLSRLFDRPLVVMAASSYSG
DGDRIQGQLKLGHQLAHTCDQLGPRLLLVDDLVDSGTTLVEASAWLNTEVRPSQLLTGVLWLKGGSSFQPDFWAMHLPEN
PWIVQPFERWELLHPGELEPMS

Sequences:

>Translated_182_residues
MTALPQLKPPAISDNTAGELVVSWEQYHRLIEHLALQLHQAAADFDQIVALSRGGLRVGDLLSRLFDRPLVVMAASSYSG
DGDRIQGQLKLGHQLAHTCDQLGPRLLLVDDLVDSGTTLVEASAWLNTEVRPSQLLTGVLWLKGGSSFQPDFWAMHLPEN
PWIVQPFERWELLHPGELEPMS
>Mature_181_residues
TALPQLKPPAISDNTAGELVVSWEQYHRLIEHLALQLHQAAADFDQIVALSRGGLRVGDLLSRLFDRPLVVMAASSYSGD
GDRIQGQLKLGHQLAHTCDQLGPRLLLVDDLVDSGTTLVEASAWLNTEVRPSQLLTGVLWLKGGSSFQPDFWAMHLPENP
WIVQPFERWELLHPGELEPMS

Specific function: Acts On Guanine, Xanthine And To A Lesser Extent Hypoxanthine. [C]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.2.22 [C]

Molecular weight: Translated: 20190; Mature: 20059

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALPQLKPPAISDNTAGELVVSWEQYHRLIEHLALQLHQAAADFDQIVALSRGGLRVGD
CCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLSRLFDRPLVVMAASSYSGDGDRIQGQLKLGHQLAHTCDQLGPRLLLVDDLVDSGTTLV
HHHHHHCCCEEEEEECCCCCCCHHEEHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCEEE
EASAWLNTEVRPSQLLTGVLWLKGGSSFQPDFWAMHLPENPWIVQPFERWELLHPGELEP
EHHHHCCCCCCHHHHHHHHEEECCCCCCCCCEEEEECCCCCCEECCHHHCCCCCCCCCCC
MS
CC
>Mature Secondary Structure 
TALPQLKPPAISDNTAGELVVSWEQYHRLIEHLALQLHQAAADFDQIVALSRGGLRVGD
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLSRLFDRPLVVMAASSYSGDGDRIQGQLKLGHQLAHTCDQLGPRLLLVDDLVDSGTTLV
HHHHHHCCCEEEEEECCCCCCCHHEEHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCEEE
EASAWLNTEVRPSQLLTGVLWLKGGSSFQPDFWAMHLPENPWIVQPFERWELLHPGELEP
EHHHHCCCCCCHHHHHHHHEEECCCCCCCCCEEEEECCCCCCEECCHHHCCCCCCCCCCC
MS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.053 {5-phospho-alpha-D-ribose} 0.02 {xanthine}} [C]

Substrates: 5-Phospho-alpha-D-ribose 1-diphosphate; Xanthine [C]

Specific reaction: 5-Phospho-alpha-D-ribose 1-diphosphate + Xanthine --> Diphosphate + Xanthosine 5'-phosphate [C]

General reaction: Glycosyl and Pentosyl group transfer [C]

Inhibitor: 2-Thioxanthine; 6-Thioxanthine; 8-Mercaptoxanthine; ATP; CDP; CTP; GDP; GMP; GTP; TDP; TTP; UDP; UTP; Xanthine; XDP; XMP; XTP [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA