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The map label for this gene is mtnP [H]

Identifier: 148242455

GI number: 148242455

Start: 1202244

End: 1203185

Strand: Direct

Name: mtnP [H]

Synonym: SynRCC307_1356

Alternate gene names: 148242455

Gene position: 1202244-1203185 (Clockwise)

Preceding gene: 148242453

Following gene: 148242460

Centisome position: 54.04

GC content: 62.21

Gene sequence:

>942_bases
GTGGTCCATGAACCTTCGCACAAGACGATGGCGACTGCGCAACCACCTGTTTCCGACCTGAGCAACGCCACGATTGGCAT
CCTCGGCGGTAGCGGTCTCTATGCCATGGAGGAGCTGCGCGATGTGGAGGAGCTGGAGGTGCCAACGCCCTTTGGCCAGC
CATCGGATCGGCTGATCCGCGGCAATCTCGATGGCACCACGGTGATTTTTTTGGCCCGCCATGGGCGGCACCACAGCTAT
CTCCCTTCTGAGGTTCCCTACCGGGCCAACATCTGGGCGATGCGCAGCCTGGGCGTGCGCTGGATCCTCTCCTGCTCCGC
GGTTGGCTCACTGCAAGAGCAACACAGGCCCTTGGACCTGGTGATCCCGGATCAATTCATCGATCGAACCCAAGGGCGTG
CAGCCAGCTTTTTTGGCGAAGGAGCCGTGGCCCATGTGGCTTTTGCTGATCCCTTTTGCCAAACCCTTTCTGGACTCTTG
GCCGATGCTGCGCAATCGGTGCTGCCGGAAGGGCGCAGGCTGCACCGCGGCGGTACTTACCTCTGCATGCAAGGACCTGC
CTTCTCCACCAAGGCTGAATCTGAGCTGTACCGCAGCTGGGGCTGCGATGTGATCGGCATGACCAATCACACCGAAGCCC
GCTTGGCGCGTGAAGCCGAAATCGCCTACAGCACCTTGGCGATGGTGACCGACTACGACTGCTGGCATCCCGATCACGAT
GCCGTGACCGTTGAGATGGTGATCAACAACCTGCGCGCCAACGCCACCACAGCCCAGCAAGTGGTGCGCCATGCCGCCCA
GGCGATTCAGAAGCAAAAGCCCTCCAGCCCGGCCCACAGCGCGCTGCAAAACGGTTTGCTCACCGCGCCTGAGGCCGTGC
CGGCCGCCACCCGCCAAAAACTGGATCTGTTCACGCGCCCCTACTGGGGAGCGGCCAGCTGA

Upstream 100 bases:

>100_bases
AGTTGGCGACGGTGTTGGGAGCATCAGCATCAAATAGCTCCAGGGTGATTTGGCCGGCGTCGGTGTCCATCACGGCCTTG
GTCATGAGCTCGGGGGCAAA

Downstream 100 bases:

>100_bases
GCTCCAGCTTGTGCGAGGGCCTGACGCAAGGAACCATCAGAGCCCTGCAATTGCGCCAGCGCTGCAGGAGCGTCGCAGCC
CGTGGCCGCCATCAACAGGG

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MVHEPSHKTMATAQPPVSDLSNATIGILGGSGLYAMEELRDVEELEVPTPFGQPSDRLIRGNLDGTTVIFLARHGRHHSY
LPSEVPYRANIWAMRSLGVRWILSCSAVGSLQEQHRPLDLVIPDQFIDRTQGRAASFFGEGAVAHVAFADPFCQTLSGLL
ADAAQSVLPEGRRLHRGGTYLCMQGPAFSTKAESELYRSWGCDVIGMTNHTEARLAREAEIAYSTLAMVTDYDCWHPDHD
AVTVEMVINNLRANATTAQQVVRHAAQAIQKQKPSSPAHSALQNGLLTAPEAVPAATRQKLDLFTRPYWGAAS

Sequences:

>Translated_313_residues
MVHEPSHKTMATAQPPVSDLSNATIGILGGSGLYAMEELRDVEELEVPTPFGQPSDRLIRGNLDGTTVIFLARHGRHHSY
LPSEVPYRANIWAMRSLGVRWILSCSAVGSLQEQHRPLDLVIPDQFIDRTQGRAASFFGEGAVAHVAFADPFCQTLSGLL
ADAAQSVLPEGRRLHRGGTYLCMQGPAFSTKAESELYRSWGCDVIGMTNHTEARLAREAEIAYSTLAMVTDYDCWHPDHD
AVTVEMVINNLRANATTAQQVVRHAAQAIQKQKPSSPAHSALQNGLLTAPEAVPAATRQKLDLFTRPYWGAAS
>Mature_313_residues
MVHEPSHKTMATAQPPVSDLSNATIGILGGSGLYAMEELRDVEELEVPTPFGQPSDRLIRGNLDGTTVIFLARHGRHHSY
LPSEVPYRANIWAMRSLGVRWILSCSAVGSLQEQHRPLDLVIPDQFIDRTQGRAASFFGEGAVAHVAFADPFCQTLSGLL
ADAAQSVLPEGRRLHRGGTYLCMQGPAFSTKAESELYRSWGCDVIGMTNHTEARLAREAEIAYSTLAMVTDYDCWHPDHD
AVTVEMVINNLRANATTAQQVVRHAAQAIQKQKPSSPAHSALQNGLLTAPEAVPAATRQKLDLFTRPYWGAAS

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=265, Percent_Identity=42.6415094339623, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI71980569, Length=252, Percent_Identity=40.0793650793651, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323045, Length=320, Percent_Identity=37.5, Blast_Score=203, Evalue=4e-53,
Organism=Drosophila melanogaster, GI20130079, Length=265, Percent_Identity=38.4905660377359, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI221459247, Length=245, Percent_Identity=38.3673469387755, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 34165; Mature: 34165

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHEPSHKTMATAQPPVSDLSNATIGILGGSGLYAMEELRDVEELEVPTPFGQPSDRLIR
CCCCCCCCCEECCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
GNLDGTTVIFLARHGRHHSYLPSEVPYRANIWAMRSLGVRWILSCSAVGSLQEQHRPLDL
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEE
VIPDQFIDRTQGRAASFFGEGAVAHVAFADPFCQTLSGLLADAAQSVLPEGRRLHRGGTY
ECCHHHHHHCCCCHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHCCCCCEECCCCCE
LCMQGPAFSTKAESELYRSWGCDVIGMTNHTEARLAREAEIAYSTLAMVTDYDCWHPDHD
EEECCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AVTVEMVINNLRANATTAQQVVRHAAQAIQKQKPSSPAHSALQNGLLTAPEAVPAATRQK
CEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHH
LDLFTRPYWGAAS
HHHHCCCCCCCCC
>Mature Secondary Structure
MVHEPSHKTMATAQPPVSDLSNATIGILGGSGLYAMEELRDVEELEVPTPFGQPSDRLIR
CCCCCCCCCEECCCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
GNLDGTTVIFLARHGRHHSYLPSEVPYRANIWAMRSLGVRWILSCSAVGSLQEQHRPLDL
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCEEE
VIPDQFIDRTQGRAASFFGEGAVAHVAFADPFCQTLSGLLADAAQSVLPEGRRLHRGGTY
ECCHHHHHHCCCCHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHCCCCCEECCCCCE
LCMQGPAFSTKAESELYRSWGCDVIGMTNHTEARLAREAEIAYSTLAMVTDYDCWHPDHD
EEECCCCCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AVTVEMVINNLRANATTAQQVVRHAAQAIQKQKPSSPAHSALQNGLLTAPEAVPAATRQK
CEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHH
LDLFTRPYWGAAS
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA